# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 75 #b referenced loci : 72 #c annotated loci : 65 #d hyper-geometric : n 65 hgN 14129 #e k hgK Exp k p-value term description 10 514 2.3 0.00011009 GO:0005856 cytoskeleton 2 6 0 0.000308903 GO:0019894 kinesin binding 4 73 0.3 0.000349921 GO:0005875 microtubule associated complex 4 74 0.3 0.000368646 GO:0005516 calmodulin binding 5 138 0.6 0.000426651 GO:0015630 microtubule cytoskeleton 20 2064 9.4 0.000683672 GO:0005515 protein binding 45 7041 32.3 0.00117554 GO:0005488 binding 3 49 0.2 0.00147215 GO:0005789 endoplasmic reticulum membrane 3 50 0.2 0.001561 GO:0042175 nuclear envelope-endoplasmic reticulum network 10 749 3.4 0.00209179 GO:0016301 kinase activity 3 2359 10.8 0.00308185 u GO:0004872 receptor activity 12 1067 4.9 0.00310284 GO:0005524 ATP binding 14 1366 6.2 0.00319787 GO:0017076 purine nucleotide binding 14 1374 6.3 0.00337331 GO:0000166 nucleotide binding 12 1078 4.9 0.00337468 GO:0030554 adenyl nucleotide binding 5 2958 13.6 0.00346277 u GO:0004871 signal transducer activity 22 2707 12.4 0.00359569 GO:0005737 cytoplasm 1 1597 7.3 0.00376349 u GO:0007186 G-protein coupled receptor protein signaling pathway 2 21 0 0.0041364 GO:0043087 regulation of GTPase activity 1 1 0 0.00460047 GO:0004438 phosphatidylinositol-3-phosphatase activity 1 1 0 0.00460047 GO:0004691 cAMP-dependent protein kinase activity 1 1 0 0.00460047 GO:0005955 calcineurin complex 1 1 0 0.00460047 GO:0007274 neuromuscular synaptic transmission 1 1 0 0.00460047 GO:0008089 anterograde axon cargo transport 1 1 0 0.00460047 GO:0016939 kinesin II complex 1 1 0 0.00460047 GO:0019987 negative regulation of anti-apoptosis 1 1 0 0.00460047 GO:0030325 adrenal gland development 2 1922 8.8 0.00461422 u GO:0007166 cell surface receptor linked signal transduction 6 345 1.5 0.00499409 GO:0004674 protein serine/threonine kinase activity 4 157 0.7 0.00587346 GO:0012505 endomembrane system 12 1161 5.3 0.00611451 GO:0006464 protein modification 36 5553 25.5 0.00615255 GO:0005622 intracellular 3 84 0.3 0.00679218 GO:0007017 microtubule-based process 7 496 2.2 0.00755952 GO:0004672 protein kinase activity 8 3552 16.3 0.00870403 u GO:0016021 integral to membrane 1 2 0 0.00918009 GO:0000209 protein polyubiquitination 1 2 0 0.00918009 GO:0001672 regulation of chromatin assembly/disassembly 1 2 0 0.00918009 GO:0004827 proline-tRNA ligase activity 1 2 0 0.00918009 GO:0006433 prolyl-tRNA aminoacylation 1 2 0 0.00918009 GO:0008250 oligosaccharyl transferase complex 1 2 0 0.00918009 GO:0018196 peptidyl-asparagine modification 1 2 0 0.00918009 GO:0018279 N-linked glycosylation via asparagine 1 2 0 0.00918009 GO:0030517 negative regulation of axon extension 1 2 0 0.00918009 GO:0045646 regulation of erythrocyte differentiation 1 2 0 0.00918009 GO:0045648 positive regulation of erythrocyte differentiation 8 669 3 0.0112969 GO:0006793 phosphorus metabolism 8 669 3 0.0112969 GO:0006796 phosphate metabolism 3 102 0.4 0.0115448 GO:0045202 synapse 2 38 0.1 0.0131695 GO:0007018 microtubule-based movement 2 38 0.1 0.0131695 GO:0030705 cytoskeleton-dependent intracellular transport 1 3 0 0.013739 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 1 3 0 0.013739 GO:0004690 