# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 42 #b referenced loci : 40 #c annotated loci : 31 #d hyper-geometric : n 31 hgN 14129 #e k hgK Exp k p-value term description 4 212 0.4 0.00112826 GO:0016192 vesicle-mediated transport 2 24 0 0.00124776 GO:0030100 regulation of endocytosis 24 7041 15.4 0.00155242 GO:0005488 binding 3 117 0.2 0.00210067 GO:0006897 endocytosis 11 2064 4.5 0.00316547 GO:0005515 protein binding 1 2 0 0.00438348 GO:0000209 protein polyubiquitination 1 2 0 0.00438348 GO:0001786 phosphatidylserine binding 1 2 0 0.00438348 GO:0004020 adenylyl-sulfate kinase activity 1 2 0 0.00438348 GO:0004779 sulfate adenylyltransferase activity 1 2 0 0.00438348 GO:0004781 sulfate adenylyltransferase (ATP) activity 1 2 0 0.00438348 GO:0008429 phosphatidylethanolamine binding 2 49 0.1 0.00513832 GO:0051049 regulation of transport 1 3 0 0.00656824 GO:0004652 polynucleotide adenylyltransferase activity 1 3 0 0.00656824 GO:0042147 retrograde transport, endosome to Golgi 1 3 0 0.00656824 GO:0043149 stress fiber formation 1 3 0 0.00656824 GO:0045806 negative regulation of endocytosis 1 3 0 0.00656824 GO:0048041 focal adhesion formation 4 350 0.7 0.00686683 GO:0006629 lipid metabolism 9 1656 3.6 0.00744691 GO:0006810 transport 2 3552 7.7 0.00802126 u GO:0016021 integral to membrane 1 4 0 0.00874836 GO:0000103 sulfate assimilation 1 4 0 0.00874836 GO:0003997 acyl-CoA oxidase activity 1 4 0 0.00874836 GO:0006791 sulfur utilization 1 4 0 0.00874836 GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors 8 1415 3.1 0.00959183 GO:0007275 development 1 5 0 0.0109239 GO:0004287 prolyl oligopeptidase activity 1 5 0 0.0109239 GO:0006910 phagocytosis, recognition 1 5 0 0.0109239 GO:0017137 Rab interactor activity 25 8414 18.4 0.0109883 GO:0007582 physiological process 7 1161 2.5 0.0113328 GO:0006464 protein modification 1 6 0 0.0130947 GO:0001725 stress fiber 1 6 0 0.0130947 GO:0051051 negative regulation of transport 1 7 0 0.015261 GO:0045444 adipocyte differentiation 1 7 0 0.015261 GO:0051017 actin filament bundle formation 2 92 0.2 0.0172524 GO:0005083 small GTPase regulatory/interacting protein activity 1 8 0 0.0174226 GO:0006635 fatty acid beta-oxidation 1 8 0 0.0174226 GO:0006911 phagocytosis, engulfment 1 8 0 0.0174226 GO:0019905 syntaxin binding 16 4537 9.9 0.0187705 GO:0003824 catalytic activity 2 97 0.2 0.01906 GO:0006397 mRNA processing 1 9 0 0.0195797 GO:0000086 G2/M transition of mitotic cell cycle 1 9 0 0.0195797 GO:0009618 response to pathogenic bacteria 1 9 0 0.0195797 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 3 264 0.5 0.0197131 GO:0016567 protein ubiquitination 3 268 0.5 0.0205055 GO:0000151 ubiquitin ligase complex 1 10 0 0.0217322 GO:0005178 integrin binding 1 10 0 0.0217322 GO:0005913 cell-cell adherens junction 1 10 0 0.0217322 GO:0016358 dendrite morphogenesis 5 749 1.6 0.0223083 GO:0016301 kinase activity 2 106 0.2 0.0225054 GO:0016071 mRNA metabolism 1 11 0 0.0238801 GO:0000149 SNARE binding 1 11 0 0.0238801 GO:0005158 insulin receptor binding 1 11 0 0.0238801 GO:0005802 Golgi trans face 1 11 0 0.0238801 GO:0008645 hexose transport 1 11 0 0.0238801 GO:0015749 monosaccharide transport 1 11 0 0.0238801 GO:0015758 glucose transport 5 771 1.6 0.024931 GO:0016772 transferase activity, transferring phosphorus-containing groups 4 514 1.1 0.0250216 GO:0005856 cytoskeleton 1 12 0 0.0260234 GO:0004179 membrane alanyl aminopeptidase activity 1 12 0 0.0260234 GO:0016284 alanine