# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 23 #b referenced loci : 22 #c annotated loci : 19 #d hyper-geometric : n 19 hgN 14129 #e k hgK Exp k p-value term description 2 15 0 0.00017803 GO:0008286 insulin receptor signaling pathway 10 2707 3.6 0.00110636 GO:0005737 cytoplasm 1 2 0 0.00268779 GO:0004740 [pyruvate dehydrogenase (lipoamide)] kinase activity 2 63 0 0.00318644 GO:0030036 actin cytoskeleton organization and biogenesis 2 67 0 0.00359585 GO:0030029 actin filament-based process 1 3 0 0.00402912 GO:0008475 procollagen-lysine 5-dioxygenase activity 1 3 0 0.00402912 GO:0043149 stress fiber formation 1 3 0 0.00402912 GO:0048041 focal adhesion formation 2 75 0.1 0.00448432 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1 4 0 0.00536874 GO:0001515 opioid peptide activity 1 4 0 0.00536874 GO:0004449 isocitrate dehydrogenase (NAD+) activity 1 5 0 0.00670665 GO:0008290 F-actin capping protein complex 1 6 0 0.00804285 GO:0001725 stress fiber 1 6 0 0.00804285 GO:0004448 isocitrate dehydrogenase activity 2 102 0.1 0.00814618 GO:0019866 inner membrane 4 632 0.8 0.00898484 GO:0005739 mitochondrion 1 7 0 0.00937736 GO:0051017 actin filament bundle formation 2 114 0.1 0.0100892 GO:0015980 energy derivation by oxidation of organic compounds 2 118 0.1 0.0107784 GO:0007167 enzyme linked receptor protein signaling pathway 2 120 0.1 0.0111306 GO:0006091 energy pathways 1 9 0 0.0120413 GO:0017124 SH3 domain binding 2 130 0.1 0.0129676 GO:0015629 actin cytoskeleton 1 10 0 0.0133707 GO:0005913 cell-cell adherens junction 1 11 0 0.0146984 GO:0005158 insulin receptor binding 1 11 0 0.0146984 GO:0008645 hexose transport 1 11 0 0.0146984 GO:0015749 monosaccharide transport 1 11 0 0.0146984 GO:0015758 glucose transport 1 13 0 0.0173487 GO:0045121 lipid raft 1 14 0 0.0186714 GO:0005924 cell-substrate adherens junction 2 160 0.2 0.0192071 GO:0003779 actin binding 1 16 0 0.0213116 GO:0030055 cell-matrix junction 1 18 0 0.0239451 GO:0007015 actin filament organization 1 19 0 0.0252593 GO:0005977 glycogen metabolism 1 19 0 0.0252593 GO:0006073 glucan metabolism 1 20 0 0.0265719 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 1 21 0 0.0278827 GO:0006099 tricarboxylic acid cycle 1 22 0 0.0291919 GO:0019901 protein kinase binding 3 514 0.6 0.030061 GO:0005856 cytoskeleton 2 204 0.2 0.0301908 GO:0007010 cytoskeleton organization and biogenesis 12 5553 7.4 0.0304526 GO:0005622 intracellular 1 23 0 0.0304995 GO:0005905 coated pit 14 7041 9.4 0.0306786 GO:0005488 binding 1 24 0 0.0318053 GO:0006112 energy reserve metabolism 1 24 0 0.0318053 GO:0019900 kinase binding 1 25 0 0.0331095 GO:0007249 I-kappaB kinase/NF-kappaB cascade 2 222 0.2 0.0352604 GO:0008092 cytoskeletal protein binding 1 27 0 0.0357129 GO:0008643 carbohydrate transport 1 28 0 0.0370121 GO:0005976 polysaccharide metabolism 1 31 0 0.0408998 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2 244 0.3 0.0418756 GO:0006996 organelle organization and biogenesis 1 32 0 0.0421924 GO:0005912 adherens junction 1 32 0 0.0421924 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1 32 0 0.0421924 GO:0019904 protein domain specific binding 1 34 0 0.0447726 GO:0008203 cholesterol metabolism 6 2064 2.7 0.0479298 GO:0005515 protein binding 1 37 0 0.0486306 GO:0005319 lipid transporter activity 1 38 0 0.0499133 GO:0016125 sterol metabolism 3 634 0.8 0.0510189 GO:0005886 plasma membrane 2 286 0.3 0.0556848 GO:0007028 cytoplasm organization and biogenesis 2 293 0.3 0.0581264 GO:0005975 carbohydrate metabolism 1 53 0 0.0689585 GO:0006869 lipid transport 1 53 0 0.0689585 GO:0019899 enzyme binding 1 55 0 0.0714704 GO:0007160 cell-matrix adhesion 1 65 0 0.0839337 GO:0015293 symporter activity 1 74 0 0.095015 GO:0005516 calmodulin binding 1 79 0.1 0.101116 GO:0007517 muscle development 1 81 0.1 0.103546 GO:0005743 mitochondrial inner membrane 1 82 0.1 0.104758 GO:0008202 steroid metabolism 1 88 0.1 0.112001 GO:0006092 main pathways of carbohydrate metabolism 2 433 0.5 0.113827 GO:0005102 receptor binding 1 91 0.1 0.115601 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1 95 0.1 0.12038 GO:0004222 metalloendopeptidase activity 1 96 0.1 0.12157 GO:0005911 intercellular junction 1 97 0.1 0.12276 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1 103 0.1 0.129864 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1 104 0.1 0.131043 GO:0008415 acyltransferase activity 1 107 0.1 0.13457 GO:0016747 transferase