cyclic nucleotide-dependent protein kinase activity 1 3 0 0.013739 GO:0004818 glutamate-tRNA ligase activity 1 3 0 0.013739 GO:0004828 serine-tRNA ligase activity 1 3 0 0.013739 GO:0005869 dynactin complex 1 3 0 0.013739 GO:0006424 glutamyl-tRNA aminoacylation 1 3 0 0.013739 GO:0006434 seryl-tRNA aminoacylation 2 39 0.1 0.0138406 GO:0006418 tRNA aminoacylation for protein translation 2 39 0.1 0.0138406 GO:0043038 amino acid activation 2 39 0.1 0.0138406 GO:0043039 tRNA aminoacylation 4 204 0.9 0.0143972 GO:0007010 cytoskeleton organization and biogenesis 2 41 0.1 0.0152263 GO:0004812 tRNA ligase activity 2 41 0.1 0.0152263 GO:0008452 RNA ligase activity 2 41 0.1 0.0152263 GO:0016875 ligase activity, forming carbon-oxygen bonds 2 41 0.1 0.0152263 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds 2 42 0.1 0.0159407 GO:0006400 tRNA modification 3 119 0.5 0.0174258 GO:0009790 embryonic development 7 586 2.6 0.0177112 GO:0016773 phosphotransferase activity, alcohol group as acceptor 1 4 0 0.0182772 GO:0001515 opioid peptide activity 1 4 0 0.0182772 GO:0007435 salivary gland morphogenesis 1 4 0 0.0182772 GO:0008088 axon cargo transport 1 4 0 0.0182772 GO:0045639 positive regulation of myeloid blood cell differentiation 1 4 0 0.0182772 GO:0045767 regulation of anti-apoptosis 6 460 2.1 0.0188667 GO:0016874 ligase activity 4 222 1 0.019043 GO:0008092 cytoskeletal protein binding 2 47 0.2 0.0197221 GO:0016886 ligase activity, forming phosphoric ester bonds 3 127 0.5 0.0206751 GO:0043037 translation 2 49 0.2 0.0213298 GO:0009451 RNA modification 2 50 0.2 0.0221535 GO:0050790 regulation of enzyme activity 3 131 0.6 0.0224165 GO:0003774 motor activity 1 5 0 0.0227949 GO:0000145 exocyst 1 5 0 0.0227949 GO:0004576 oligosaccharyl transferase activity 1 5 0 0.0227949 GO:0008717 D-alanyl-D-alanine endopeptidase activity 1 5 0 0.0227949 GO:0030516 regulation of axon extension 1 5 0 0.0227949 GO:0030865 cortical cytoskeleton organization and biogenesis 1 5 0 0.0227949 GO:0030866 cortical actin cytoskeleton organization and biogenesis 3 132 0.6 0.022864 GO:0006520 amino acid metabolism 4 244 1.1 0.0258621 GO:0006996 organelle organization and biogenesis 1 1147 5.2 0.0272254 u GO:0005215 transporter activity 1 6 0 0.0272921 GO:0001658 ureteric bud branching 1 6 0 0.0272921 GO:0001704 formation of primary germ layer 1 6 0 0.0272921 GO:0001707 mesoderm formation 1 6 0 0.0272921 GO:0007270 nerve-nerve synaptic transmission 1 6 0 0.0272921 GO:0007431 salivary gland development 1 6 0 0.0272921 GO:0042577 lipid phosphatase activity 1 6 0 0.0272921 GO:0048332 mesoderm morphogenesis 6 509 2.3 0.0292179 GO:0006468 protein amino acid phosphorylation 1 7 0 0.0317689 GO:0005388 calcium-transporting ATPase activity 1 7 0 0.0317689 GO:0006564 L-serine biosynthesis 1 7 0 0.0317689 GO:0015085 calcium ion transporter activity 2 62 0.2 0.0330182 GO:0004840 ubiquitin conjugating enzyme activity 2 62 0.2 0.0330182 GO:0008639 small protein conjugating enzyme activity 2 65 0.2 0.0360018 GO:0006399 tRNA metabolism 1 8 0 0.0362254 GO:0005871 kinesin complex 1 8 0 0.0362254 GO:0007595 lactation 1 8 0 0.0362254 GO:0030218 erythrocyte differentiation 1 8 0 0.0362254 GO:0030659 cytoplasmic vesicle membrane 17 