# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 16 #b referenced loci : 15 #c annotated loci : 12 #d hyper-geometric : n 12 hgN 14129 #e k hgK Exp k p-value term description 2 15 0 6.90091e-05 GO:0008286 insulin receptor signaling pathway 8 2707 2.2 0.000424495 GO:0005737 cytoplasm 2 63 0 0.00125482 GO:0030036 actin cytoskeleton organization and biogenesis 2 67 0 0.00141791 GO:0030029 actin filament-based process 1 2 0 0.00169797 GO:0004740 [pyruvate dehydrogenase (lipoamide)] kinase activity 2 75 0 0.0017729 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1 3 0 0.00254597 GO:0043149 stress fiber formation 1 3 0 0.00254597 GO:0048041 focal adhesion formation 2 102 0 0.00324923 GO:0019866 inner membrane 1 4 0 0.0033933 GO:0001515 opioid peptide activity 1 5 0 0.00423998 GO:0008290 F-actin capping protein complex 2 118 0.1 0.00432164 GO:0007167 enzyme linked receptor protein signaling pathway 1 6 0 0.00508599 GO:0001725 stress fiber 2 130 0.1 0.00521983 GO:0015629 actin cytoskeleton 1 7 0 0.00593135 GO:0051017 actin filament bundle formation 1 9 0 0.00762009 GO:0017124 SH3 domain binding 2 160 0.1 0.00780722 GO:0003779 actin binding 3 514 0.4 0.00823795 GO:0005856 cytoskeleton 1 10 0 0.00846347 GO:0005913 cell-cell adherens junction 1 11 0 0.00930619 GO:0005158 insulin receptor binding 1 11 0 0.00930619 GO:0008645 hexose transport 1 11 0 0.00930619 GO:0015749 monosaccharide transport 1 11 0 0.00930619 GO:0015758 glucose transport 1 13 0 0.0109897 GO:0045121 lipid raft 1 14 0 0.0118304 GO:0005924 cell-substrate adherens junction 2 204 0.1 0.0124479 GO:0007010 cytoskeleton organization and biogenesis 1 16 0 0.01351 GO:0030055 cell-matrix junction 3 632 0.5 0.0144791 GO:0005739 mitochondrion 3 634 0.5 0.0146031 GO:0005886 plasma membrane 2 222 0.1 0.0146229 GO:0008092 cytoskeletal protein binding 1 18 0 0.0151869 GO:0007015 actin filament organization 2 244 0.2 0.0174897 GO:0006996 organelle organization and biogenesis 1 22 0 0.0185329 GO:0019901 protein kinase binding 10 7041 5.9 0.0187181 GO:0005488 binding 1 23 0 0.0193678 GO:0005905 coated pit 1 24 0 0.020202 GO:0019900 kinase binding 1 25 0 0.0210356 GO:0007249 I-kappaB kinase/NF-kappaB cascade 5 2064 1.7 0.0214436 GO:0005515 protein binding 1 27 0 0.0227008 GO:0008643 carbohydrate transport 2 286 0.2 0.0235724 GO:0007028 cytoplasm organization and biogenesis 1 32 0 0.0268525 GO:0005912 adherens junction 1 32 0 0.0268525 GO:0019904 protein domain specific binding 1 34 0 0.0285086 GO:0008203 cholesterol metabolism 1 37 0 0.0309879 GO:0005319 lipid transporter activity 1 38 0 0.0318131 GO:0016125 sterol metabolism 11 9173 7.7 0.0419036 GO:0005623 cell 1 53 0 0.0441134 GO:0006869 lipid transport 1 53 0 0.0441134 GO:0019899 enzyme binding 1 55 0 0.0457426 GO:0007160 cell-matrix adhesion 2 433 0.3 0.0504805 GO:0005102 receptor binding 8 5553 4.7 0.051587 GO:0005622 intracellular 1 65 0 0.0538504 GO:0015293 symporter activity 1 79 0 0.0650952 GO:0007517 muscle development 1 81 0 0.0666916 GO:0005743 mitochondrial inner membrane 1 82 0 0.0674888 GO:0008202 steroid metabolism 1 95 0 0.0777964 GO:0004222 metalloendopeptidase activity 1 96 0 0.0785849 GO:0005911 