# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 91 #b referenced loci : 87 #c annotated loci : 77 #d hyper-geometric : n 77 hgN 14129 #e k hgK Exp k p-value term description 2 6 0 0.000433559 GO:0019894 kinesin binding 23 2064 11.2 0.000451063 GO:0005515 protein binding 10 514 2.8 0.000456985 GO:0005856 cytoskeleton 5 2958 16.1 0.000461133 u GO:0004871 signal transducer activity 3 2359 12.8 0.000548868 u GO:0004872 receptor activity 53 7041 38.3 0.00055334 GO:0005488 binding 4 73 0.3 0.000667552 GO:0005875 microtubule associated complex 4 74 0.4 0.000702804 GO:0005516 calmodulin binding 5 138 0.7 0.000929533 GO:0015630 microtubule cytoskeleton 15 1161 6.3 0.00132505 GO:0006464 protein modification 5 157 0.8 0.00165 GO:0012505 endomembrane system 14 1067 5.8 0.00169558 GO:0005524 ATP binding 14 1078 5.8 0.00186745 GO:0030554 adenyl nucleotide binding 43 5553 30.2 0.00234983 GO:0005622 intracellular 11 749 4 0.00235143 GO:0016301 kinase activity 3 49 0.2 0.00239462 GO:0005789 endoplasmic reticulum membrane 16 1366 7.4 0.00248644 GO:0017076 purine nucleotide binding 3 50 0.2 0.00253756 GO:0042175 nuclear envelope-endoplasmic reticulum network 16 1374 7.4 0.00263813 GO:0000166 nucleotide binding 7 345 1.8 0.00270766 GO:0004674 protein serine/threonine kinase activity 9 3552 19.3 0.00280073 u GO:0016021 integral to membrane 25 2707 14.7 0.00374624 GO:0005737 cytoplasm 3 1922 10.4 0.00470372 u GO:0007166 cell surface receptor linked signal transduction 1 1 0 0.00544978 GO:0004438 phosphatidylinositol-3-phosphatase activity 1 1 0 0.00544978 GO:0004691 cAMP-dependent protein kinase activity 1 1 0 0.00544978 GO:0005955 calcineurin complex 1 1 0 0.00544978 GO:0007274 neuromuscular synaptic transmission 1 1 0 0.00544978 GO:0008089 anterograde axon cargo transport 1 1 0 0.00544978 GO:0016939 kinesin II complex 1 1 0 0.00544978 GO:0019987 negative regulation of anti-apoptosis 1 1 0 0.00544978 GO:0030325 adrenal gland development 8 496 2.7 0.00549205 GO:0004672 protein kinase activity 2 1597 8.7 0.00559587 u GO:0007186 G-protein coupled receptor protein signaling pathway 2 21 0.1 0.00575676 GO:0043087 regulation of GTPase activity 22 2384 12.9 0.00713136 GO:0019538 protein metabolism 9 669 3.6 0.0103202 GO:0006793 phosphorus metabolism 9 669 3.6 0.0103202 GO:0006796 phosphate metabolism 3 84 0.4 0.0108106 GO:0007017 microtubule-based process 1 2 0 0.0108703 GO:0000209 protein polyubiquitination 1 2 0 0.0108703 GO:0001672 regulation of chromatin assembly/disassembly 1 2 0 0.0108703 GO:0004827 proline-tRNA ligase activity 1 2 0 0.0108703 GO:0006433 prolyl-tRNA aminoacylation 1 2 0 0.0108703 GO:0008250 oligosaccharyl transferase complex 1 2 0 0.0108703 GO:0018196 peptidyl-asparagine modification 1 2 0 0.0108703 GO:0018279 N-linked glycosylation via asparagine 1 2 0 0.0108703 GO:0030517 negative regulation of axon extension 1 2 0 0.0108703 GO:0045646 regulation of erythrocyte differentiation 1 2 0 0.0108703 GO:0045648 positive regulation of erythrocyte