# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 32 #b referenced loci : 31 #c annotated loci : 23 #d hyper-geometric : n 23 hgN 14129 #e k hgK Exp k p-value term description 4 212 0.3 0.000348755 GO:0016192 vesicle-mediated transport 2 24 0 0.000684544 GO:0030100 regulation of endocytosis 3 117 0.1 0.000868487 GO:0006897 endocytosis 4 350 0.5 0.00225737 GO:0006629 lipid metabolism 2 49 0 0.00284551 GO:0051049 regulation of transport 1 2 0 0.00325318 GO:0000209 protein polyubiquitination 1 2 0 0.00325318 GO:0001786 phosphatidylserine binding 1 2 0 0.00325318 GO:0008429 phosphatidylethanolamine binding 8 1656 2.6 0.00338876 GO:0006810 transport 1 3 0 0.00487597 GO:0042147 retrograde transport, endosome to Golgi 1 3 0 0.00487597 GO:0045806 negative regulation of endocytosis 1 4 0 0.00649624 GO:0003997 acyl-CoA oxidase activity 1 4 0 0.00649624 GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors 1 5 0 0.00811398 GO:0004287 prolyl oligopeptidase activity 1 5 0 0.00811398 GO:0006910 phagocytosis, recognition 1 5 0 0.00811398 GO:0017137 Rab interactor activity 1 6 0 0.0097292 GO:0051051 negative regulation of transport 1 7 0 0.0113419 GO:0045444 adipocyte differentiation 1 8 0 0.0129521 GO:0006635 fatty acid beta-oxidation 1 8 0 0.0129521 GO:0006911 phagocytosis, engulfment 1 8 0 0.0129521 GO:0019905 syntaxin binding 8 2064 3.3 0.0129681 GO:0005515 protein binding 1 9 0 0.0145598 GO:0000086 G2/M transition of mitotic cell cycle 1 9 0 0.0145598 GO:0009618 response to pathogenic bacteria 1 9 0 0.0145598 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2 118 0.1 0.0156047 GO:0000278 mitotic cell cycle 1 10 0 0.016165 GO:0005178 integrin binding 1 10 0 0.016165 GO:0016358 dendrite morphogenesis 1 11 0 0.0177676 GO:0000149 SNARE binding 1 11 0 0.0177676 GO:0005802 Golgi trans face 1 12 0 0.0193678 GO:0050764 regulation of phagocytosis 1 12 0 0.0193678 GO:0050766 positive regulation of phagocytosis 1 13 0 0.0209655 GO:0016197 endosome transport 1 13 0 0.0209655 GO:0019395 fatty acid oxidation 2 141 0.2 0.0218134 GO:0000287 magnesium ion binding 1 14 0 0.0225607 GO:0045807 positive regulation of endocytosis 1 14 0 0.0225607 GO:0046777 autophosphorylation 6 1415 2.3 0.0226578 GO:0007275 development 9 2750 4.4 0.0230656 GO:0008151 cell growth and/or maintenance 1 15 0 0.0241534 GO:0004722 protein serine/threonine phosphatase activity 1 16 0 0.0257436 GO:0006289 nucleotide-excision repair 1 17 0 0.0273314 GO:0007032 endosome organization and biogenesis 1 18 0 0.0289167 GO:0051050 positive regulation of transport 1 20 0 0.0320798 GO:0006909 phagocytosis 1 21 0 0.0336577 GO:0000082 G1/S transition of mitotic cell cycle 1 21 0 0.0336577 GO:0008287 protein serine/threonine phosphatase complex 5 1161 1.8 0.0359419 GO:0006464 protein modification 1 23 0 0.036806 GO:0005905 coated pit 1 24 0 0.0383765 GO:0007338 fertilization (sensu Animalia) 1 24 0 0.0383765 GO:0009566 fertilization 1 25 0 0.0399446 GO:0007249 I-kappaB kinase/NF-kappaB cascade 1 25 0 0.0399446 GO:0009617 response to bacteria 2 203 0.3 0.042645 GO:0000003 reproduction 2 203 0.3 0.042645 GO:0019953 sexual reproduction 1 28 0 0.0446341 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 16 7041 11.4 0.0449049 GO:0005488 binding 1 2728 4.4 0.0466779 u GO:0007165 signal transduction 2 3552 5.7 0.0476223 u GO:0016021 integral to membrane 18 8414 13.6 0.0492876 GO:0007582 physiological process 9 3131 5 0.0498134 GO:0050875 cellular physiological process 2 222 0.3 0.0500859 GO:0008092 cytoskeletal protein binding 1 2672 4.3 0.0511317 u GO:0003676 nucleic acid binding 1 34 0 0.0539474 GO:0008203 cholesterol metabolism 8 2707 4.4 0.0575034 