2384 10.9 0.0384485 GO:0019538 protein metabolism 1 9 0 0.0406617 GO:0017124 SH3 domain binding 28 4537 20.8 0.0410885 GO:0003824 catalytic activity 2 70 0.3 0.0411956 GO:0006816 calcium ion transport 3 167 0.7 0.0415787 GO:0006519 amino acid and derivative metabolism 4 286 1.3 0.0425364 GO:0007028 cytoplasm organization and biogenesis 6 559 2.5 0.0430992 GO:0016310 phosphorylation 1 10 0 0.0450779 GO:0001763 branching morphogenesis 1 10 0 0.0450779 GO:0006563 L-serine metabolism 1 10 0 0.0450779 GO:0009070 serine family amino acid biosynthesis 1 11 0 0.0494741 GO:0001657 ureteric bud development 1 11 0 0.0494741 GO:0042472 inner ear morphogenesis 1 11 0 0.0494741 GO:0051052 regulation of DNA metabolism 3 181 0.8 0.0506925 GO:0009308 amine metabolism 4 307 1.4 0.0527123 GO:0004842 ubiquitin-protein ligase activity 1 12 0 0.0538504 GO:0006487 N-linked glycosylation 1 12 0 0.0538504 GO:0007189 G-protein signaling, adenylate cyclase activating pathway 1 12 0 0.0538504 GO:0042471 ear morphogenesis 1 13 0 0.0582068 GO:0005938 cell cortex 1 13 0 0.0582068 GO:0006446 regulation of translational initiation 1 13 0 0.0582068 GO:0007498 mesoderm development 1 13 0 0.0582068 GO:0007548 sex differentiation 1 13 0 0.0582068 GO:0016998 cell wall catabolism 1 13 0 0.0582068 GO:0042493 response to drug 4 321 1.4 0.0601759 GO:0046907 intracellular transport 1 14 0 0.0625435 GO:0006700 C21-steroid hormone biosynthesis 1 14 0 0.0625435 GO:0009069 serine family amino acid metabolism 1 14 0 0.0625435 GO:0012506 vesicle membrane 4 326 1.4 0.0629721 GO:0016881 acid-D-amino acid ligase activity 7 771 3.5 0.0630474 GO:0016772 transferase activity, transferring phosphorus-containing groups 4 327 1.5 0.0635395 GO:0005783 endoplasmic reticulum 1 15 0 0.0668605 GO:0004722 protein serine/threonine phosphatase activity 1 15 0 0.0668605 GO:0008207 C21-steroid hormone metabolism 1 15 0 0.0668605 GO:0008286 insulin receptor signaling pathway 1 15 0 0.0668605 GO:0045637 regulation of myeloid blood cell differentiation 1 16 0 0.071158 GO:0007059 chromosome segregation 1 16 0 0.071158 GO:0030176 integral to endoplasmic reticulum membrane 1 17 0 0.0754359 GO:0016323 basolateral plasma membrane 1 18 0 0.0796945 GO:0001656 metanephros development 1 18 0 0.0796945 GO:0001822 kidney development 1 18 0 0.0796945 GO:0004437 inositol/phosphatidylinositol phosphatase activity 1 18 0 0.0796945 GO:0042446 hormone biosynthesis 5 500 2.3 0.0797176 GO:0005509 calcium ion binding 1 879 4 0.0811908 u GO:0009605 response to external stimulus 4 360 1.6 0.0837691 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1 19 0 0.0839337 GO:0001655 urogenital system development 1 19 0 0.0839337 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 1 19 0 0.0839337 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 1 19 0 0.0839337 GO:0030286 dynein complex 21 5831 26.8 0.0881318 u GO:0009987 cellular process 1 20 0 0.0881537 GO:0007369 gastrulation 1 20 0 0.0881537 GO:0045597 positive regulation of cell differentiation 4 368 1.6 0.0891027 GO:0006512 ubiquitin cycle 2 110 0.5 0.0910981 GO:0015674 di-, tri-valent inorganic cation transport 1 21 0 0.0923546 GO:0000082 G1/S transition of mitotic cell cycle 1 21 0 0.0923546 GO:0008287 