differentiation 7 460 2.5 0.0125498 GO:0016874 ligase activity 8 586 3.1 0.0142349 GO:0016773 phosphotransferase activity, alcohol group as acceptor 6 368 2 0.0150696 GO:0006512 ubiquitin cycle 1 3 0 0.0162616 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 1 3 0 0.0162616 GO:0004690 cyclic nucleotide-dependent protein kinase activity 1 3 0 0.0162616 GO:0004818 glutamate-tRNA ligase activity 1 3 0 0.0162616 GO:0004828 serine-tRNA ligase activity 1 3 0 0.0162616 GO:0005869 dynactin complex 1 3 0 0.0162616 GO:0006424 glutamyl-tRNA aminoacylation 1 3 0 0.0162616 GO:0006434 seryl-tRNA aminoacylation 2 38 0.2 0.0181559 GO:0007018 microtubule-based movement 2 38 0.2 0.0181559 GO:0030705 cytoskeleton-dependent intracellular transport 3 102 0.5 0.0181732 GO:0045202 synapse 2 39 0.2 0.0190706 GO:0006418 tRNA aminoacylation for protein translation 2 39 0.2 0.0190706 GO:0043038 amino acid activation 2 39 0.2 0.0190706 GO:0043039 tRNA aminoacylation 7 509 2.7 0.020745 GO:0006468 protein amino acid phosphorylation 2 41 0.2 0.0209568 GO:0004812 tRNA ligase activity 2 41 0.2 0.0209568 GO:0008452 RNA ligase activity 2 41 0.2 0.0209568 GO:0016875 ligase activity, forming carbon-oxygen bonds 2 41 0.2 0.0209568 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds 1 4 0 0.0216239 GO:0001515 opioid peptide activity 1 4 0 0.0216239 GO:0007435 salivary gland morphogenesis 1 4 0 0.0216239 GO:0008088 axon cargo transport 1 4 0 0.0216239 GO:0045639 positive regulation of myeloid blood cell differentiation 1 4 0 0.0216239 GO:0045767 regulation of anti-apoptosis 2 42 0.2 0.021928 GO:0006400 tRNA modification 4 204 1.1 0.0252068 GO:0007010 cytoskeleton organization and biogenesis 22 2670 14.5 0.0253454 GO:0005634 nucleus 2 46 0.2 0.0259943 GO:0006606 protein-nucleus import 5 307 1.6 0.0260017 GO:0004842 ubiquitin-protein ligase activity 1 5 0 0.0269573 GO:0000145 exocyst 1 5 0 0.0269573 GO:0004576 oligosaccharyl transferase activity 1 5 0 0.0269573 GO:0008717 D-alanyl-D-alanine endopeptidase activity 1 5 0 0.0269573 GO:0030516 regulation of axon extension 1 5 0 0.0269573 GO:0030865 cortical cytoskeleton organization and biogenesis 1 5 0 0.0269573 GO:0030866 cortical actin cytoskeleton organization and biogenesis 2 47 0.2 0.0270553 GO:0016886 ligase activity, forming phosphoric ester bonds 3 119 0.6 0.027149 GO:0007243 protein kinase cascade 3 119 0.6 0.027149 GO:0009790 embryonic development 2 49 0.2 0.0292287 GO:0009451 RNA modification 2 50 0.2 0.0303408 GO:0050790 regulation of enzyme activity 33 4537 24.7 0.0305781 GO:0003824 catalytic activity 5 321 1.7 0.0307078 GO:0046907 intracellular transport 3 127 0.6 0.0320563 GO:0043037 translation 1 6 0 0.0322621 GO:0001658 ureteric bud branching 1 6 0 0.0322621 GO:0001704 formation of primary germ layer 1 6 0 0.0322621 GO:0001707 mesoderm formation 1 6 0 0.0322621 GO:0003756 protein disulfide isomerase activity 1 6 0 0.0322621 GO:0007270 nerve-nerve synaptic transmission 1 6 0 0.0322621 GO:0007431 salivary