aminopeptidase activity 1 12 0 0.0260234 GO:0050764 regulation of phagocytosis 1 12 0 0.0260234 GO:0050766 positive regulation of phagocytosis 6 1067 2.3 0.0263445 GO:0005524 ATP binding 18 5553 12.1 0.0264519 GO:0005622 intracellular 10 2384 5.2 0.0267423 GO:0019538 protein metabolism 2 118 0.2 0.0274675 GO:0000278 mitotic cell cycle 6 1078 2.3 0.0275457 GO:0030554 adenyl nucleotide binding 2 119 0.2 0.0278993 GO:0007243 protein kinase cascade 1 13 0 0.0281622 GO:0016197 endosome transport 1 13 0 0.0281622 GO:0019395 fatty acid oxidation 1 13 0 0.0281622 GO:0045121 lipid raft 3 307 0.6 0.0291519 GO:0004842 ubiquitin-protein ligase activity 1 14 0 0.0302965 GO:0005924 cell-substrate adherens junction 1 14 0 0.0302965 GO:0045807 positive regulation of endocytosis 1 14 0 0.0302965 GO:0046777 autophosphorylation 1 15 0 0.0324262 GO:0004722 protein serine/threonine phosphatase activity 1 15 0 0.0324262 GO:0008286 insulin receptor signaling pathway 3 326 0.7 0.0339684 GO:0016881 acid-D-amino acid ligase activity 1 16 0 0.0345513 GO:0006289 nucleotide-excision repair 1 16 0 0.0345513 GO:0030055 cell-matrix junction 2 136 0.2 0.0356519 GO:0016779 nucleotidyltransferase activity 1 17 0 0.036672 GO:0007032 endosome organization and biogenesis 2 139 0.3 0.037098 GO:0030695 GTPase regulator activity 4 586 1.2 0.0379501 GO:0016773 phosphotransferase activity, alcohol group as acceptor 2 141 0.3 0.0380745 GO:0000287 magnesium ion binding 1 18 0 0.0387882 GO:0007015 actin filament organization 1 18 0 0.0387882 GO:0051050 positive regulation of transport 3 345 0.7 0.0391775 GO:0004674 protein serine/threonine kinase activity 1 20 0 0.043007 GO:0006909 phagocytosis 3 360 0.7 0.0435644 GO:0016879 ligase activity, forming carbon-nitrogen bonds 18 5837 12.8 0.0443291 GO:0008152 metabolism 8 1874 4.1 0.0448635 GO:0046872 metal ion binding 1 21 0 0.0451097 GO:0000082 G1/S transition of mitotic cell cycle 1 21 0 0.0451097 GO:0008287 protein serine/threonine phosphatase complex 3 368 0.8 0.0460019 GO:0006512 ubiquitin cycle 1 22 0 0.0472079 GO:0019901 protein kinase binding 1 23 0 0.0493016 GO:0005905 coated pit 2 2672 5.8 0.0502975 u GO:0003676 nucleic acid binding 1 24 0 0.0513909 GO:0007338 fertilization (sensu Animalia) 1 24 0 0.0513909 GO:0009566 fertilization 1 24 0 0.0513909 GO:0019900 kinase binding 1 25 0 0.0534758 GO:0007249 I-kappaB kinase/NF-kappaB cascade 1 25 0 0.0534758 GO:0009617 response to bacteria 4 669 1.4 0.0569223 GO:0006793 phosphorus metabolism 4 669 1.4 0.0569223 GO:0006796 phosphate metabolism 1 27 0 0.0576322 GO:0008643 carbohydrate transport 10 2707 5.9 0.0581513 GO:0005737 cytoplasm 1 28 0 0.0597038 GO:0004177 aminopeptidase activity 1 28 0 0.0597038 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2 185 0.4 0.0618917 GO:0006396 RNA processing 1 1922 4.2 0.0630239 u GO:0007166 cell surface receptor linked signal transduction 10 2750 6 0.0637118 GO:0008151 cell growth and/or maintenance 1 32 0 0.0679461 GO:0005912 adherens junction 1 34 0 0.072041 GO:0008203 cholesterol metabolism 2 203 0.4 0.0727853 GO:0000003 reproduction 2 203 0.4 0.0727853 GO:0019953 sexual reproduction 6 1366 2.9 0.0730635 GO:0017076 purine nucleotide binding 6 1374 3 0.0747367 GO:0000166 nucleotide binding 1 37 0 0.0781507 GO:0005319 lipid transporter activity 3 460 1 0.0787233 GO:0016874 ligase activity 1 38 0 0.0801787 GO:0016125 sterol metabolism 1 39 0 0.0822023 GO:0005543 phospholipid binding 2 222 0.4 0.0849069 