# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 35 #b referenced loci : 35 #c annotated loci : 26 #d hyper-geometric : n 26 hgN 14129 #e k hgK Exp k p-value term description 19 5837 10.7 0.00103475 GO:0008152 metabolism 1 1 0 0.00184019 GO:0047372 acylglycerol lipase activity 16 4537 8.3 0.00190204 GO:0003824 catalytic activity 1 2 0 0.00367712 GO:0004020 adenylyl-sulfate kinase activity 1 2 0 0.00367712 GO:0004779 sulfate adenylyltransferase activity 1 2 0 0.00367712 GO:0004781 sulfate adenylyltransferase (ATP) activity 2 51 0 0.00392797 GO:0016042 lipid catabolism 1 3 0 0.0055108 GO:0004652 polynucleotide adenylyltransferase activity 1 3 0 0.0055108 GO:0043149 stress fiber formation 1 3 0 0.0055108 GO:0048041 focal adhesion formation 22 8414 15.4 0.00580977 GO:0007582 physiological process 1 4 0 0.00734123 GO:0000103 sulfate assimilation 1 4 0 0.00734123 GO:0003997 acyl-CoA oxidase activity 1 4 0 0.00734123 GO:0004449 isocitrate dehydrogenase (NAD+) activity 1 4 0 0.00734123 GO:0006791 sulfur utilization 1 4 0 0.00734123 GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors 1 5 0 0.00916843 GO:0004287 prolyl oligopeptidase activity 1 5 0 0.00916843 GO:0004396 hexokinase activity 1 6 0 0.0109924 GO:0001725 stress fiber 1 6 0 0.0109924 GO:0004448 isocitrate dehydrogenase activity 2 88 0.1 0.0113118 GO:0006092 main pathways of carbohydrate metabolism 6 1067 1.9 0.0113538 GO:0005524 ATP binding 6 1078 1.9 0.0119105 GO:0030554 adenyl nucleotide binding 5 771 1.4 0.0120678 GO:0016772 transferase activity, transferring phosphorus-containing groups 1 7 0 0.0128131 GO:0051017 actin filament bundle formation 5 797 1.4 0.0137918 GO:0009056 catabolism 19 7041 12.9 0.013801 GO:0005488 binding 1 8 0 0.0146306 GO:0006635 fatty acid beta-oxidation 1 8 0 0.0146306 GO:0019905 syntaxin binding 5 5831 10.7 0.0155741 u GO:0009987 cellular process 1 9 0 0.0164449 GO:0000086 G2/M transition of mitotic cell cycle 1 9 0 0.0164449 GO:0009618 response to pathogenic bacteria 1 9 0 0.0164449 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1 10 0 0.018256 GO:0005913 cell-cell adherens junction 1 10 0 0.018256 GO:0016358 dendrite morphogenesis 2 114 0.2 0.0184855 GO:0015980 energy derivation by oxidation of organic compounds 1 11 0 0.0200639 GO:0000149 SNARE binding 1 11 0 0.0200639 GO:0005158 insulin receptor binding 1 11 0 0.0200639 GO:0007586 digestion 1 11 0 0.0200639 GO:0008645 hexose transport 1 11 0 0.0200639 GO:0015749 monosaccharide transport 1 11 0 0.0200639 GO:0015758 glucose transport 2 120 0.2 0.0203542 GO:0006091 energy pathways 4 586 1 0.0211918 GO:0016773 phosphotransferase activity, alcohol group as acceptor 1 12 0 0.0218685 GO:0004179 membrane alanyl aminopeptidase activity 1 12 0 0.0218685 GO:0016284 alanine aminopeptidase activity 1 13 0 0.02367 GO:0019395 fatty acid oxidation 1 13 0 0.02367 GO:0045121 lipid raft 1 14 0 0.0254683 GO:0005924 cell-substrate adherens junction 3 350 0.6 0.0257042 GO:0006629 lipid metabolism 2 136 0.2 0.0257049 GO:0016779 nucleotidyltransferase activity 1 15 0 0.0272634 GO:0004722 protein serine/threonine