# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 62 #b referenced loci : 61 #c annotated loci : 46 #d hyper-geometric : n 46 hgN 14129 #e k hgK Exp k p-value term description 10 797 2.5 0.000196623 GO:0009056 catabolism 31 5837 19 0.00031042 GO:0008152 metabolism 2 21 0 0.00209353 GO:0006099 tricarboxylic acid cycle 3 88 0.2 0.00292084 GO:0006092 main pathways of carbohydrate metabolism 1 1 0 0.00325572 GO:0016034 maleylacetoacetate isomerase activity 1 1 0 0.00325572 GO:0045023 G0 to G1 transition 1 1 0 0.00325572 GO:0046208 spermine catabolism 1 1 0 0.00325572 GO:0047372 acylglycerol lipase activity 6 460 1.4 0.00357953 GO:0016874 ligase activity 24 4537 14.7 0.00371125 GO:0003824 catalytic activity 2 29 0 0.00398105 GO:0009310 amine catabolism 7 632 2 0.00405768 GO:0005739 mitochondrion 10 5831 18.9 0.00431161 u GO:0009987 cellular process 27 5553 18 0.00597337 GO:0005622 intracellular 3 114 0.3 0.0060347 GO:0015980 energy derivation by oxidation of organic compounds 1 2 0 0.00650106 GO:0000209 protein polyubiquitination 1 2 0 0.00650106 GO:0004020 adenylyl-sulfate kinase activity 1 2 0 0.00650106 GO:0004776 succinate-CoA ligase (GDP-forming) activity 1 2 0 0.00650106 GO:0004779 sulfate adenylyltransferase activity 1 2 0 0.00650106 GO:0004781 sulfate adenylyltransferase (ATP) activity 1 2 0 0.00650106 GO:0006598 polyamine catabolism 1 2 0 0.00650106 GO:0042177 negative regulation of protein catabolism 1 2 0 0.00650106 GO:0046592 polyamine oxidase activity 5 368 1.1 0.00665738 GO:0006512 ubiquitin cycle 3 120 0.3 0.0069531 GO:0006091 energy pathways 3 2958 9.6 0.00738477 u GO:0004871 signal transducer activity 7 4555 14.8 0.00744227 u GO:0016020 membrane 1 3 0 0.00973607 GO:0000320 re-entry into mitotic cell cycle 1 3 0 0.00973607 GO:0004652 polynucleotide adenylyltransferase activity 1 3 0 0.00973607 GO:0004774 succinate-CoA ligase activity 1 3 0 0.00973607 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor 1 3 0 0.00973607 GO:0043149 stress fiber formation 1 3 0 0.00973607 GO:0048041 focal adhesion formation 1 1922 6.2 0.0098027 u GO:0007166 cell surface receptor linked signal transduction 4 264 0.8 0.0105108 GO:0016567 protein ubiquitination 2 48 0.1 0.0106355 GO:0006096 glycolysis 4 268 0.8 0.0110618 GO:0000151 ubiquitin ligase complex 2 2359 7.6 0.0115155 u GO:0004872 receptor activity 2 51 0.1 0.0119475 GO:0016042 lipid catabolism 31 7041 22.9 0.0121018 GO:0005488 binding 6 599 1.9 0.0125402 GO:0016491 oxidoreductase activity 1 4 0 0.0129608 GO:0000103 sulfate assimilation 1 4 0 0.0129608 GO:0003997 acyl-CoA oxidase activity 1 4 0 0.0129608 GO:0004449 isocitrate dehydrogenase (NAD+) activity 1 4 0 0.0129608 GO:0006791 sulfur utilization 1 4 0 0.0129608 GO:0009895 negative regulation of catabolism 1 4 0 0.0129608 GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors 35 8414 27.3 0.0142266 GO:0007582 physiological process 2 56 0.1 0.0142832 GO:0006007 glucose catabolism 2 57 0.1 0.0147722 GO:0019320 hexose catabolism 2 57 0.1 0.0147722 GO:0046164 alcohol catabolism 2 57 0.1 0.0147722 GO:0046365 monosaccharide catabolism 