intercellular junction 2 582 0.4 0.085086 GO:0016043 cell organization and biogenesis 1 109 0 0.0887799 GO:0005740 mitochondrial membrane 1 111 0 0.0903392 GO:0016327 apicolateral plasma membrane 1 117 0 0.0950023 GO:0006897 endocytosis 1 119 0.1 0.0965518 GO:0007243 protein kinase cascade 1 119 0.1 0.0965518 GO:0030054 cell junction 1 158 0.1 0.126285 GO:0008237 metallopeptidase activity 1 159 0.1 0.127035 GO:0006066 alcohol metabolism 1 161 0.1 0.128534 GO:0015291 porter activity 1 162 0.1 0.129283 GO:0015290 electrochemical potential-driven transporter activity 1 165 0.1 0.131526 GO:0005624 membrane fraction 1 180 0.1 0.142659 GO:0000267 cell fraction 6 4555 3.8 0.15643 GO:0016020 membrane 1 200 0.1 0.1573 GO:0005829 cytosol 3 1656 1.4 0.158323 GO:0006810 transport 1 212 0.1 0.165974 GO:0016192 vesicle-mediated transport 7 5831 4.9 0.181478 GO:0009987 cellular process 4 2728 2.3 0.187284 GO:0007165 signal transduction 4 2750 2.3 0.191291 GO:0008151 cell growth and/or maintenance 3 5837 4.9 0.198374 u GO:0008152 metabolism 2 4537 3.8 0.205399 u GO:0003824 catalytic activity 2 1067 0.9 0.228184 GO:0005524 ATP binding 2 1078 0.9 0.231727 GO:0030554 adenyl nucleotide binding 1 311 0.2 0.234475 GO:0005386 carrier activity 1 337 0.2 0.251589 GO:0006118 electron transport 2 1147 0.9 0.254085 GO:0005215 transporter activity 1 350 0.2 0.260014 GO:0006629 lipid metabolism 4 3131 2.6 0.265589 GO:0050875 cellular physiological process 4 3170 2.6 0.273643 GO:0007154 cell communication 1 375 0.3 0.275971 GO:0003723 RNA binding 1 390 0.3 0.285394 GO:0007155 cell adhesion 1 456 0.3 0.325533 GO:0004175 endopeptidase activity 2 1366 1.1 0.325705 GO:0017076 purine nucleotide binding 2 1374 1.1 0.32832 GO:0000166 nucleotide binding 6 8414 7.1 0.346689 u GO:0007582 physiological process 1 500 0.4 0.351132 GO:0005509 calcium ion binding 1 2384 2 0.373937 u GO:0019538 protein metabolism 1 2359 2 0.380181 u GO:0004872 receptor activity 1 586 0.4 0.398614 GO:0016773 phosphotransferase activity, alcohol group as acceptor 1 590 0.5 0.400742 GO:0006508 proteolysis and peptidolysis 1 610 0.5 0.411284 GO:0030163 protein catabolism 1 613 0.5 0.41285 GO:0009057 macromolecule catabolism 1 622 0.5 0.417526 GO:0008233 peptidase activity 1 660 0.5 0.436897 GO:0007242 intracellular signaling cascade 1 698 0.5 0.455676 GO:0009887 organogenesis 3 2958 2.5 0.474622 GO:0004871 signal transducer activity 1 749 0.6 0.479977 GO:0016301 kinase activity 2 1874 1.5 0.486053 GO:0046872 metal ion binding 1 771 0.6 0.490149 GO:0016772 transferase activity, transferring phosphorus-containing groups 2 1922 1.6 0.500293 GO:0007166 cell surface receptor linked signal transduction 1 797 0.6 0.501936 GO:0009056 catabolism 1 822 0.6 0.513033 GO:0009653 morphogenesis 1 1795 1.5 0.537804 u GO:0016787 hydrolase activity 2 2672 2.2 0.59712 u GO:0003676 nucleic acid binding 2 2670 2.2 0.597626 u GO:0005634 nucleus 1 1095 0.9 0.620314 GO:0008270 zinc ion binding 3 3552 3 0.644471 u GO:0016021 integral to membrane 1 1415 1.2 0.658302 u GO:0007275 development 1 1372 1.1 0.672334 u GO:0016740 transferase activity 1 1221 1 0.721764 u GO:0046914 transition metal ion binding