phosphatase activity 1 15 0 0.0272634 GO:0004759 serine esterase activity 1 15 0 0.0272634 GO:0008286 insulin receptor signaling pathway 2 141 0.2 0.0274828 GO:0000287 magnesium ion binding 1 16 0 0.0290553 GO:0006289 nucleotide-excision repair 1 16 0 0.0290553 GO:0030055 cell-matrix junction 1 18 0 0.0326296 GO:0007015 actin filament organization 6 1366 2.5 0.0343993 GO:0017076 purine nucleotide binding 6 1374 2.5 0.0352696 GO:0000166 nucleotide binding 1 20 0 0.0361913 GO:0004091 carboxylesterase activity 1 20 0 0.0361913 GO:0019200 carbohydrate kinase activity 1 21 0 0.0379674 GO:0006099 tricarboxylic acid cycle 1 21 0 0.0379674 GO:0008287 protein serine/threonine phosphatase complex 7 1795 3.3 0.0391326 GO:0016787 hydrolase activity 1 22 0 0.0397404 GO:0019901 protein kinase binding 1 24 0 0.0432769 GO:0019900 kinase binding 15 5553 10.2 0.0441787 GO:0005622 intracellular 1 25 0 0.0450404 GO:0009617 response to bacteria 2 185 0.3 0.0451206 GO:0006396 RNA processing 4 4555 8.3 0.0455366 u GO:0016020 membrane 4 749 1.3 0.0462703 GO:0016301 kinase activity 7 1874 3.4 0.0479027 GO:0046872 metal ion binding 2 3170 5.8 0.0481589 u GO:0007154 cell communication 1 27 0 0.0485581 GO:0008643 carbohydrate transport 1 28 0 0.0503123 GO:0004177 aminopeptidase activity 1 28 0 0.0503123 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1 2359 4.3 0.0536075 u GO:0004872 receptor activity 1 32 0 0.057298 GO:0005912 adherens junction 5 1161 2.1 0.0573971 GO:0006464 protein modification 8 2384 4.3 0.0588446 GO:0019538 protein metabolism 3 514 0.9 0.0670056 GO:0005856 cytoskeleton 3 517 0.9 0.067943 GO:0006950 response to stress 2 2958 5.4 0.0680952 u GO:0004871 signal transducer activity 2 238 0.4 0.0704929 GO:0016070 RNA metabolism 1 42 0 0.0745467 GO:0030145 manganese ion binding 1 43 0 0.0762548 GO:0006790 sulfur metabolism 2 264 0.4 0.0843123 GO:0016567 protein ubiquitination 1 48 0 0.0847498 GO:0006096 glycolysis 1 48 0 0.0847498 GO:0008235 metalloexopeptidase activity 2 268 0.4 0.0865085 GO:0000151 ubiquitin ligase complex 1 51 0 0.0898108 GO:0005941 unlocalized 1 2048 3.7 0.0920066 u GO:0050789 regulation of biological process 1 53 0 0.0931697 GO:0019899 enzyme binding 2 280 0.5 0.093202 GO:0005794 Golgi apparatus 3 594 1 0.0940413 GO:0016788 hydrolase activity, acting on ester bonds 1 54 0 0.0948448 GO:0005777 peroxisome 1 54 0 0.0948448 GO:0042579 microbody 3 599 1.1 0.0958658 GO:0016491 oxidoreductase activity 1 55 0.1 0.0965168 GO:0007160 cell-matrix adhesion 2 2728 5 0.0974515 u GO:0007165 signal transduction 1 56 0.1 0.0981859 GO:0006007 glucose catabolism 1 57 0.1 0.099852 GO:0019320 hexose catabolism 1 57 0.1 0.099852 GO:0046164 alcohol catabolism 1 57 0.1 0.099852 GO:0046365 monosaccharide catabolism 2 293 0.5 0.100622 GO:0005975 carbohydrate metabolism 5 1372 2.5 0.10148 GO:0016740 transferase activity 8 2707 4.9 0.108142 GO:0005737 cytoplasm 3 632 1.1 0.108278 GO:0005739 mitochondrion 2 307 0.5 0.108796 GO:0004842 ubiquitin-protein ligase activity 1 63 0.1 0.109787 GO:0030036 actin cytoskeleton organization and biogenesis 1 64 0.1 0.111432 