1 5 0 0.0161752 GO:0004287 prolyl oligopeptidase activity 1 5 0 0.0161752 GO:0004396 hexokinase activity 1 5 0 0.0161752 GO:0006572 tyrosine catabolism 4 307 0.9 0.0174316 GO:0004842 ubiquitin-protein ligase activity 2 64 0.2 0.0183933 GO:0016052 carbohydrate catabolism 1 6 0 0.0193794 GO:0001725 stress fiber 1 6 0 0.0193794 GO:0004448 isocitrate dehydrogenase activity 1 6 0 0.0193794 GO:0006559 phenylalanine catabolism 1 6 0 0.0193794 GO:0008215 spermine metabolism 1 6 0 0.0193794 GO:0042176 regulation of protein catabolism 4 326 1 0.0212238 GO:0016881 acid-D-amino acid ligase activity 1 7 0 0.0225734 GO:0006558 L-phenylalanine metabolism 1 7 0 0.0225734 GO:0009074 aromatic amino acid family catabolism 1 7 0 0.0225734 GO:0016405 CoA-ligase activity 1 7 0 0.0225734 GO:0016878 acid-thiol ligase activity 1 7 0 0.0225734 GO:0042402 biogenic amine catabolism 1 7 0 0.0225734 GO:0051017 actin filament bundle formation 4 337 1 0.023635 GO:0006118 electron transport 2 74 0.2 0.0241432 GO:0005516 calmodulin binding 2 75 0.2 0.024754 GO:0006006 glucose metabolism 1 8 0 0.0257572 GO:0006635 fatty acid beta-oxidation 1 8 0 0.0257572 GO:0019905 syntaxin binding 1 8 0 0.0257572 GO:0042219 amino acid derivative catabolism 1 9 0 0.0289308 GO:0000086 G2/M transition of mitotic cell cycle 1 9 0 0.0289308 GO:0000781 chromosome, telomeric region 1 9 0 0.0289308 GO:0007004 telomerase-dependent telomere maintenance 1 9 0 0.0289308 GO:0009618 response to pathogenic bacteria 1 9 0 0.0289308 GO:0009894 regulation of catabolism 1 9 0 0.0289308 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1 9 0 0.0289308 GO:0019439 aromatic compound catabolism 4 360 1.1 0.029201 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2 86 0.2 0.031879 GO:0006725 aromatic compound metabolism 1 10 0 0.0320944 GO:0005913 cell-cell adherens junction 1 10 0 0.0320944 GO:0016358 dendrite morphogenesis 8 1161 3.7 0.0321381 GO:0006464 protein modification 2 90 0.2 0.0346478 GO:0008047 enzyme activator activity 11 1874 6.1 0.0349565 GO:0046872 metal ion binding 1 11 0 0.0352478 GO:0000149 SNARE binding 1 11 0 0.0352478 GO:0004602 glutathione peroxidase activity 1 11 0 0.0352478 GO:0005158 insulin receptor binding 1 11 0 0.0352478 GO:0006595 polyamine metabolism 1 11 0 0.0352478 GO:0007586 digestion 1 11 0 0.0352478 GO:0008645 hexose transport 1 11 0 0.0352478 GO:0015749 monosaccharide transport 1 11 0 0.0352478 GO:0015758 glucose transport 2 91 0.2 0.0353542 GO:0019318 hexose metabolism 5 3170 10.3 0.0366303 u GO:0007154 cell communication 2 93 0.3 0.0367838 GO:0005996 monosaccharide metabolism 13 2384 7.7 0.0369258 GO:0019538 protein metabolism 1 12 0 0.0383912 GO:0000315 organellar large ribosomal subunit 1 12 0 0.0383912 GO:0004179 membrane alanyl aminopeptidase activity 1 12 0 0.0383912 GO:0005762 mitochondrial large ribosomal subunit 1 12 0 0.0383912 GO:0006570 tyrosine metabolism 1 12 0 0.0383912 GO:0016284 alanine aminopeptidase activity 1 13 0 0.0415246 GO:0016877 ligase activity, forming carbon-sulfur bonds 1 13 0 0.0415246 GO:0019395 fatty acid oxidation 1 13 0 0.0415246 