GO:0008092 cytoskeletal protein binding 6 4555 9.9 0.0855818 u GO:0016020 membrane 1 42 0 0.0882472 GO:0030145 manganese ion binding 2 2359 5.1 0.089665 u GO:0004872 receptor activity 1 43 0 0.0902536 GO:0006790 sulfur metabolism 3 496 1 0.0937223 GO:0004672 protein kinase activity 2 238 0.5 0.0955617 GO:0016070 RNA metabolism 3 509 1.1 0.0994165 GO:0006468 protein amino acid phosphorylation 2 244 0.5 0.0996542 GO:0006996 organelle organization and biogenesis 1 48 0.1 0.100222 GO:0008235 metalloexopeptidase activity 1 48 0.1 0.100222 GO:0009897 external side of plasma membrane 1 48 0.1 0.100222 GO:0019897 extrinsic to plasma membrane 1 49 0.1 0.102203 GO:0019898 extrinsic to membrane 3 517 1.1 0.102991 GO:0006950 response to stress 1 51 0.1 0.106152 GO:0005615 extracellular space 1 51 0.1 0.106152 GO:0005941 unlocalized 1 51 0.1 0.106152 GO:0016042 lipid catabolism 1 53 0.1 0.110084 GO:0006869 lipid transport 1 53 0.1 0.110084 GO:0019899 enzyme binding 1 54 0.1 0.112044 GO:0000375 RNA splicing, via transesterification reactions 1 54 0.1 0.112044 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1 54 0.1 0.112044 GO:0000398 nuclear mRNA splicing, via spliceosome 1 54 0.1 0.112044 GO:0005777 peroxisome 1 54 0.1 0.112044 GO:0042579 microbody 1 55 0.1 0.114 GO:0007160 cell-matrix adhesion 1 1604 3.5 0.118307 u GO:0003677 DNA binding 3 559 1.2 0.122591 GO:0016310 phosphorylation 3 2728 5.9 0.124707 u GO:0007165 signal transduction 5 1221 2.6 0.124709 GO:0046914 transition metal ion binding 2 280 0.6 0.12519 GO:0005794 Golgi apparatus 10 3131 6.8 0.128972 GO:0050875 cellular physiological process 1 63 0.1 0.129496 GO:0030036 actin cytoskeleton organization and biogenesis 2 286 0.6 0.129592 GO:0007028 cytoplasm organization and biogenesis 1 65 0.1 0.133329 GO:0015293 symporter activity 2 294 0.6 0.13552 GO:0030154 cell differentiation 1 67 0.1 0.137146 GO:0008380 RNA splicing 1 67 0.1 0.137146 GO:0030029 actin filament-based process 1 1516 3.3 0.139799 u GO:0006350 transcription 1 70 0.1 0.14284 GO:0006816 calcium ion transport 4 3170 6.9 0.143227 u GO:0007154 cell communication 1 73 0.1 0.148498 GO:0005875 microtubule associated complex 1 74 0.1 0.150376 GO:0001501 skeletal development 1 74 0.1 0.150376 GO:0005516 calmodulin binding 1 75 0.1 0.15225 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 2 2048 4.4 0.152602 u GO:0050789 regulation of biological process 1 79 0.1 0.159706 GO:0007517 muscle development 3 634 1.3 0.160707 GO:0005886 plasma membrane 1 82 0.1 0.165256 GO:0008202 steroid metabolism 1 82 0.1 0.165256 GO:0009986 cell surface 1 83 0.1 0.167098 GO:0008238 exopeptidase activity 2 337 0.7 0.168359 GO:0006118 electron transport 5 1372 3 0.17737 GO:0016740 transferase activity 1 92 0.2 0.183502 GO:0006631 fatty acid metabolism 2 358 0.7 0.184884 GO:0015031 protein transport 1 95 0.2 0.1889 GO:0007283 spermatogenesis 1 95 0.2 0.1889 GO:0048232 male gamete generation 1 96 0.2 0.190691 GO:0005911 intercellular junction 4 2958 6.4 0.19223 u GO:0004871 signal transducer activity 6 1795 3.9 0.193405 GO:0016787 hydrolase activity 3 698 1.5 0.195827 GO:0009887 organogenesis 1 102 0.2 0.201361 GO:0019866 inner membrane 2 384 0.8 0.205673 GO:0030234 enzyme regulator activity 2 390 0.8 0.210512 GO:0007155 cell adhesion 3 2374 5.2 0.210816 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 110 0.2 0.215376 GO:0006470 protein amino acid dephosphorylation 1 110 0.2 0.215376 GO:0015674 di-, tri-valent