GO:0016052 carbohydrate catabolism 1 1922 3.5 0.11353 u GO:0007166 cell surface receptor linked signal transduction 1 67 0.1 0.116351 GO:0030029 actin filament-based process 2 326 0.5 0.120169 GO:0016881 acid-D-amino acid ligase activity 3 669 1.2 0.122924 GO:0006793 phosphorus metabolism 3 669 1.2 0.122924 GO:0006796 phosphate metabolism 1 73 0.1 0.126111 GO:0005875 microtubule associated complex 2 337 0.6 0.126889 GO:0006118 electron transport 1 74 0.1 0.127727 GO:0001501 skeletal development 1 74 0.1 0.127727 GO:0005516 calmodulin binding 1 75 0.1 0.129341 GO:0006006 glucose metabolism 1 75 0.1 0.129341 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 2 345 0.6 0.131834 GO:0004674 protein serine/threonine kinase activity 2 358 0.6 0.139967 GO:0015031 protein transport 2 360 0.6 0.141228 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1 83 0.1 0.142147 GO:0008238 exopeptidase activity 1 83 0.1 0.142147 GO:0016789 carboxylic ester hydrolase activity 2 368 0.6 0.1463 GO:0006512 ubiquitin cycle 1 86 0.1 0.146902 GO:0006725 aromatic compound metabolism 2 375 0.6 0.15077 GO:0003723 RNA binding 1 90 0.1 0.153203 GO:0008047 enzyme activator activity 1 91 0.1 0.154771 GO:0019318 hexose metabolism 1 92 0.1 0.156337 GO:0005083 small GTPase regulatory/interacting protein activity 1 92 0.1 0.156337 GO:0006631 fatty acid metabolism 2 384 0.7 0.15656 GO:0030234 enzyme regulator activity 1 93 0.1 0.157899 GO:0005996 monosaccharide metabolism 1 95 0.1 0.161016 GO:0007283 spermatogenesis 1 95 0.1 0.161016 GO:0048232 male gamete generation 1 96 0.1 0.162571 GO:0005911 intercellular junction 1 97 0.1 0.164122 GO:0006397 mRNA processing 1 97 0.1 0.164122 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6 2064 3.7 0.16917 GO:0005515 protein binding 1 103 0.1 0.173374 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1 106 0.1 0.177963 GO:0016071 mRNA metabolism 4 1221 2.2 0.182664 GO:0046914 transition metal ion binding 1 110 0.2 0.184043 GO:0006470 protein amino acid dephosphorylation 1 111 0.2 0.185556 GO:0016327 apicolateral plasma membrane 1 112 0.2 0.187067 GO:0016311 dephosphorylation 1 1606 2.9 0.187858 u GO:0050791 regulation of physiological process 1 118 0.2 0.196074 GO:0000278 mitotic cell cycle 1 118 0.2 0.196074 GO:0007167 enzyme linked receptor protein signaling pathway 1 119 0.2 0.197566 GO:0007243 protein kinase cascade 1 119 0.2 0.197566 GO:0030054 cell junction 1 1564 2.8 0.200322 u GO:0019222 regulation of metabolism 1 125 0.2 0.206461 GO:0006281 DNA repair 2 460 0.8 0.206973 GO:0016874 ligase activity 1 128 0.2 0.210873 GO:0004721 phosphoprotein phosphatase activity 1 130 0.2 0.213801 GO:0015629 actin cytoskeleton 1 131 0.2 0.215261 GO:0003774 motor activity 1 138 0.2 0.22541 GO:0015630 microtubule cytoskeleton 1 139 0.2 0.226849 GO:0030695 GTPase regulator activity 2 496 0.9 0.231518 GO:0004672 protein kinase activity 1 1458 2.6 0.234875 u GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 1452 2.6 0.236969 u GO:0045449 regulation of transcription 2 509 0.9 0.240445 GO:0006468 protein amino acid phosphorylation 1 149 0.2 