gland development 1 6 0 0.0322621 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1 6 0 0.0322621 GO:0042577 lipid phosphatase activity 1 6 0 0.0322621 GO:0048332 mesoderm morphogenesis 7 559 3 0.0323887 GO:0016310 phosphorylation 5 326 1.7 0.0325107 GO:0016881 acid-D-amino acid ligase activity 4 222 1.2 0.0329601 GO:0008092 cytoskeletal protein binding 3 131 0.7 0.0346728 GO:0003774 motor activity 3 132 0.7 0.0353438 GO:0006520 amino acid metabolism 2 55 0.2 0.0361471 GO:0004221 ubiquitin thiolesterase activity 1 7 0 0.0375383 GO:0005388 calcium-transporting ATPase activity 1 7 0 0.0375383 GO:0006564 L-serine biosynthesis 1 7 0 0.0375383 GO:0015085 calcium ion transporter activity 2 57 0.3 0.0385804 GO:0004843 ubiquitin-specific protease activity 2 59 0.3 0.0410746 GO:0005635 nuclear membrane 1 8 0 0.0427861 GO:0005871 kinesin complex 1 8 0 0.0427861 GO:0007595 lactation 1 8 0 0.0427861 GO:0015035 protein disulfide oxidoreductase activity 1 8 0 0.0427861 GO:0030218 erythrocyte differentiation 1 8 0 0.0427861 GO:0030659 cytoplasmic vesicle membrane 4 244 1.3 0.0441441 GO:0006996 organelle organization and biogenesis 2 62 0.3 0.0449266 GO:0004840 ubiquitin conjugating enzyme activity 2 62 0.3 0.0449266 GO:0008639 small protein conjugating enzyme activity 5 358 1.9 0.0456165 GO:0015031 protein transport 5 360 1.9 0.046527 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1 9 0 0.0480056 GO:0017124 SH3 domain binding 2 65 0.3 0.0489068 GO:0006399 tRNA metabolism 1 10 0 0.0531971 GO:0001763 branching morphogenesis 1 10 0 0.0531971 GO:0006563 L-serine metabolism 1 10 0 0.0531971 GO:0009070 serine family amino acid biosynthesis 2 69 0.3 0.0544046 GO:0016790 thiolester hydrolase activity 2 70 0.3 0.0558119 GO:0006816 calcium ion transport 18 4555 24.8 0.0581613 u GO:0016020 membrane 8 771 4.2 0.0581855 GO:0016772 transferase activity, transferring phosphorus-containing groups 1 11 0 0.0583606 GO:0001657 ureteric bud development 1 11 0 0.0583606 GO:0042472 inner ear morphogenesis 1 11 0 0.0583606 GO:0051052 regulation of DNA metabolism 3 167 0.9 0.0629498 GO:0006519 amino acid and derivative metabolism 1 12 0 0.0634964 GO:0006487 N-linked glycosylation 1 12 0 0.0634964 GO:0007189 G-protein signaling, adenylate cyclase activating pathway 1 12 0 0.0634964 GO:0042471 ear morphogenesis 7 660 3.5 0.0677391 GO:0007242 intracellular signaling cascade 1 13 0 0.0686044 GO:0005938 cell cortex 1 13 0 0.0686044 GO:0006446 regulation of translational initiation 1 13 0 0.0686044 GO:0007498 mesoderm development 1 13 0 0.0686044 GO:0007548 sex differentiation 1 13 0 0.0686044 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 1 13 0 0.0686044 GO:0016998 cell wall catabolism 1 13 0 0.0686044 GO:0042493 response to drug 4 286 1.5 0.070727 GO:0007028 cytoplasm organization and biogenesis 1 14 0 0.073685 GO:0006700 C21-steroid hormone biosynthesis 1 14 0 0.073685 GO:0009069 serine family amino acid metabolism 1 14 0 0.073685 GO:0012506 vesicle membrane 3 181 