protein serine/threonine phosphatase complex 2 112 0.5 0.093916 GO:0006357 regulation of transcription from Pol II promoter 2 112 0.5 0.093916 GO:0016311 dephosphorylation 1 22 0.1 0.0965364 GO:0046982 protein heterodimerization activity 8 2728 12.5 0.0965633 u GO:0007165 signal transduction 3 243 1.1 0.101219 GO:0042578 phosphoric ester hydrolase activity 2 118 0.5 0.102518 GO:0000278 mitotic cell cycle 2 119 0.5 0.103973 GO:0007243 protein kinase cascade 1 24 0.1 0.104843 GO:0003777 microtubule motor activity 1 24 0.1 0.104843 GO:0006112 energy reserve metabolism 1 24 0.1 0.104843 GO:0015082 di-, tri-valent inorganic cation transporter activity 1 24 0.1 0.104843 GO:0019933 cAMP-mediated signaling 2 122 0.5 0.108371 GO:0007268 synaptic transmission 1 25 0.1 0.108968 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1 25 0.1 0.108968 GO:0008017 microtubule binding 16 4555 20.9 0.116492 u GO:0016020 membrane 1 27 0.1 0.117163 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1 27 0.1 0.117163 GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity 2 128 0.5 0.117312 GO:0004721 phosphoprotein phosphatase activity 2 128 0.5 0.117312 GO:0019226 transmission of nerve impulse 2 128 0.5 0.117312 GO:0050905 neuromuscular physiological process 3 262 1.2 0.119627 GO:0019752 carboxylic acid metabolism 1 28 0.1 0.121232 GO:0019935 cyclic-nucleotide-mediated signaling 3 265 1.2 0.122642 GO:0006082 organic acid metabolism 3 270 1.2 0.127729 GO:0005578 extracellular matrix 5 582 2.6 0.129148 GO:0016043 cell organization and biogenesis 1 30 0.1 0.129315 GO:0015631 tubulin binding 1 31 0.1 0.133329 GO:0050876 reproductive physiological process 1 32 0.1 0.137325 GO:0018193 peptidyl-amino acid modification 1 32 0.1 0.137325 GO:0019904 protein domain specific binding 1 33 0.1 0.141303 GO:0003702 RNA polymerase II transcription factor activity 1 33 0.1 0.141303 GO:0005200 structural constituent of cytoskeleton 2 146 0.6 0.145158 GO:0006366 transcription from Pol II promoter 1 34 0.1 0.145262 GO:0006887 exocytosis 1 34 0.1 0.145262 GO:0008652 amino acid biosynthesis 1 34 0.1 0.145262 GO:0009888 histogenesis 4 444 2 0.14737 GO:0006412 protein biosynthesis 2 151 0.6 0.153125 GO:0007267 cell-cell signaling 16 2670 12.2 0.153425 GO:0005634 nucleus 1 37 0.1 0.157034 GO:0007411 axon guidance 1 37 0.1 0.157034 GO:0019932 second-messenger-mediated signaling 1 39 0.1 0.164792 GO:0030099 myeloid blood cell differentiation 1 39 0.1 0.164792 GO:0042445 hormone metabolism 2 160 0.7 0.167675 GO:0003779 actin binding 1 40 0.1 0.168645 GO:0000165 MAPKKK cascade 1 40 0.1 0.168645 GO:0006445 regulation of translation 2 162 0.7 0.170941 GO:0004713 protein-tyrosine kinase activity 1 41 0.1 0.172481 GO:0006694 steroid biosynthesis 2 165 0.7 0.175861 GO:0005624 membrane fraction 1 42 0.1 0.176299 GO:0006413 translational initiation 31 5837 26.8 0.178314 GO:0008152 metabolism 1 44 0.2 0.183883 GO:0007420 brain development 5 660 3 0.186474 GO:0007242 intracellular signaling cascade 1 46 0.2 0.191398 GO:0006606 protein-nucleus import 1 46 0.2 0.191398 GO:0009795 embryonic morphogenesis 11 3131 14.4 0.194178 u GO:0050875 cellular physiological process 1 47 0.2 0.195131 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1 