0.241103 GO:0006974 response to DNA damage stimulus 1 1417 2.6 0.249488 u GO:0006351 transcription, DNA-dependent 1 157 0.2 0.252324 GO:0004252 serine-type endopeptidase activity 1 157 0.2 0.252324 GO:0009719 response to endogenous stimulus 1 158 0.2 0.253715 GO:0008237 metallopeptidase activity 1 159 0.2 0.255104 GO:0006066 alcohol metabolism 1 1393 2.5 0.258378 u GO:0006355 regulation of transcription, DNA-dependent 4 1415 2.6 0.25983 GO:0007275 development 1 166 0.3 0.264756 GO:0006457 protein folding 1 169 0.3 0.268856 GO:0008236 serine-type peptidase activity 2 559 1 0.274947 GO:0016310 phosphorylation 1 178 0.3 0.281024 GO:0007276 gametogenesis 4 3131 5.7 0.285975 u GO:0050875 cellular physiological process 1 187 0.3 0.292998 GO:0016791 phosphoric monoester hydrolase activity 2 590 1 0.296376 GO:0006508 proteolysis and peptidolysis 3 1058 1.9 0.308216 GO:0050896 response to stimulus 1 200 0.3 0.309954 GO:0005829 cytosol 2 610 1.1 0.310178 GO:0030163 protein catabolism 2 613 1.1 0.312246 GO:0009057 macromolecule catabolism 1 203 0.3 0.313812 GO:0000003 reproduction 1 203 0.3 0.313812 GO:0019953 sexual reproduction 1 204 0.3 0.315093 GO:0007010 cytoskeleton organization and biogenesis 2 622 1.1 0.318442 GO:0008233 peptidase activity 1 211 0.3 0.323996 GO:0004518 nuclease activity 3 1095 2 0.32739 GO:0008270 zinc ion binding 1 235 0.4 0.353686 GO:0009613 response to pest/pathogen/parasite 1 243 0.4 0.363301 GO:0042578 phosphoric ester hydrolase activity 1 244 0.4 0.364493 GO:0006996 organelle organization and biogenesis 2 698 1.2 0.370268 GO:0009887 organogenesis 1 259 0.4 0.38212 GO:0007399 neurogenesis 1 262 0.4 0.385588 GO:0019752 carboxylic acid metabolism 1 265 0.4 0.389038 GO:0006082 organic acid metabolism 4 2750 5 0.409648 u GO:0008151 cell growth and/or maintenance 1 286 0.5 0.41267 GO:0007028 cytoplasm organization and biogenesis 16 9173 16.8 0.430143 u GO:0005623 cell 4 2670 4.9 0.438461 u GO:0005634 nucleus 2 822 1.5 0.451648 GO:0009653 morphogenesis 1 327 0.6 0.456301 GO:0005783 endoplasmic reticulum 2 1516 2.7 0.461005 u GO:0006350 transcription 1 884 1.6 0.509696 u GO:0050874 organismal physiological process 1 879 1.6 0.512756 u GO:0009605 response to external stimulus 1 390 0.7 0.517328 GO:0007155 cell adhesion 4 2374 4.3 0.550857 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 433 0.7 0.555139 GO:0005102 receptor binding 5 2672 4.9 0.56227 GO:0003676 nucleic acid binding 1 456 0.8 0.574178 GO:0004175 endopeptidase activity 3 1604 2.9 0.579178 GO:0003677 DNA binding 1 491 0.9 0.601654 GO:0007049 cell cycle 1 500 0.9 0.608439 GO:0005509 calcium ion binding 1 505 0.9 0.61216 GO:0006259 DNA metabolism 1 723 1.3 0.612953 u GO:0005576 extracellular 3 1656 3 0.636244 u GO:0006810 transport 1 660 1.2 0.655514 u GO:0007242 intracellular signaling cascade 1 634 1.1 0.67331 u GO:0005886 plasma membrane 1 625 1.1 0.679494 u GO:0005198 structural molecule activity 1 619 1.1 0.683622 u GO:0008283 cell proliferation 1 582 1 0.709151 u GO:0016043 cell organization and biogenesis 1 578 1 0.711916 u GO:0009607 response to biotic stimulus