GO:0045121 lipid raft 8 1221 3.9 0.0415536 GO:0046914 transition metal ion binding 4 2728 8.8 0.0419254 u GO:0007165 signal transduction 1 14 0 0.044648 GO:0000723 telomere maintenance 1 14 0 0.044648 GO:0005924 cell-substrate adherens junction 1 15 0 0.0477614 GO:0004722 protein serine/threonine phosphatase activity 1 15 0 0.0477614 GO:0004759 serine esterase activity 1 15 0 0.0477614 GO:0008286 insulin receptor signaling pathway 1 16 0 0.050865 GO:0006289 nucleotide-excision repair 1 16 0 0.050865 GO:0030055 cell-matrix junction 1 18 0 0.0570423 GO:0007015 actin filament organization 1 18 0 0.0570423 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1 19 0 0.0601162 GO:0000313 organellar ribosome 1 19 0 0.0601162 GO:0005761 mitochondrial ribosome 1 19 0 0.0601162 GO:0009072 aromatic amino acid family metabolism 7 1095 3.5 0.062188 GO:0008270 zinc ion binding 1 20 0 0.0631804 GO:0004091 carboxylesterase activity 1 20 0 0.0631804 GO:0019200 carbohydrate kinase activity 11 2064 6.7 0.0635042 GO:0005515 protein binding 1 21 0 0.0662347 GO:0004129 cytochrome-c oxidase activity 1 21 0 0.0662347 GO:0008287 protein serine/threonine phosphatase complex 1 21 0 0.0662347 GO:0015002 heme-copper terminal oxidase activity 1 21 0 0.0662347 GO:0016675 oxidoreductase activity, acting on heme group of donors 1 21 0 0.0662347 GO:0016676 oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 1 21 0 0.0662347 GO:0043087 regulation of GTPase activity 1 22 0 0.0692793 GO:0004364 glutathione transferase activity 1 22 0 0.0692793 GO:0019901 protein kinase binding 3 293 0.9 0.0697867 GO:0005975 carbohydrate metabolism 1 23 0 0.0723142 GO:0009063 amino acid catabolism 2 136 0.4 0.072341 GO:0016779 nucleotidyltransferase activity 2 139 0.4 0.0751238 GO:0030695 GTPase regulator activity 1 24 0 0.0753394 GO:0019900 kinase binding 2 141 0.4 0.076998 GO:0000287 magnesium ion binding 1 25 0 0.0783549 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1 25 0 0.0783549 GO:0009617 response to bacteria 1 27 0 0.0843572 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1 27 0 0.0843572 GO:0005759 mitochondrial matrix 1 27 0 0.0843572 GO:0008643 carbohydrate transport 1 27 0 0.0843572 GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity 2 149 0.4 0.0846416 GO:0006974 response to DNA damage stimulus 4 514 1.6 0.085298 GO:0005856 cytoskeleton 4 517 1.6 0.0867107 GO:0006950 response to stress 1 28 0 0.087344 GO:0004177 aminopeptidase activity 1 28 0 0.087344 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 13 2707 8.8 0.0874307 GO:0005737 cytoplasm 6 3131 10.1 0.0893695 u GO:0050875 cellular physiological process 1 29 0 0.0903212 GO:0015934 large ribosomal subunit 2 157 0.5 0.0925076 GO:0009719 response to endogenous stimulus 2 159 0.5 0.094507 GO:0006066 alcohol metabolism 1 32 0.1 0.0991961 GO:0005912 adherens junction 1 32 0.1 0.0991961 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2 167 0.5 0.102629 GO:0006519 amino acid and derivative metabolism 1 1147 3.7 0.102682 u GO:0005215 transporter activity 5 771 2.5 0.104151 GO:0016772 transferase