0.9 0.0761209 GO:0009308 amine metabolism 2 85 0.4 0.0783583 GO:0006913 nucleocytoplasmic transport 1 15 0 0.0787382 GO:0000059 protein-nucleus import, docking 1 15 0 0.0787382 GO:0004722 protein serine/threonine phosphatase activity 1 15 0 0.0787382 GO:0008207 C21-steroid hormone metabolism 1 15 0 0.0787382 GO:0008286 insulin receptor signaling pathway 1 15 0 0.0787382 GO:0045637 regulation of myeloid blood cell differentiation 1 16 0 0.0837643 GO:0007059 chromosome segregation 1 16 0 0.0837643 GO:0030176 integral to endoplasmic reticulum membrane 16 2048 11.1 0.083944 GO:0050789 regulation of biological process 1 17 0 0.0887632 GO:0016323 basolateral plasma membrane 2 92 0.5 0.089705 GO:0005083 small GTPase regulatory/interacting protein activity 2 93 0.5 0.091364 GO:0006605 protein targeting 1 18 0 0.0937352 GO:0001656 metanephros development 1 18 0 0.0937352 GO:0001822 kidney development 1 18 0 0.0937352 GO:0004437 inositol/phosphatidylinositol phosphatase activity 1 18 0 0.0937352 GO:0042446 hormone biosynthesis 38 5837 31.8 0.0939782 GO:0008152 metabolism 3 200 1 0.095762 GO:0005829 cytosol 1 19 0.1 0.0986805 GO:0001655 urogenital system development 1 19 0.1 0.0986805 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 1 19 0.1 0.0986805 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 1 19 0.1 0.0986805 GO:0030286 dynein complex 4 327 1.7 0.10303 GO:0005783 endoplasmic reticulum 1 20 0.1 0.103599 GO:0007369 gastrulation 1 20 0.1 0.103599 GO:0045597 positive regulation of cell differentiation 2 102 0.5 0.106686 GO:0006511 ubiquitin-dependent protein catabolism 2 102 0.5 0.106686 GO:0019941 modification-dependent protein catabolism 1 21 0.1 0.108491 GO:0000082 G1/S transition of mitotic cell cycle 1 21 0.1 0.108491 GO:0008287 protein serine/threonine phosphatase complex 1 22 0.1 0.113357 GO:0046982 protein heterodimerization activity 3 218 1.1 0.116077 GO:0006886 intracellular protein transport 3 1147 6.2 0.118925 u GO:0005215 transporter activity 2 110 0.5 0.120841 GO:0015674 di-, tri-valent inorganic cation transport 1 24 0.1 0.12301 GO:0003777 microtubule motor activity 1 24 0.1 0.12301 GO:0006112 energy reserve metabolism 1 24 0.1 0.12301 GO:0015082 di-, tri-valent inorganic cation transporter activity 1 24 0.1 0.12301 GO:0019933 cAMP-mediated signaling 1 24 0.1 0.12301 GO:0030100 regulation of endocytosis 2 112 0.6 0.12445 GO:0006357 regulation of transcription from Pol II promoter 2 112 0.6 0.12445 GO:0016311 dephosphorylation 1 25 0.1 0.127798 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1 25 0.1 0.127798 GO:0008017 microtubule binding 5 491 2.6 0.129491 GO:0007049 cell cycle 2 117 0.6 0.133584 GO:0008234 cysteine-type peptidase activity 2 879 4.7 0.134331 u GO:0009605 response to external stimulus 2 118 0.6 0.135429 GO:0000278 mitotic cell cycle 5 500 2.7 0.136779 GO:0005509 calcium ion binding 1 27 0.1 0.137295 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1 27 0.1 0.137295 GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity 