# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 26 #b referenced loci : 26 #c annotated loci : 19 #d hyper-geometric : n 19 hgN 14129 #e k hgK Exp k p-value term description 13 4537 6.1 0.0012609 GO:0003824 catalytic activity 1 1 0 0.00134475 GO:0047372 acylglycerol lipase activity 2 51 0 0.00210032 GO:0016042 lipid catabolism 1 3 0 0.00402912 GO:0004652 polynucleotide adenylyltransferase activity 1 3 0 0.00402912 GO:0043149 stress fiber formation 1 3 0 0.00402912 GO:0048041 focal adhesion formation 1 4 0 0.00536874 GO:0003997 acyl-CoA oxidase activity 1 4 0 0.00536874 GO:0004449 isocitrate dehydrogenase (NAD+) activity 1 4 0 0.00536874 GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors 2 88 0.1 0.00612198 GO:0006092 main pathways of carbohydrate metabolism 1 5 0 0.00670665 GO:0004287 prolyl oligopeptidase activity 1 5 0 0.00670665 GO:0004396 hexokinase activity 1 6 0 0.00804285 GO:0001725 stress fiber 1 6 0 0.00804285 GO:0004448 isocitrate dehydrogenase activity 1 7 0 0.00937736 GO:0051017 actin filament bundle formation 2 114 0.1 0.0100892 GO:0015980 energy derivation by oxidation of organic compounds 1 8 0 0.0107102 GO:0006635 fatty acid beta-oxidation 1 8 0 0.0107102 GO:0019905 syntaxin binding 3 350 0.4 0.0108776 GO:0006629 lipid metabolism 2 120 0.1 0.0111306 GO:0006091 energy pathways 1 9 0 0.0120413 GO:0000086 G2/M transition of mitotic cell cycle 1 9 0 0.0120413 GO:0009618 response to pathogenic bacteria 1 9 0 0.0120413 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1 10 0 0.0133707 GO:0005913 cell-cell adherens junction 1 10 0 0.0133707 GO:0016358 dendrite morphogenesis 1 11 0 0.0146984 GO:0000149 SNARE binding 1 11 0 0.0146984 GO:0005158 insulin receptor binding 1 11 0 0.0146984 GO:0007586 digestion 1 11 0 0.0146984 GO:0008645 hexose transport 1 11 0 0.0146984 GO:0015749 monosaccharide transport 1 11 0 0.0146984 GO:0015758 glucose transport 2 141 0.1 0.0151309 GO:0000287 magnesium ion binding 13 5837 7.8 0.0156367 GO:0008152 metabolism 1 13 0 0.0173487 GO:0019395 fatty acid oxidation 1 13 0 0.0173487 GO:0045121 lipid raft 1 14 0 0.0186714 GO:0005924 cell-substrate adherens junction 4 797 1 0.0197509 GO:0009056 catabolism 1 15 0 0.0199923 GO:0004722 protein serine/threonine phosphatase activity 1 15 0 0.0199923 GO:0004759 serine esterase activity 1 15 0 0.0199923 GO:0008286 insulin receptor signaling pathway 16 8414 11.3 0.020881 GO:0007582 physiological process 1 16 0 0.0213116 GO:0006289 nucleotide-excision repair 1 16 0 0.0213116 GO:0030055 cell-matrix junction 1 18 0 0.0239451 GO:0007015 actin filament organization 6 1795 2.4 0.0260749 GO:0016787 hydrolase activity 1 20 0 0.0265719 GO:0004091 carboxylesterase activity 1 20 0 0.0265719 GO:0019200 carbohydrate kinase activity 1 21 0 0.0278827 GO:0006099 tricarboxylic acid cycle 1 21 0 0.0278827 GO:0008287 protein serine/threonine phosphatase complex 1 22 0 0.0291919 GO:0019901 protein kinase binding 3 514 0.6 0.030061 GO:0005856 cytoskeleton 1 24 0 0.0318053 GO:0019900 kinase binding 1 25 0 0.0331095 GO:0009617 response to bacteria 1 27 0 0.0357129 GO:0008643 carbohydrate transport 1 28 0 0.0370121 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1 32 0 0.0421924 GO:0005912 adherens junction 3 594 0.7 0.0433897 GO:0016788 hydrolase activity, acting on ester bonds 3 599 0.8 0.0443086 GO:0016491 oxidoreductase activity 2 264 0.3 0.0482663 GO:0016567 protein ubiquitination 2 268 0.3 0.0495856 GO:0000151 ubiquitin ligase complex 4 1067 1.4 0.0503412 GO:0005524 ATP binding 3 632 0.8 0.0506224 GO:0005739 mitochondrion 1 3170 4.2 0.0519104 u GO:0007154 cell communication 