activity, transferring phosphorus-containing groups 1 34 0.1 0.105066 GO:0016859 cis-trans isomerase activity 3 350 1.1 0.105097 GO:0006629 lipid metabolism 1 37 0.1 0.1138 GO:0006576 biogenic amine metabolism 1 38 0.1 0.116692 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2 181 0.5 0.117283 GO:0009308 amine metabolism 2 185 0.6 0.121565 GO:0006396 RNA processing 4 586 1.9 0.12229 GO:0016773 phosphotransferase activity, alcohol group as acceptor 3 375 1.2 0.12245 GO:0003723 RNA binding 1 41 0.1 0.125315 GO:0003682 chromatin binding 4 594 1.9 0.126778 GO:0016788 hydrolase activity, acting on ester bonds 1 42 0.1 0.128172 GO:0030145 manganese ion binding 3 384 1.2 0.128945 GO:0030234 enzyme regulator activity 6 1067 3.4 0.130613 GO:0005524 ATP binding 1 43 0.1 0.131018 GO:0006790 sulfur metabolism 1 44 0.1 0.133856 GO:0000122 negative regulation of transcription from Pol II promoter 6 1078 3.5 0.135303 GO:0030554 adenyl nucleotide binding 4 610 1.9 0.135966 GO:0030163 protein catabolism 1 45 0.1 0.136685 GO:0006575 amino acid derivative metabolism 4 613 1.9 0.137719 GO:0009057 macromolecule catabolism 1 48 0.1 0.145117 GO:0008235 metalloexopeptidase activity 1 50 0.1 0.150694 GO:0050790 regulation of enzyme activity 7 1366 4.4 0.151698 GO:0017076 purine nucleotide binding 1 51 0.1 0.153468 GO:0005941 unlocalized 7 1374 4.4 0.155002 GO:0000166 nucleotide binding 1 53 0.1 0.158992 GO:0019899 enzyme binding 1 54 0.1 0.16174 GO:0005777 peroxisome 1 54 0.1 0.16174 GO:0042579 microbody 1 55 0.1 0.16448 GO:0007160 cell-matrix adhesion 1 59 0.1 0.175351 GO:0008081 phosphoric diester hydrolase activity 2 238 0.7 0.181362 GO:0016070 RNA metabolism 6 2750 8.9 0.181528 u GO:0008151 cell growth and/or maintenance 1 62 0.2 0.183413 GO:0004840 ubiquitin conjugating enzyme activity 1 62 0.2 0.183413 GO:0005096 GTPase activator activity 1 62 0.2 0.183413 GO:0008639 small protein conjugating enzyme activity 1 63 0.2 0.186084 GO:0030036 actin cytoskeleton organization and biogenesis 2 243 0.7 0.187229 GO:0042578 phosphoric ester hydrolase activity 3 1656 5.3 0.196332 u GO:0006810 transport 1 67 0.2 0.19668 GO:0030029 actin filament-based process 1 67 0.2 0.19668 GO:0045892 negative regulation of transcription, DNA-dependent 2 262 0.8 0.209757 GO:0019752 carboxylic acid metabolism 1 73 0.2 0.212321 GO:0005875 microtubule associated complex 2 265 0.8 0.213343 GO:0006082 organic acid metabolism 1 872 2.8 0.214394 u GO:0009058 biosynthesis 1 74 0.2 0.214899 GO:0001501 skeletal development 1 75 0.2 0.217468 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 8 1795 5.8 0.223489 GO:0016787 hydrolase activity 4 749 2.4 0.225821 GO:0016301 kinase activity 2 276 0.8 0.226543 GO:0030529 ribonucleoprotein complex 2 280 0.9 0.23136 GO:0005794 Golgi apparatus 1 81 0.2 0.232714 GO:0005743 mitochondrial inner membrane 1 83 0.2 0.23773 GO:0008238 exopeptidase activity 1 83 0.2 0.23773 GO:0016789 carboxylic ester hydrolase activity 5 1058 3.4 0.259695 GO:0050896 response to stimulus 1 92 0.2 0.259912 GO:0005083 small GTPase regulatory/interacting protein activity 1 92 0.2 0.259912 