GO:0005737 cytoplasm 1 37 0 0.0585714 GO:0005319 lipid transporter activity 1 38 0 0.060108 GO:0016125 sterol metabolism 1 39 0 0.0616421 GO:0005543 phospholipid binding 1 42 0 0.0662301 GO:0030145 manganese ion binding 2 264 0.4 0.0680423 GO:0016567 protein ubiquitination 2 268 0.4 0.0698519 GO:0000151 ubiquitin ligase complex 6 1874 3 0.0742621 GO:0046872 metal ion binding 1 48 0 0.075342 GO:0009897 external side of plasma membrane 1 48 0 0.075342 GO:0019897 extrinsic to plasma membrane 2 280 0.4 0.0753766 GO:0005794 Golgi apparatus 1 49 0 0.0768523 GO:0019898 extrinsic to membrane 1 51 0 0.0798659 GO:0005615 extracellular space 1 51 0 0.0798659 GO:0005941 unlocalized 1 51 0 0.0798659 GO:0016042 lipid catabolism 2 294 0.4 0.0819964 GO:0030154 cell differentiation 1 53 0 0.0828701 GO:0006869 lipid transport 2 3170 5.1 0.0833665 u GO:0007154 cell communication 1 54 0 0.0843687 GO:0000375 RNA splicing, via transesterification reactions 1 54 0 0.0843687 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1 54 0 0.0843687 GO:0000398 nuclear mRNA splicing, via spliceosome 1 54 0 0.0843687 GO:0005777 peroxisome 1 54 0 0.0843687 GO:0042579 microbody 11 4537 7.3 0.0847 GO:0003824 catalytic activity 2 307 0.4 0.0883025 GO:0004842 ubiquitin-protein ligase activity 4 4555 7.4 0.0923023 u GO:0016020 membrane 3 669 1 0.0927237 GO:0006793 phosphorus metabolism 3 669 1 0.0927237 GO:0006796 phosphate metabolism 2 326 0.5 0.0977767 GO:0016881 acid-D-amino acid ligase activity 1 65 0.1 0.100699 GO:0015293 symporter activity 2 337 0.5 0.103393 GO:0006118 electron transport 1 67 0.1 0.103638 GO:0008380 RNA splicing 2 345 0.5 0.107534 GO:0004674 protein serine/threonine kinase activity 1 70 0.1 0.10803 GO:0006816 calcium ion transport 1 74 0.1 0.113853 GO:0005516 calmodulin binding 2 358 0.5 0.114361 GO:0015031 protein transport 2 360 0.5 0.115422 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2 368 0.5 0.11969 GO:0006512 ubiquitin cycle 3 749 1.2 0.119765 GO:0016301 kinase activity 1 79 0.1 0.121081 GO:0007517 muscle development 1 82 0.1 0.125391 GO:0008202 steroid metabolism 1 82 0.1 0.125391 GO:0009986 cell surface 1 92 0.1 0.139611 GO:0005083 small GTPase regulatory/interacting protein activity 1 92 0.1 0.139611 GO:0006631 fatty acid metabolism 1 95 0.1 0.143833 GO:0007283 spermatogenesis 1 95 0.1 0.143833 GO:0048232 male gamete generation 1 97 0.1 0.146637 GO:0006397 mRNA processing 12 5553 9 0.146774 GO:0005622 intracellular 1 102 0.1 0.153609 GO:0019866 inner membrane 5 1795 2.9 0.159031 GO:0016787 hydrolase activity 1 106 0.1 0.159147 GO:0016071 mRNA metabolism 2 2670 4.3 0.162296 u GO:0005634 nucleus 1 110 0.1 0.164651 GO:0006470 protein amino acid dephosphorylation 1 110 0.1 0.164651 GO:0015674 di-, tri-valent inorganic cation transport 1 112 0.1 0.16739 GO:0016311 dephosphorylation 2 460 0.7 0.171328 GO:0016874 ligase activity 1 119 0.1 0.176908 GO:0007243 protein kinase cascade 6 2384 3.8 0.179595 GO:0019538 protein metabolism 1 125 0.2 0.184984 GO:0006281 DNA repair 1 128 0.2 0.188994 GO:0004721 phosphoprotein phosphatase activity 2 491 0.7 0.189544 GO:0007049 cell cycle 2 496 0.8 0.19251 GO:0004672 protein kinase activity 2 496 0.8 0.19251 GO:0050794 regulation of cellular process 12 5831 9.4 0.196612 GO:0009987 cellular process 12 5837 9.5 0.197782 GO:0008152 metabolism 2 509 0.8 0.200256 GO:0006468 protein amino acid phosphorylation 2 514 0.8 0.203247 GO:0005856 cytoskeleton 1 139 0.2 0.203534 GO:0030695 GTPase regulator activity 2 517 0.8 0.205044 GO:0006950 response to stress 1 148 0.2 0.215245 GO:0008289 lipid binding 1 149 0.2 0.216536 GO:0006974 response to DNA damage stimulus 1 157 0.2 0.226791 