4 1078 1.4 0.0519556 GO:0030554 adenyl nucleotide binding 1 42 0 0.0550278 GO:0030145 manganese ion binding 7 2707 3.6 0.0552469 GO:0005737 cytoplasm 4 5831 7.8 0.0558934 u GO:0009987 cellular process 2 293 0.3 0.0581264 GO:0005975 carbohydrate metabolism 1 48 0 0.0626507 GO:0006096 glycolysis 2 307 0.4 0.0631218 GO:0004842 ubiquitin-protein ligase activity 4 1161 1.5 0.0650812 GO:0006464 protein modification 1 51 0 0.0664402 GO:0005941 unlocalized 1 53 0 0.0689585 GO:0019899 enzyme binding 2 326 0.4 0.0701307 GO:0016881 acid-D-amino acid ligase activity 1 54 0 0.0702153 GO:0005777 peroxisome 1 54 0 0.0702153 GO:0042579 microbody 1 55 0 0.0714704 GO:0007160 cell-matrix adhesion 1 56 0 0.0727239 GO:0006007 glucose catabolism 1 57 0 0.0739758 GO:0019320 hexose catabolism 1 57 0 0.0739758 GO:0046164 alcohol catabolism 1 57 0 0.0739758 GO:0046365 monosaccharide catabolism 2 337 0.4 0.0743035 GO:0006118 electron transport 11 5553 7.4 0.0785276 GO:0005622 intracellular 1 63 0 0.0814538 GO:0030036 actin cytoskeleton organization and biogenesis 3 771 1 0.0817905 GO:0016772 transferase activity, transferring phosphorus-containing groups 2 358 0.4 0.0824911 GO:0015031 protein transport 1 64 0 0.0826945 GO:0016052 carbohydrate catabolism 2 360 0.4 0.0832854 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1 67 0 0.0864073 GO:0030029 actin filament-based process 2 368 0.4 0.0864872 GO:0006512 ubiquitin cycle 1 73 0 0.0937901 GO:0005875 microtubule associated complex 3 4555 6.1 0.0939593 u GO:0016020 membrane 1 2728 3.6 0.0939947 u GO:0007165 signal transduction 1 74 0 0.095015 GO:0005516 calmodulin binding 1 75 0.1 0.0962384 GO:0006006 glucose metabolism 1 75 0.1 0.0962384 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 5 1874 2.5 0.0966388 GO:0046872 metal ion binding 4 1366 1.8 0.104503 GO:0017076 purine nucleotide binding 1 83 0.1 0.105969 GO:0016789 carboxylic ester hydrolase activity 4 1374 1.8 0.106236 GO:0000166 nucleotide binding 1 86 0.1 0.109593 GO:0006725 aromatic compound metabolism 1 90 0.1 0.114402 GO:0008047 enzyme activator activity 1 91 0.1 0.115601 GO:0019318 hexose metabolism 1 92 0.1 0.116798 GO:0006631 fatty acid metabolism 1 93 0.1 0.117993 GO:0005996 monosaccharide metabolism 1 95 0.1 0.12038 GO:0007283 spermatogenesis 1 95 0.1 0.12038 GO:0048232 male gamete generation 1 96 0.1 0.12157 GO:0005911 intercellular junction 1 97 0.1 0.12276 GO:0006397 mRNA processing 1 97 0.1 0.12276 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2 460 0.6 0.125796 GO:0016874 ligase activity 1 103 0.1 0.129864 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5 2064 2.7 0.132691 GO:0005515 protein binding 1 106 0.1 0.133396 GO:0016071 mRNA metabolism 1 110 0.1 0.138083 GO:0006470 protein amino acid dephosphorylation 1 111 0.1 0.139251 GO:0016327 apicolateral plasma membrane 1 112 0.1 0.140418 GO:0016311 dephosphorylation 1 118 0.1 0.147387 GO:0000278 mitotic cell cycle 1 118 0.1 0.147387 GO:0007167 enzyme linked receptor protein signaling pathway 1 119 0.1 0.148543 GO:0030054 cell junction 1 2359 3.1 0.149306 u GO:0004872 receptor activity 2 517 0.6 0.152023 GO:0006950 response to stress 1 125 0.1 0.155449 GO:0006281 DNA repair 1 128 0.1 0.158882 GO:0004721 phosphoprotein phosphatase activity 1 130 0.1 0.161163 GO:0015629 actin cytoskeleton 1 131 0.1 0.162302 GO:0003774 motor activity 1 136 0.1 0.167973 GO:0016779 nucleotidyltransferase activity 1 138 0.1 0.170231 GO:0015630 microtubule cytoskeleton 12 7041 9.4 0.175667 GO:0005488 binding 1 149 0.2 0.182546 GO:0006974 response to DNA damage stimulus 2 586 0.7 0.185153 GO:0016773 phosphotransferase