1 28 0.1 0.142006 GO:0005643 nuclear pore 1 28 0.1 0.142006 GO:0019935 cyclic-nucleotide-mediated signaling 1 28 0.1 0.142006 GO:0046930 pore complex 2 122 0.6 0.142867 GO:0007268 synaptic transmission 3 243 1.3 0.146695 GO:0042578 phosphoric ester hydrolase activity 1 30 0.1 0.151351 GO:0015631 tubulin binding 2 128 0.6 0.154181 GO:0004721 phosphoprotein phosphatase activity 2 128 0.6 0.154181 GO:0019226 transmission of nerve impulse 2 128 0.6 0.154181 GO:0050905 neuromuscular physiological process 1 31 0.1 0.155986 GO:0015036 disulfide oxidoreductase activity 1 31 0.1 0.155986 GO:0050876 reproductive physiological process 1 32 0.1 0.160596 GO:0018193 peptidyl-amino acid modification 1 32 0.1 0.160596 GO:0019904 protein domain specific binding 11 2728 14.8 0.164964 u GO:0007165 signal transduction 1 33 0.1 0.165181 GO:0003702 RNA polymerase II transcription factor activity 1 33 0.1 0.165181 GO:0005200 structural constituent of cytoskeleton 1 33 0.1 0.165181 GO:0016860 intramolecular oxidoreductase activity 1 34 0.1 0.169741 GO:0006887 exocytosis 1 34 0.1 0.169741 GO:0008652 amino acid biosynthesis 1 34 0.1 0.169741 GO:0009888 histogenesis 3 262 1.4 0.171549 GO:0019752 carboxylic acid metabolism 3 264 1.4 0.174234 GO:0016567 protein ubiquitination 2 139 0.7 0.175348 GO:0030695 GTPase regulator activity 3 265 1.4 0.175581 GO:0006082 organic acid metabolism 3 268 1.4 0.17964 GO:0000151 ubiquitin ligase complex 3 270 1.4 0.182361 GO:0005578 extracellular matrix 1 37 0.2 0.183274 GO:0007411 axon guidance 1 37 0.2 0.183274 GO:0019932 second-messenger-mediated signaling 2 146 0.7 0.189053 GO:0006366 transcription from Pol II promoter 1 39 0.2 0.192176 GO:0030099 myeloid blood cell differentiation 1 39 0.2 0.192176 GO:0042445 hormone metabolism 1 40 0.2 0.19659 GO:0000165 MAPKKK cascade 1 40 0.2 0.19659 GO:0006445 regulation of translation 2 151 0.8 0.198932 GO:0007267 cell-cell signaling 2 152 0.8 0.200916 GO:0000067 DNA replication and chromosome cycle 1 41 0.2 0.200981 GO:0006694 steroid biosynthesis 1 42 0.2 0.205348 GO:0006413 translational initiation 5 582 3.1 0.210812 GO:0016043 cell organization and biogenesis 1 44 0.2 0.214012 GO:0007420 brain development 13 1874 10.2 0.215434 GO:0046872 metal ion binding 2 160 0.8 0.216865 GO:0003779 actin binding 2 162 0.8 0.220872 GO:0004713 protein-tyrosine kinase activity 1 46 0.2 0.222583 GO:0009795 embryonic morphogenesis 5 594 3.2 0.22263 GO:0016788 hydrolase activity, acting on ester bonds 4 444 2.4 0.223067 GO:0006412 protein biosynthesis 28 5831 31.7 0.224349 u GO:0009987 cellular process 1 47 0.2 0.226833 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1 47 0.2 0.226833 GO:0045211 postsynaptic membrane 2 165 0.8 0.226894 GO:0005624 membrane fraction 11 1564 8.5 0.228761 GO:0019222 regulation of metabolism 1 49 0.2 0.235266 GO:0051049 regulation of transport 1 51 0.2 0.243607 GO:0005941 unlocalized 1 51 0.2 0.243607 GO:0046873 metal ion transporter activity 1 52 