GO:0004252 serine-type endopeptidase activity 1 157 0.2 0.226791 GO:0009719 response to endogenous stimulus 1 159 0.2 0.229334 GO:0006066 alcohol metabolism 2 559 0.9 0.230402 GO:0016310 phosphorylation 1 160 0.2 0.230603 GO:0003779 actin binding 1 161 0.2 0.23187 GO:0015291 porter activity 2 2374 3.8 0.231885 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 162 0.2 0.233135 GO:0015290 electrochemical potential-driven transporter activity 2 2359 3.8 0.235932 u GO:0004872 receptor activity 1 169 0.2 0.241933 GO:0008236 serine-type peptidase activity 1 1604 2.6 0.246602 u GO:0003677 DNA binding 2 586 0.9 0.24685 GO:0016773 phosphotransferase activity, alcohol group as acceptor 3 1067 1.7 0.249522 GO:0005524 ATP binding 2 594 0.9 0.251739 GO:0016788 hydrolase activity, acting on ester bonds 1 178 0.2 0.253103 GO:0007276 gametogenesis 3 1078 1.7 0.254441 GO:0030554 adenyl nucleotide binding 2 599 0.9 0.254797 GO:0016491 oxidoreductase activity 3 2958 4.8 0.259685 u GO:0004871 signal transducer activity 1 185 0.3 0.261682 GO:0006396 RNA processing 1 187 0.3 0.264116 GO:0016791 phosphoric monoester hydrolase activity 2 619 1 0.267045 GO:0008283 cell proliferation 2 632 1 0.275015 GO:0005739 mitochondrion 2 634 1 0.276241 GO:0005886 plasma membrane 1 200 0.3 0.279749 GO:0005829 cytosol 1 211 0.3 0.292728 GO:0004518 nuclease activity 2 698 1.1 0.31545 GO:0009887 organogenesis 3 1221 1.9 0.319608 GO:0046914 transition metal ion binding 1 235 0.3 0.320275 GO:0009613 response to pest/pathogen/parasite 1 238 0.3 0.323645 GO:0016070 RNA metabolism 1 243 0.3 0.329227 GO:0042578 phosphoric ester hydrolase activity 1 244 0.3 0.330338 GO:0006996 organelle organization and biogenesis 2 2048 3.3 0.331753 u GO:0050789 regulation of biological process 1 259 0.4 0.346794 GO:0007399 neurogenesis 1 262 0.4 0.350038 GO:0019752 carboxylic acid metabolism 1 265 0.4 0.353267 GO:0006082 organic acid metabolism 2 771 1.2 0.35976 GO:0016772 transferase activity, transferring phosphorus-containing groups 2 797 1.2 0.375351 GO:0009056 catabolism 1 286 0.4 0.375444 GO:0007028 cytoplasm organization and biogenesis 3 1366 2.2 0.386561 GO:0017076 purine nucleotide binding 1 297 0.4 0.386768 GO:0030001 metal ion transport 2 822 1.3 0.39022 GO:0009653 morphogenesis 3 1374 2.2 0.390242 GO:0000166 nucleotide binding 1 311 0.5 0.400897 GO:0005386 carrier activity 1 321 0.5 0.410798 GO:0046907 intracellular transport 1 327 0.5 0.416663 GO:0005783 endoplasmic reticulum 14 9173 14.9 0.416977 u GO:0005623 cell 1 384 0.6 0.469667 GO:0030234 enzyme regulator activity 1 390 0.6 0.47497 GO:0007155 cell adhesion 1 399 0.6 0.48283 GO:0006812 cation transport 1 433 0.7 0.511519 GO:0005102 receptor binding 2 1058 1.7 0.522463 GO:0050896 response to stimulus 1 456 0.7 0.530057 GO:0004175 endopeptidase activity 2 1095 1.7 0.541588 GO:0008270 zinc ion binding 1 500 0.8 0.563662 GO:0005509 calcium ion binding 1 505 0.8 0.567332 GO:0006259 DNA metabolism 2 1147 1.8 0.567639 GO:0005215 transporter activity 1 879 1.4 0.576399 u GO:0009605 response to external stimulus 2 1372 2.2 0.610678 u GO:0016740 transferase activity 1 578 0.9 0.617663 GO:0009607 response to biotic stimulus 1 582 0.9 0.620253 GO:0016043 cell organization and biogenesis 1 590 0.9 0.625381 GO:0006508 proteolysis and peptidolysis 1 610 0.9 0.637915 GO:0030163 protein catabolism 1 613 0.9 0.63976 GO:0009057 macromolecule catabolism 1 723 1.1 0.669303 u GO:0005576 extracellular 1 660 1 0.707814 u GO:0007242 intracellular signaling cascade 1 625 1 0.729277 u GO:0005198 structural molecule activity 1 622 1 0.731117 u GO:0008233 peptidase activity 1 620 1 0.732342 u GO:0006811 ion transport