47 0.2 0.195131 GO:0045211 postsynaptic membrane 2 180 0.8 0.200775 GO:0000267 cell fraction 2 183 0.8 0.205811 GO:0050879 organismal movement 1 51 0.2 0.20989 GO:0005941 unlocalized 1 51 0.2 0.20989 GO:0046873 metal ion transporter activity 6 872 4 0.211233 GO:0009058 biosynthesis 2 187 0.8 0.212547 GO:0016791 phosphoric monoester hydrolase activity 1 53 0.2 0.21717 GO:0009309 amine biosynthesis 5 698 3.2 0.217364 GO:0009887 organogenesis 1 613 2.8 0.22024 u GO:0009057 macromolecule catabolism 1 610 2.8 0.222593 u GO:0030163 protein catabolism 1 55 0.2 0.224383 GO:0004221 ubiquitin thiolesterase activity 12 2048 9.4 0.225611 GO:0050789 regulation of biological process 3 358 1.6 0.227408 GO:0015031 protein transport 1 56 0.2 0.227965 GO:0016563 transcriptional activator activity 1 57 0.2 0.231531 GO:0004843 ubiquitin-specific protease activity 1 57 0.2 0.231531 GO:0009792 embryonic development (sensu Animalia) 1 57 0.2 0.231531 GO:0015992 proton transport 2 200 0.9 0.234581 GO:0005829 cytosol 1 58 0.2 0.235081 GO:0005730 nucleolus 1 58 0.2 0.235081 GO:0006818 hydrogen transport 1 58 0.2 0.235081 GO:0006916 anti-apoptosis 11 1874 8.6 0.238153 GO:0046872 metal ion binding 1 59 0.2 0.238614 GO:0005635 nuclear membrane 1 59 0.2 0.238614 GO:0008081 phosphoric diester hydrolase activity 1 590 2.7 0.238837 u GO:0006508 proteolysis and peptidolysis 5 724 3.3 0.2394 GO:0009059 macromolecule biosynthesis 1 60 0.2 0.242132 GO:0046983 protein dimerization activity 1 62 0.2 0.249119 GO:0007417 central nervous system development 1 63 0.2 0.252588 GO:0006486 protein amino acid glycosylation 1 63 0.2 0.252588 GO:0007409 axonogenesis 1 63 0.2 0.252588 GO:0016568 chromatin modification 1 63 0.2 0.252588 GO:0030036 actin cytoskeleton organization and biogenesis 10 2750 12.6 0.255438 u GO:0008151 cell growth and/or maintenance 1 64 0.2 0.256042 GO:0003743 translation initiation factor activity 1 66 0.3 0.262903 GO:0043066 negative regulation of apoptosis 1 66 0.3 0.262903 GO:0043069 negative regulation of programmed cell death 2 218 1 0.265298 GO:0006886 intracellular protein transport 1 67 0.3 0.26631 GO:0030029 actin filament-based process 3 390 1.7 0.266879 GO:0007155 cell adhesion 1 69 0.3 0.273077 GO:0009101 glycoprotein biosynthesis 1 69 0.3 0.273077 GO:0016790 thiolester hydrolase activity 1 69 0.3 0.273077 GO:0045045 secretory pathway 12 3170 14.5 0.273125 u GO:0007154 cell communication 1 70 0.3 0.276437 GO:0045595 regulation of cell differentiation 1 71 0.3 0.279783 GO:0042625 ATPase activity, coupled to transmembrane movement of ions 2 797 3.6 0.282185 u GO:0009056 catabolism 9 1564 7.1 0.289726 GO:0019222 regulation of metabolism 4 594 2.7 0.291642 GO:0016788 hydrolase activity, acting on ester bonds 10 2672 12.2 0.292562 u GO:0003676 nucleic acid binding 1 75 0.3 0.293012 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 8 1372 6.3 0.294365 GO:0016740 transferase activity 2 238 1 0.299462 GO:0016070 RNA metabolism 1 77 0.3 0.299537 GO:0009100 glycoprotein metabolism 1 81 0.3 0.312409 GO:0000087 M phase of mitotic cell cycle 1 81 0.3 0.312409 GO:0007067 mitosis 1 82 0.3 0.315591 GO:0008202 steroid metabolism 9 1606 7.3 0.317165 GO:0050791 regulation of