0.2 0.247745 GO:0045786 negative regulation of cell cycle 5 619 3.3 0.247885 GO:0008283 cell proliferation 1 53 0.2 0.251859 GO:0009309 amine biosynthesis 3 319 1.7 0.251948 GO:0050877 neurophysiological process 5 625 3.4 0.254061 GO:0005198 structural molecule activity 11 1606 8.7 0.255598 GO:0050791 regulation of physiological process 2 180 0.9 0.257154 GO:0000267 cell fraction 2 183 0.9 0.263223 GO:0050879 organismal movement 1 56 0.3 0.264071 GO:0016563 transcriptional activator activity 1 57 0.3 0.268097 GO:0009792 embryonic development (sensu Animalia) 1 57 0.3 0.268097 GO:0015992 proton transport 10 1458 7.9 0.268878 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 49 8414 45.8 0.27062 GO:0007582 physiological process 2 187 1 0.271317 GO:0016791 phosphoric monoester hydrolase activity 1 58 0.3 0.272102 GO:0005730 nucleolus 1 58 0.3 0.272102 GO:0006818 hydrogen transport 1 58 0.3 0.272102 GO:0006916 anti-apoptosis 1 59 0.3 0.276086 GO:0008081 phosphoric diester hydrolase activity 1 60 0.3 0.280047 GO:0046983 protein dimerization activity 12 2672 14.5 0.28037 u GO:0003676 nucleic acid binding 4 496 2.7 0.285179 GO:0050794 regulation of cellular process 1 62 0.3 0.287907 GO:0007417 central nervous system development 1 63 0.3 0.291804 GO:0006486 protein amino acid glycosylation 1 63 0.3 0.291804 GO:0007409 axonogenesis 1 63 0.3 0.291804 GO:0016568 chromatin modification 1 63 0.3 0.291804 GO:0030036 actin cytoskeleton organization and biogenesis 1 64 0.3 0.295681 GO:0003743 translation initiation factor activity 1 66 0.3 0.303372 GO:0043066 negative regulation of apoptosis 1 66 0.3 0.303372 GO:0043069 negative regulation of programmed cell death 1 67 0.3 0.307186 GO:0030029 actin filament-based process 4 517 2.8 0.311038 GO:0006950 response to stress 1 433 2.3 0.311778 u GO:0005102 receptor binding 1 69 0.3 0.314753 GO:0009101 glycoprotein biosynthesis 1 69 0.3 0.314753 GO:0045045 secretory pathway 1 70 0.3 0.318506 GO:0045595 regulation of cell differentiation 15 3170 17.2 0.320373 u GO:0007154 cell communication 2 212 1.1 0.321743 GO:0016192 vesicle-mediated transport 2 634 3.4 0.322184 u GO:0005886 plasma membrane 1 71 0.3 0.322239 GO:0042625 ATPase activity, coupled to transmembrane movement of ions 2 632 3.4 0.324284 u GO:0005739 mitochondrion 9 1372 7.4 0.330764 GO:0016740 transferase activity 5 698 3.8 0.331768 GO:0009887 organogenesis 1 75 0.4 0.336968 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 2 620 3.3 0.337091 u GO:0006811 ion transport 6 872 4.7 0.339039 GO:0009058 biosynthesis 1 77 0.4 0.344213 GO:0009100 glycoprotein metabolism 9 1393 7.5 0.347305 GO:0006355 regulation of transcription, DNA-dependent 3 384 2 0.348781 GO:0030234 enzyme regulator activity 1 79 0.4 0.351381 GO:0009966 regulation of signal transduction 3 390 2.1 0.357759 GO:0007155 cell adhesion 1 81 0.4 0.358471 GO:0000087 M phase of mitotic cell cycle 1 81 0.4 0.358471 GO:0007067 mitosis 5 724 3.9 0.360158 GO:0009059 macromolecule biosynthesis 