GO:0006631 fatty acid metabolism 7 1604 5.2 0.2632 GO:0003677 DNA binding 1 95 0.3 0.267165 GO:0007283 spermatogenesis 1 95 0.3 0.267165 GO:0048232 male gamete generation 1 96 0.3 0.269567 GO:0005911 intercellular junction 1 97 0.3 0.271961 GO:0006397 mRNA processing 1 97 0.3 0.271961 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1 100 0.3 0.279098 GO:0015078 hydrogen ion transporter activity 1 102 0.3 0.283818 GO:0006511 ubiquitin-dependent protein catabolism 1 102 0.3 0.283818 GO:0019866 inner membrane 1 102 0.3 0.283818 GO:0019941 modification-dependent protein catabolism 1 103 0.3 0.286167 GO:0015077 monovalent inorganic cation transporter activity 1 103 0.3 0.286167 GO:0016481 negative regulation of transcription 1 103 0.3 0.286167 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 6 1372 4.4 0.286316 GO:0016740 transferase activity 1 106 0.3 0.293168 GO:0016071 mRNA metabolism 1 107 0.3 0.295486 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 109 0.3 0.300101 GO:0005740 mitochondrial membrane 3 590 1.9 0.301359 GO:0006508 proteolysis and peptidolysis 1 110 0.3 0.302398 GO:0006470 protein amino acid dephosphorylation 1 111 0.3 0.304687 GO:0016327 apicolateral plasma membrane 1 112 0.3 0.306968 GO:0006357 regulation of transcription from Pol II promoter 1 112 0.3 0.306968 GO:0016311 dephosphorylation 1 724 2.3 0.309458 u GO:0009059 macromolecule biosynthesis 2 345 1.1 0.310067 GO:0004674 protein serine/threonine kinase activity 1 723 2.3 0.310201 u GO:0005576 extracellular 1 118 0.3 0.320505 GO:0000278 mitotic cell cycle 1 118 0.3 0.320505 GO:0007167 enzyme linked receptor protein signaling pathway 1 119 0.3 0.322736 GO:0007243 protein kinase cascade 1 119 0.3 0.322736 GO:0030054 cell junction 2 358 1.1 0.325729 GO:0015031 protein transport 1 121 0.3 0.327176 GO:0016853 isomerase activity 3 625 2 0.332914 GO:0005198 structural molecule activity 1 125 0.4 0.335972 GO:0006281 DNA repair 1 127 0.4 0.340327 GO:0009892 negative regulation of metabolism 1 128 0.4 0.342494 GO:0004721 phosphoprotein phosphatase activity 1 130 0.4 0.346808 GO:0015629 actin cytoskeleton 1 131 0.4 0.348954 GO:0003774 motor activity 1 131 0.4 0.348954 GO:0015399 primary active transporter activity 1 132 0.4 0.351094 GO:0006520 amino acid metabolism 1 660 2.1 0.359892 u GO:0007242 intracellular signaling cascade 1 138 0.4 0.363787 GO:0015630 microtubule cytoskeleton 2 390 1.2 0.363895 GO:0007155 cell adhesion 6 1516 4.9 0.37185 GO:0006350 transcription 3 669 2.1 0.372585 GO:0006793 phosphorus metabolism 3 669 2.1 0.372585 GO:0006796 phosphate metabolism 1 146 0.4 0.380334 GO:0006366 transcription from Pol II promoter 1 634 2 0.382085 u GO:0005886 plasma membrane 1 157 0.5 0.4024 GO:0004252 serine-type endopeptidase activity 1 158 0.5 0.404367 GO:0008237 metallopeptidase activity 1 166 0.5 0.419881 GO:0005840 ribosome 1 166 0.5 0.419881 GO:0006457 protein folding 1 169 0.5 0.425596 GO:0008236 serine-type peptidase activity 1 170 0.5 0.427488 GO:0008324 cation transporter activity 1 178 0.5 0.442412 GO:0007276 gametogenesis 2 884 2.8 0.444119 u