physiological process 1 83 0.3 0.318758 GO:0007156 homophilic cell adhesion 1 505 2.3 0.319374 u GO:0006259 DNA metabolism 2 250 1.1 0.319867 GO:0016887 ATPase activity 4 625 2.8 0.324086 GO:0005198 structural molecule activity 1 85 0.3 0.325048 GO:0006913 nucleocytoplasmic transport 1 85 0.3 0.325048 GO:0015405 P-P-bond-hydrolysis-driven transporter activity 5 822 3.7 0.327099 GO:0009653 morphogenesis 1 88 0.4 0.334377 GO:0006417 regulation of protein biosynthesis 2 259 1.1 0.335087 GO:0007399 neurogenesis 2 264 1.2 0.343503 GO:0016567 protein ubiquitination 1 91 0.4 0.34358 GO:0004867 serine-type endopeptidase inhibitor activity 1 92 0.4 0.346619 GO:0005083 small GTPase regulatory/interacting protein activity 1 92 0.4 0.346619 GO:0009889 regulation of biosynthesis 6 1656 7.6 0.348109 u GO:0006810 transport 1 93 0.4 0.349644 GO:0006605 protein targeting 2 268 1.2 0.350214 GO:0000151 ubiquitin ligase complex 8 1458 6.7 0.355071 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 96 0.4 0.358639 GO:0008135 translation factor activity, nucleic acid binding 1 97 0.4 0.361609 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1 99 0.4 0.36751 GO:0045182 translation regulator activity 2 280 1.2 0.370208 GO:0005794 Golgi apparatus 1 456 2 0.374901 u GO:0004175 endopeptidase activity 1 102 0.4 0.376261 GO:0006511 ubiquitin-dependent protein catabolism 1 102 0.4 0.376261 GO:0019941 modification-dependent protein catabolism 1 103 0.4 0.379151 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2 286 1.3 0.380119 GO:0005525 GTP binding 1 106 0.4 0.387744 GO:0016477 cell migration 1 107 0.4 0.390582 GO:0030097 hemopoiesis 2 294 1.3 0.393236 GO:0019001 guanyl nucleotide binding 1 108 0.4 0.393407 GO:0006333 chromatin assembly/disassembly 3 491 2.2 0.394361 GO:0007049 cell cycle 2 297 1.3 0.398124 GO:0030001 metal ion transport 1 110 0.5 0.399018 GO:0000280 nuclear division 1 110 0.5 0.399018 GO:0006470 protein amino acid dephosphorylation 1 110 0.5 0.399018 GO:0016758 transferase activity, transferring hexosyl groups 1 433 1.9 0.403368 u GO:0005102 receptor binding 1 113 0.5 0.407339 GO:0016337 cell-cell adhesion 1 114 0.5 0.410088 GO:0015980 energy derivation by oxidation of organic compounds 1 115 0.5 0.412824 GO:0000279 M phase 3 884 4 0.413431 u GO:0050874 organismal physiological process 1 117 0.5 0.418258 GO:0008234 cysteine-type peptidase activity 1 118 0.5 0.420957 GO:0007167 enzyme linked receptor protein signaling pathway 1 120 0.5 0.426317 GO:0006091 energy pathways 3 517 2.3 0.426699 GO:0006950 response to stress 2 319 1.4 0.43341 GO:0050877 neurophysiological process 1 123 0.5 0.434266 GO:0042221 response to chemical substance 2 634 2.9 0.436787 u GO:0005886 plasma membrane 2 632 2.9 0.438962 u GO:0005739 mitochondrion 1 127 0.5 0.444696 GO:0042626 ATPase activity, coupled to transmembrane movement of substances 2 620 2.8 0.452141 u GO:0006811 ion transport 1 130 0.5 0.452395 GO:0015629 actin cytoskeleton 1 130 0.5 0.452395 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1 131 0.6 0.454937 GO:0004866 endopeptidase inhibitor activity 1 131 0.6 0.454937 GO:0015399 primary active transporter activity 1 132 0.6 0.457468 GO:0030414 protease inhibitor activity 4 1058 