1 82 0.4 0.361988 GO:0008202 steroid metabolism 1 83 0.4 0.365485 GO:0007156 homophilic cell adhesion 9 1417 7.7 0.366381 GO:0006351 transcription, DNA-dependent 2 590 3.2 0.370643 u GO:0006508 proteolysis and peptidolysis 1 85 0.4 0.372423 GO:0015405 P-P-bond-hydrolysis-driven transporter activity 2 238 1.2 0.373296 GO:0016070 RNA metabolism 1 88 0.4 0.38269 GO:0006417 regulation of protein biosynthesis 7 1095 5.9 0.388126 GO:0008270 zinc ion binding 1 375 2 0.389853 u GO:0003723 RNA binding 1 91 0.4 0.392791 GO:0004867 serine-type endopeptidase inhibitor activity 9 1452 7.9 0.394432 GO:0045449 regulation of transcription 1 92 0.5 0.396121 GO:0009889 regulation of biosynthesis 2 250 1.3 0.396592 GO:0016887 ATPase activity 1 96 0.5 0.409264 GO:0004197 cysteine-type endopeptidase activity 1 96 0.5 0.409264 GO:0008135 translation factor activity, nucleic acid binding 1 97 0.5 0.412506 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2 259 1.4 0.41381 GO:0007399 neurogenesis 5 776 4.2 0.417133 GO:0030528 transcription regulator activity 1 99 0.5 0.418936 GO:0045182 translation regulator activity 1 101 0.5 0.425297 GO:0008565 protein transporter activity 1 350 1.9 0.427728 u GO:0006629 lipid metabolism 1 103 0.5 0.431589 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1 346 1.8 0.434024 u GO:0016265 death 1 343 1.8 0.438789 u GO:0008219 cell death 3 723 3.9 0.439841 u GO:0005576 extracellular 1 106 0.5 0.4409 GO:0016477 cell migration 4 622 3.3 0.441524 GO:0008233 peptidase activity 1 107 0.5 0.44397 GO:0030097 hemopoiesis 9 1516 8.2 0.445997 GO:0006350 transcription 1 108 0.5 0.447023 GO:0006333 chromatin assembly/disassembly 16 3131 17 0.448345 u GO:0050875 cellular physiological process 49 9173 49.9 0.448641 u GO:0005623 cell 2 280 1.5 0.453028 GO:0005794 Golgi apparatus 1 110 0.5 0.45308 GO:0000280 nuclear division 1 110 0.5 0.45308 GO:0006470 protein amino acid dephosphorylation 1 110 0.5 0.45308 GO:0016758 transferase activity, transferring hexosyl groups 12 2374 12.9 0.460058 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 113 0.6 0.462043 GO:0016337 cell-cell adhesion 2 286 1.5 0.463966 GO:0005525 GTP binding 1 114 0.6 0.464999 GO:0015980 energy derivation by oxidation of organic compounds 5 822 4.4 0.466991 GO:0009653 morphogenesis 4 884 4.8 0.467867 u GO:0050874 organismal physiological process 1 115 0.6 0.467938 GO:0000279 M phase 1 117 0.6 0.473769 GO:0006897 endocytosis 1 118 0.6 0.476661 GO:0007167 enzyme linked receptor protein signaling pathway 2 505 2.7 0.477148 u GO:0006259 DNA metabolism 2 294 1.6 0.478353 GO:0019001 guanyl nucleotide binding 2 294 1.6 0.478353 GO:0030154 cell differentiation 1 120 0.6 0.482397 GO:0006091 energy pathways 2 297 1.6 0.483689 GO:0030001 metal ion transport 1 121 0.6 0.485242 GO:0016853 isomerase activity 1 313 1.7 0.488416 u GO:0012501 programmed cell death 1 123 0.6 0.490886 GO:0005489 electron transporter activity 1 123 0.6 0.490886 GO:0042221 response to chemical substance 1 