activity, alcohol group as acceptor 1 157 0.2 0.191394 GO:0004252 serine-type endopeptidase activity 1 157 0.2 0.191394 GO:0009719 response to endogenous stimulus 1 159 0.2 0.193592 GO:0006066 alcohol metabolism 1 169 0.2 0.204496 GO:0008236 serine-type peptidase activity 5 2384 3.2 0.206043 GO:0019538 protein metabolism 2 2958 3.9 0.207499 u GO:0004871 signal transducer activity 1 178 0.2 0.214191 GO:0007276 gametogenesis 1 185 0.2 0.221653 GO:0006396 RNA processing 3 1221 1.6 0.222917 GO:0046914 transition metal ion binding 1 187 0.2 0.223773 GO:0016791 phosphoric monoester hydrolase activity 2 669 0.8 0.226367 GO:0006793 phosphorus metabolism 2 669 0.8 0.226367 GO:0006796 phosphate metabolism 1 200 0.2 0.237419 GO:0005829 cytosol 1 203 0.2 0.240535 GO:0000003 reproduction 1 203 0.2 0.240535 GO:0019953 sexual reproduction 1 204 0.2 0.241571 GO:0007010 cytoskeleton organization and biogenesis 1 1922 2.5 0.247884 u GO:0007166 cell surface receptor linked signal transduction 1 211 0.2 0.248787 GO:0004518 nuclease activity 2 749 1 0.266868 GO:0016301 kinase activity 1 235 0.3 0.273037 GO:0009613 response to pest/pathogen/parasite 2 2672 3.5 0.27429 u GO:0003676 nucleic acid binding 1 238 0.3 0.276015 GO:0016070 RNA metabolism 3 1372 1.8 0.278969 GO:0016740 transferase activity 1 243 0.3 0.280954 GO:0042578 phosphoric ester hydrolase activity 1 244 0.3 0.281937 GO:0006996 organelle organization and biogenesis 1 259 0.3 0.296543 GO:0007399 neurogenesis 1 262 0.3 0.29943 GO:0019752 carboxylic acid metabolism 1 265 0.3 0.302306 GO:0006082 organic acid metabolism 1 280 0.3 0.316519 GO:0005794 Golgi apparatus 1 286 0.3 0.322127 GO:0007028 cytoplasm organization and biogenesis 11 9173 12.3 0.336967 u GO:0005623 cell 1 1604 2.1 0.34764 u GO:0003677 DNA binding 2 2374 3.1 0.358289 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 327 0.4 0.359297 GO:0005783 endoplasmic reticulum 1 345 0.4 0.374998 GO:0004674 protein serine/threonine kinase activity 1 1516 2 0.379832 u GO:0006350 transcription 3 1656 2.2 0.388101 GO:0006810 transport 1 375 0.5 0.40036 GO:0003723 RNA binding 1 384 0.5 0.407776 GO:0030234 enzyme regulator activity 1 390 0.5 0.412672 GO:0007155 cell adhesion 2 1058 1.4 0.421687 GO:0050896 response to stimulus 2 1095 1.4 0.439434 GO:0008270 zinc ion binding 1 433 0.5 0.446653 GO:0005102 receptor binding 1 456 0.6 0.464055 GO:0004175 endopeptidase activity 1 491 0.6 0.489546 GO:0007049 cell cycle 1 496 0.6 0.493092 GO:0004672 protein kinase activity 1 505 0.6 0.499417 GO:0006259 DNA metabolism 1 509 0.6 0.502204 GO:0006468 protein amino acid phosphorylation 3 2670 3.5 0.504054 u GO:0005634 nucleus 4 2750 3.6 0.521353 GO:0008151 cell growth and/or maintenance 1 559 0.7 0.535823 GO:0016310 phosphorylation 1 578 0.7 0.548025 GO:0009607 response to biotic stimulus 1 582 0.7 0.550555 GO:0016043 cell organization and biogenesis 1 590 0.7 0.555575 GO:0006508 proteolysis and peptidolysis 1 610 0.8 0.567892 GO:0030163 protein catabolism 1 613 0.8 0.569711 GO:0009057 macromolecule catabolism 1 619 0.8 0.573329 GO:0008283 cell proliferation 1 622 0.8 0.575126 GO:0008233 peptidase activity 1 625 0.8 0.576917 GO:0005198 structural molecule activity 2 1415 1.9 0.580744 GO:0007275 development 1 634 0.8 0.582246 GO:0005886 plasma membrane 4 3131 4.2 0.583317 u GO:0050875 cellular physiological process 1 698 0.9 0.618347 GO:0009887 organogenesis 1 723 0.9 0.63163 GO:0005576 extracellular 1 884 1.1 0.664526 u GO:0050874 organismal physiological process 1 879 1.1 0.667053 u GO:0009605 response to external stimulus 1 822 1.1 0.695972 u GO:0009653 morphogenesis