4.8 0.457645 u GO:0050896 response to stimulus 10 2374 10.9 0.458754 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 7 1393 6.4 0.462442 GO:0006355 regulation of transcription, DNA-dependent 2 345 1.5 0.473694 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1 139 0.6 0.474864 GO:0016023 cytoplasmic vesicle 1 139 0.6 0.474864 GO:0030695 GTPase regulator activity 2 599 2.7 0.475725 u GO:0016491 oxidoreductase activity 2 348 1.6 0.478234 GO:0016817 hydrolase activity, acting on acid anhydrides 2 596 2.7 0.479147 u GO:0003700 transcription factor activity 7 1415 6.5 0.479358 GO:0007275 development 1 141 0.6 0.479733 GO:0000287 magnesium ion binding 1 141 0.6 0.479733 GO:0008610 lipid biosynthesis 7 1417 6.5 0.48089 GO:0006351 transcription, DNA-dependent 1 375 1.7 0.481967 u GO:0003723 RNA binding 4 776 3.5 0.482079 GO:0030528 transcription regulator activity 1 144 0.6 0.486952 GO:0050793 regulation of development 1 149 0.6 0.498767 GO:0006974 response to DNA damage stimulus 5 1221 5.6 0.504013 u GO:0046914 transition metal ion binding 1 152 0.6 0.505726 GO:0000067 DNA replication and chromosome cycle 7 1452 6.6 0.507524 GO:0045449 regulation of transcription 1 157 0.7 0.517114 GO:0009719 response to endogenous stimulus 1 350 1.6 0.518751 u GO:0006629 lipid metabolism 1 158 0.7 0.519361 GO:0006323 DNA packaging 1 158 0.7 0.519361 GO:0006325 establishment and/or maintenance of chromatin architecture 1 158 0.7 0.519361 GO:0006928 cell motility 39 8414 38.7 0.524211 GO:0007582 physiological process 1 346 1.5 0.52479 u GO:0016265 death 42 9173 42.2 0.525976 u GO:0005623 cell 1 343 1.5 0.529346 u GO:0008219 cell death 2 384 1.7 0.530858 GO:0030234 enzyme regulator activity 1 337 1.5 0.538526 u GO:0006118 electron transport 7 1604 7.3 0.53901 u GO:0003677 DNA binding 1 170 0.7 0.545529 GO:0008324 cation transporter activity 3 619 2.8 0.546751 GO:0008283 cell proliferation 1 172 0.7 0.549752 GO:0042981 regulation of apoptosis 3 622 2.8 0.550071 GO:0008233 peptidase activity 2 399 1.8 0.551726 GO:0006812 cation transport 1 174 0.8 0.553936 GO:0043067 regulation of programmed cell death 8 1795 8.2 0.554249 u GO:0016787 hydrolase activity 7 1516 6.9 0.555096 GO:0006350 transcription 1 176 0.8 0.558082 GO:0004857 enzyme inhibitor activity 1 181 0.8 0.568281 GO:0007001 chromosome organization and biogenesis (sensu Eukarya) 3 723 3.3 0.572562 u GO:0005576 extracellular 1 313 1.4 0.576111 u GO:0012501 programmed cell death 1 311 1.4 0.579302 u GO:0005386 carrier activity 1 187 0.8 0.580215 GO:0006997 nuclear organization and biogenesis 1 187 0.8 0.580215 GO:0016757 transferase activity, transferring glycosyl groups 1 309 1.4 0.582502 u GO:0006915 apoptosis 2 496 2.2 0.599384 u GO:0050794 regulation of cellular process 1 294 1.3 0.606764 u GO:0030154 cell differentiation 5 1095 5 0.60922 u GO:0008270 zinc ion binding 1 204 0.9 0.612291 GO:0007264 small GTPase mediated signal transduction 1 204 0.9 0.612291 GO:0009628 response to abiotic stimulus 1 212 0.9 0.626538 GO:0016192 vesicle-mediated transport 1 238 1 0.700538 u GO:0042623 ATPase activity, coupled 1 230 1 0.714191 u GO:0015672 monovalent inorganic cation transport 1 224 1 0.724444 u GO:0015075 ion transporter activity