311 1.6 0.49185 u GO:0005386 carrier activity 1 124 0.6 0.493685 GO:0019028 viral capsid 1 309 1.6 0.495299 u GO:0006915 apoptosis 1 125 0.6 0.496469 GO:0019012 virion 1 127 0.6 0.501991 GO:0042626 ATPase activity, coupled to transmembrane movement of substances 7 1221 6.6 0.502447 GO:0046914 transition metal ion binding 1 129 0.7 0.507453 GO:0006260 DNA replication 1 130 0.7 0.510162 GO:0015629 actin cytoskeleton 1 130 0.7 0.510162 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 8 1415 7.7 0.51176 GO:0007275 development 1 131 0.7 0.512857 GO:0004866 endopeptidase inhibitor activity 1 131 0.7 0.512857 GO:0015399 primary active transporter activity 1 132 0.7 0.515536 GO:0030414 protease inhibitor activity 9 1604 8.7 0.51613 GO:0003677 DNA binding 6 1058 5.7 0.521317 GO:0050896 response to stimulus 10 1795 9.7 0.521623 GO:0016787 hydrolase activity 1 139 0.7 0.533891 GO:0016023 cytoplasmic vesicle 1 141 0.7 0.539008 GO:0000287 magnesium ion binding 1 141 0.7 0.539008 GO:0008610 lipid biosynthesis 15 2750 14.9 0.544389 GO:0008151 cell growth and/or maintenance 2 456 2.4 0.545274 u GO:0004175 endopeptidase activity 1 144 0.7 0.54658 GO:0050793 regulation of development 2 337 1.8 0.551572 GO:0006118 electron transport 1 149 0.8 0.558927 GO:0006974 response to DNA damage stimulus 4 797 4.3 0.559994 u GO:0009056 catabolism 2 345 1.8 0.564392 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2 348 1.8 0.569132 GO:0016817 hydrolase activity, acting on acid anhydrides 3 613 3.3 0.56953 u GO:0009057 macromolecule catabolism 3 610 3.3 0.573226 u GO:0030163 protein catabolism 1 157 0.8 0.577996 GO:0009719 response to endogenous stimulus 1 158 0.8 0.580322 GO:0006323 DNA packaging 1 158 0.8 0.580322 GO:0006325 establishment and/or maintenance of chromatin architecture 1 158 0.8 0.580322 GO:0006928 cell motility 9 1656 9 0.584131 u GO:0006810 transport 3 599 3.2 0.586823 u GO:0016491 oxidoreductase activity 3 596 3.2 0.590541 u GO:0003700 transcription factor activity 1 170 0.9 0.607262 GO:0008324 cation transporter activity 1 172 0.9 0.611583 GO:0042981 regulation of apoptosis 1 174 0.9 0.615857 GO:0043067 regulation of programmed cell death 1 176 0.9 0.620085 GO:0004857 enzyme inhibitor activity 1 238 1.2 0.626704 u GO:0042623 ATPase activity, coupled 2 399 2.1 0.628801 u GO:0006812 cation transport 1 181 0.9 0.630454 GO:0007001 chromosome organization and biogenesis (sensu Eukarya) 1 230 1.2 0.642426 u GO:0015672 monovalent inorganic cation transport 1 224 1.2 0.654306 u GO:0015075 ion transporter activity 1 211 1.1 0.680263 u GO:0009581 detection of external stimulus 1 204 1.1 0.694337 u GO:0007264 small GTPase mediated signal transduction 1 204 1.1 0.694337 u GO:0009628 response to abiotic stimulus 1 198 1 0.70644 u GO:0000074 regulation of cell cycle 1 197 1 0.70846 u GO:0007600 sensory perception 1 187 1 0.728683 u GO:0006997 nuclear organization and biogenesis 1 187 1 0.728683 u GO:0016757 transferase activity, transferring glycosyl groups