inorganic cation transport 4 1095 2.4 0.216363 GO:0008270 zinc ion binding 1 111 0.2 0.217111 GO:0016327 apicolateral plasma membrane 1 112 0.2 0.218842 GO:0016311 dephosphorylation 1 118 0.2 0.229153 GO:0007167 enzyme linked receptor protein signaling pathway 1 119 0.2 0.230858 GO:0030054 cell junction 1 125 0.2 0.241015 GO:0006281 DNA repair 2 433 0.9 0.245514 GO:0005102 receptor binding 1 128 0.2 0.246045 GO:0004721 phosphoprotein phosphatase activity 1 130 0.2 0.24938 GO:0015629 actin cytoskeleton 1 131 0.2 0.251042 GO:0003774 motor activity 3 797 1.7 0.253529 GO:0009056 catabolism 1 138 0.3 0.262578 GO:0015630 microtubule cytoskeleton 3 822 1.8 0.268555 GO:0009653 morphogenesis 1 148 0.3 0.27876 GO:0008289 lipid binding 1 149 0.3 0.28036 GO:0006974 response to DNA damage stimulus 1 157 0.3 0.29303 GO:0004252 serine-type endopeptidase activity 1 157 0.3 0.29303 GO:0009719 response to endogenous stimulus 2 491 1 0.293134 GO:0007049 cell cycle 1 158 0.3 0.294599 GO:0008237 metallopeptidase activity 1 159 0.3 0.296164 GO:0006066 alcohol metabolism 2 496 1 0.297238 GO:0050794 regulation of cellular process 1 160 0.3 0.297726 GO:0003779 actin binding 1 161 0.3 0.299284 GO:0015291 porter activity 1 162 0.3 0.300839 GO:0015290 electrochemical potential-driven transporter activity 1 166 0.3 0.307027 GO:0006457 protein folding 1 169 0.3 0.311632 GO:0008236 serine-type peptidase activity 1 178 0.3 0.325272 GO:0007276 gametogenesis 1 187 0.4 0.33865 GO:0016791 phosphoric monoester hydrolase activity 1 200 0.4 0.357522 GO:0005829 cytosol 1 204 0.4 0.363223 GO:0007010 cytoskeleton organization and biogenesis 2 582 1.2 0.367135 GO:0016043 cell organization and biogenesis 1 211 0.4 0.373082 GO:0004518 nuclease activity 2 590 1.2 0.373535 GO:0006508 proteolysis and peptidolysis 2 594 1.3 0.376727 GO:0016788 hydrolase activity, acting on ester bonds 2 599 1.3 0.380708 GO:0016491 oxidoreductase activity 2 610 1.3 0.389433 GO:0030163 protein catabolism 2 613 1.3 0.391804 GO:0009057 macromolecule catabolism 14 5831 12.7 0.394613 GO:0009987 cellular process 2 619 1.3 0.396535 GO:0008283 cell proliferation 2 622 1.3 0.398896 GO:0008233 peptidase activity 1 235 0.5 0.405776 GO:0009613 response to pest/pathogen/parasite 2 632 1.3 0.406734 GO:0005739 mitochondrion 3 1058 2.3 0.412934 GO:0050896 response to stimulus 1 243 0.5 0.416303 GO:0042578 phosphoric ester hydrolase activity 1 879 1.9 0.417042 u GO:0009605 response to external stimulus 2 660 1.4 0.428442 GO:0007242 intracellular signaling cascade 1 259 0.5 0.436818 GO:0007399 neurogenesis 1 262 0.5 0.440586 GO:0019752 carboxylic acid metabolism 1 265 0.5 0.44433 GO:0006082 organic acid metabolism 21 9173 20.1 0.451523 GO:0005623 cell 5 2670 5.8 0.453681 u GO:0005634 nucleus 1 297 0.6 0.482783 GO:0030001 metal ion transport 1 311 0.6 0.498784 GO:0005386 carrier activity 1 321 0.7 0.50992 GO:0046907 intracellular transport 1 327 0.7 0.516486 GO:0005783 endoplasmic reticulum 1 723 1.5 0.524171 u GO:0005576 extracellular 2 1147 2.5 0.533865 u GO:0005215 transporter activity 1 375 0.8 0.566035 GO:0003723 RNA binding 1 399 0.8 0.588929 GO:0006812 cation transport 1 625 1.3 0.598748 u GO:0005198 structural molecule activity 1 620 1.3 0.602677 u GO:0006811 ion transport 1 578 1.2 0.636073 u GO:0009607 response to biotic stimulus 1 505 1.1 0.695381 u GO:0006259 DNA metabolism 1 500 1 0.69948 u GO:0005509 calcium ion binding 1 456 1 0.73562 u GO:0004175 endopeptidase activity