GO:0050874 organismal physiological process 1 181 0.5 0.44791 GO:0007001 chromosome organization and biogenesis (sensu Eukarya) 2 879 2.8 0.448054 u GO:0009605 response to external stimulus 29 9173 29.8 0.44912 u GO:0005623 cell 1 187 0.6 0.458747 GO:0006997 nuclear organization and biogenesis 1 187 0.6 0.458747 GO:0016791 phosphoric monoester hydrolase activity 1 198 0.6 0.478077 GO:0000074 regulation of cell cycle 2 491 1.5 0.478326 GO:0007049 cell cycle 1 199 0.6 0.4798 GO:0003735 structural constituent of ribosome 5 1393 4.5 0.479935 GO:0006355 regulation of transcription, DNA-dependent 1 200 0.6 0.481518 GO:0005829 cytosol 2 496 1.6 0.483686 GO:0004672 protein kinase activity 1 203 0.6 0.486638 GO:0000003 reproduction 1 203 0.6 0.486638 GO:0019953 sexual reproduction 1 204 0.6 0.488334 GO:0007010 cytoskeleton organization and biogenesis 6 2048 6.6 0.492036 u GO:0050789 regulation of biological process 2 822 2.6 0.494221 u GO:0009653 morphogenesis 5 1417 4.6 0.495492 GO:0006351 transcription, DNA-dependent 1 209 0.6 0.496731 GO:0005694 chromosome 2 509 1.6 0.497469 GO:0006468 protein amino acid phosphorylation 1 211 0.6 0.500051 GO:0004518 nuclease activity 4 1415 4.6 0.505799 u GO:0007275 development 1 505 1.6 0.506748 u GO:0006259 DNA metabolism 1 500 1.6 0.512049 u GO:0005509 calcium ion binding 9 2670 8.6 0.513236 GO:0005634 nucleus 9 2672 8.6 0.514221 GO:0003676 nucleic acid binding 5 1452 4.7 0.517905 GO:0045449 regulation of transcription 8 2374 7.7 0.518458 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 224 0.7 0.52112 GO:0015075 ion transporter activity 5 1458 4.7 0.521711 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 2 776 2.5 0.533064 u GO:0030528 transcription regulator activity 1 480 1.5 0.533579 u GO:0006952 defense response 1 235 0.7 0.538267 GO:0009613 response to pest/pathogen/parasite 2 559 1.8 0.548337 GO:0016310 phosphorylation 1 244 0.7 0.551849 GO:0006996 organelle organization and biogenesis 1 456 1.4 0.560068 u GO:0004175 endopeptidase activity 2 578 1.8 0.56674 GO:0009607 response to biotic stimulus 2 582 1.8 0.570547 GO:0016043 cell organization and biogenesis 1 444 1.4 0.573564 u GO:0006412 protein biosynthesis 5 1606 5.2 0.57359 u GO:0050791 regulation of physiological process 1 259 0.8 0.573621 GO:0007399 neurogenesis 2 596 1.9 0.583691 GO:0003700 transcription factor activity 1 433 1.4 0.586074 u GO:0005102 receptor binding 5 1564 5 0.599062 u GO:0019222 regulation of metabolism 1 420 1.3 0.60102 u GO:0006955 immune response 2 698 2.2 0.601439 u GO:0009887 organogenesis 1 286 0.9 0.610232 GO:0005525 GTP binding 1 286 0.9 0.610232 GO:0007028 cytoplasm organization and biogenesis 1 294 0.9 0.620477 GO:0019001 guanyl nucleotide binding 2 622 2 0.669795 u GO:0008233 peptidase activity 2 619 2 0.672503 u GO:0008283 cell proliferation 1 346 1.1 0.688726 u GO:0016265 death 1 343 1.1 0.692349 u GO:0008219 cell death 1 327 1 0.711714 u GO:0005783 endoplasmic reticulum 1 313 1 0.728694 u GO:0012501 programmed cell death 1 311 1 0.73112 u GO:0005386 carrier activity 1 309 1 0.733546 u GO:0006915 apoptosis