activity, transferring groups other than amino-acyl groups 1 109 0.1 0.136914 GO:0005740 mitochondrial membrane 1 111 0.1 0.139251 GO:0016327 apicolateral plasma membrane 2 500 0.6 0.144077 GO:0005509 calcium ion binding 1 117 0.1 0.146229 GO:0006897 endocytosis 1 118 0.1 0.147387 GO:0016746 transferase activity, transferring acyl groups 15 9173 12.3 0.148222 GO:0005623 cell 1 119 0.1 0.148543 GO:0007243 protein kinase cascade 1 119 0.1 0.148543 GO:0030054 cell junction 1 2359 3.1 0.149306 u GO:0004872 receptor activity 1 129 0.1 0.160024 GO:0006260 DNA replication 2 582 0.7 0.183199 GO:0016043 cell organization and biogenesis 1 152 0.2 0.185875 GO:0000067 DNA replication and chromosome cycle 2 599 0.8 0.191527 GO:0016491 oxidoreductase activity 1 158 0.2 0.192494 GO:0008237 metallopeptidase activity 1 159 0.2 0.193592 GO:0006066 alcohol metabolism 1 161 0.2 0.195784 GO:0015291 porter activity 1 162 0.2 0.196878 GO:0015290 electrochemical potential-driven transporter activity 1 165 0.2 0.200152 GO:0005624 membrane fraction 1 180 0.2 0.21633 GO:0000267 cell fraction 1 200 0.2 0.237419 GO:0005829 cytosol 1 212 0.2 0.249813 GO:0016192 vesicle-mediated transport 3 3552 4.7 0.25842 u GO:0016021 integral to membrane 1 1795 2.4 0.284667 u GO:0016787 hydrolase activity 5 2750 3.6 0.304851 GO:0008151 cell growth and/or maintenance 1 311 0.4 0.345027 GO:0005386 carrier activity 2 2384 3.2 0.355235 u GO:0019538 protein metabolism 2 2374 3.1 0.358289 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 327 0.4 0.359297 GO:0005783 endoplasmic reticulum 1 337 0.4 0.368065 GO:0006118 electron transport 9 5837 7.8 0.376543 GO:0008152 metabolism 1 350 0.4 0.379294 GO:0006629 lipid metabolism 3 1656 2.2 0.388101 GO:0006810 transport 5 4537 6.1 0.394916 u GO:0003824 catalytic activity 1 375 0.5 0.40036 GO:0003723 RNA binding 1 390 0.5 0.412672 GO:0007155 cell adhesion 3 2958 3.9 0.414906 u GO:0004871 signal transducer activity 7 4555 6.1 0.416131 GO:0016020 membrane 5 3131 4.2 0.416683 GO:0050875 cellular physiological process 1 1415 1.9 0.419256 u GO:0007275 development 2 1067 1.4 0.426026 GO:0005524 ATP binding 2 1078 1.4 0.431311 GO:0030554 adenyl nucleotide binding 2 1147 1.5 0.463942 GO:0005215 transporter activity 1 456 0.6 0.464055 GO:0004175 endopeptidase activity 2 2048 2.7 0.466069 u GO:0050789 regulation of biological process 3 1874 2.5 0.470793 GO:0046872 metal ion binding 12 8414 11.3 0.471646 GO:0007582 physiological process 1 491 0.6 0.489546 GO:0007049 cell cycle 4 2670 3.5 0.495946 GO:0005634 nucleus 4 2672 3.5 0.496586 GO:0003676 nucleic acid binding 1 505 0.6 0.499417 GO:0006259 DNA metabolism 1 1221 1.6 0.502143 u GO:0046914 transition metal ion binding 2 1922 2.5 0.511474 u GO:0007166 cell surface receptor linked signal transduction 4 2728 3.6 0.514408 GO:0007165 signal transduction 1 586 0.7 0.553072 GO:0016773 phosphotransferase activity, alcohol group as acceptor 1 590 0.7 0.555575 GO:0006508 proteolysis and peptidolysis 8 5831 7.8 0.557584 GO:0009987 cellular process 1 596 0.8 0.559304 GO:0003700 transcription factor activity 1 1095 1.4 0.560566 u GO:0008270 zinc ion binding 2 1366 1.8 0.560679 GO:0017076 purine nucleotide binding 2 1372 1.8 0.563168 GO:0016740 transferase activity 2 1374 1.8 0.563996 GO:0000166 nucleotide binding 1 610 0.8 0.567892 GO:0030163 protein catabolism 1 613 0.8 0.569711 GO:0009057 macromolecule catabolism 4 3170 4.2 0.571707 u GO:0007154 cell communication 2 1393 1.8 0.57181 GO:0006355 regulation of transcription, DNA-dependent 1 619 0.8 0.573329 GO:0008283 cell proliferation 1 622 0.8 0.575126 GO:0008233 peptidase activity 2 1417 1.9 0.58155 GO:0006351 transcription, DNA-dependent 2 1452 1.9 0.595491 GO:0045449 regulation of transcription 1 660 0.8 0.597286 GO:0007242 intracellular signaling cascade 2 1458 1.9 0.59785 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 698 0.9 0.618347 GO:0009887 organogenesis 2 1606 2.1 0.63117 u GO:0050791 regulation of physiological process 2 1604 2.1 0.631941 u GO:0003677 DNA binding 2 1564 2.1 0.647383 u GO:0019222 regulation of metabolism 2 1516 2 0.665905 u GO:0006350 transcription 1 822 1.1 0.695972 u GO:0009653 morphogenesis 1 797 1 0.708696 u GO:0009056 catabolism 1 776 1 0.719389 u GO:0030528 transcription regulator activity 1 771 1 0.721935 u GO:0016772 transferase activity, transferring phosphorus-containing groups 1 749 1 0.733132 u GO:0016301 kinase activity