# /cluster/home/jill/chuck/mm5/pval/go/bg/kgJillIsoforms.tab 41208, /cluster/home/jill/chuck/mm5/pval/go/bg/kgMrnaGo.tab 92287, /cluster/home/jill/chuck/mm5/pval/go/bg/goKgAncestors.tab 3801, /cluster/home/jill/chuck/mm5/pval/go/bg/mm5.knownGene.out 5087 #a instance list : 82 #b referenced loci : 79 #c annotated loci : 71 #d hyper-geometric : n 71 hgN 14129 #e k hgK Exp k p-value term description 24 2064 10.3 3.91076e-05 GO:0005515 protein binding 3 21 0.1 0.00015156 GO:0043087 regulation of GTPase activity 10 514 2.5 0.000233665 GO:0005856 cytoskeleton 2 6 0 0.000368632 GO:0019894 kinesin binding 1 1922 9.6 0.000369112 u GO:0007166 cell surface receptor linked signal transduction 4 73 0.3 0.000490599 GO:0005875 microtubule associated complex 5 138 0.6 0.000641812 GO:0015630 microtubule cytoskeleton 5 2958 14.8 0.00128474 u GO:0004871 signal transducer activity 48 7041 35.3 0.00181798 GO:0005488 binding 1 1597 8 0.00197711 u GO:0007186 G-protein coupled receptor protein signaling pathway 3 50 0.2 0.00201239 GO:0050790 regulation of enzyme activity 15 1366 6.8 0.00282724 GO:0017076 purine nucleotide binding 15 1374 6.9 0.00299104 GO:0000166 nucleotide binding 6 286 1.4 0.00310686 GO:0007028 cytoplasm organization and biogenesis 10 749 3.7 0.00405855 GO:0016301 kinase activity 4 2359 11.8 0.0049122 u GO:0004872 receptor activity 1 1 0 0.00502513 GO:0004438 phosphatidylinositol-3-phosphatase activity 1 1 0 0.00502513 GO:0007274 neuromuscular synaptic transmission 1 1 0 0.00502513 GO:0008089 anterograde axon cargo transport 1 1 0 0.00502513 GO:0016939 kinesin II complex 1 1 0 0.00502513 GO:0019987 negative regulation of anti-apoptosis 1 1 0 0.00502513 GO:0030325 adrenal gland development 5 222 1.1 0.00514166 GO:0008092 cytoskeletal protein binding 3 74 0.3 0.00610828 GO:0005516 calmodulin binding 12 1067 5.3 0.00650503 GO:0005524 ATP binding 12 1078 5.4 0.00704468 GO:0030554 adenyl nucleotide binding 5 244 1.2 0.00760938 GO:0006996 organelle organization and biogenesis 9 3552 17.8 0.00776535 u GO:0016021 integral to membrane 8 582 2.9 0.00857746 GO:0016043 cell organization and biogenesis 3 84 0.4 0.00866416 GO:0007017 microtubule-based process 1 2 0 0.0100254 GO:0000209 protein polyubiquitination 1 2 0 0.0100254 GO:0001672 regulation of chromatin assembly/disassembly 1 2 0 0.0100254 GO:0030517 negative regulation of axon extension 1 2 0 0.0100254 GO:0045646 regulation of erythrocyte differentiation 1 2 0 0.0100254 GO:0045648 positive regulation of erythrocyte differentiation 12 1161 5.8 0.012359 GO:0006464 protein modification 3 102 0.5 0.0146454 GO:0045202 synapse 1 3 0 0.0150008 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1 3 0 0.0150008 GO:0004828 serine-tRNA ligase activity 1 3 0 0.0150008 GO:0005869 dynactin complex 1 3 0 0.0150008 GO:0006434 seryl-tRNA aminoacylation 1 3 0 0.0150008 GO:0042147 retrograde transport, endosome to Golgi 2 38 0.1 0.0155757 GO:0007018 microtubule-based movement 2 38 0.1 0.0155757 GO:0030705 cytoskeleton-dependent intracellular transport 8 669 3.3 0.0186284 GO:0006793 phosphorus metabolism 8 669 3.3 0.0186284 GO:0006796 phosphate metabolism 4 204 1 0.0193355 GO:0007010 cytoskeleton organization and biogenesis 1 4 0 0.0199516 GO:0007435 salivary gland morphogenesis 1 4 0 0.0199516 GO:0008088 axon cargo transport 1 4 0 0.0199516 GO:0045639 positive regulation of myeloid blood cell differentiation 1 4 0 0.0199516 GO:0045767 regulation of anti-apoptosis 1 5 0 0.0248779 GO:0000145 exocyst 1 5 0 0.0248779 GO:0007044 cell-substrate junction assembly 1 5 0 0.0248779 GO:0008717 D-alanyl-D-alanine endopeptidase activity 1 5 0 0.0248779 GO:0017137 Rab interactor activity 1 5 0 0.0248779 GO:0030516 regulation of axon extension 1 5 0 0.0248779 GO:0030865 cortical cytoskeleton organization and biogenesis 1 5 0 0.0248779 GO:0030866 cortical actin cytoskeleton organization and biogenesis 2 49 0.2 0.0251508 GO:0005789 endoplasmic reticulum membrane 2 50 0.2 0.0261149 GO:0042175 nuclear envelope-endoplasmic reticulum network 3 131 0.6 0.0281877 GO:0003774 motor activity 5 345 1.7 0.0295845 GO:0004674 protein serine/threonine kinase activity 1 6 0 0.0297797 GO:0001658 ureteric bud branching 1 6 0 0.0297797 GO:0007270 nerve-nerve synaptic transmission 1 6 0 0.0297797 GO:0007431 salivary gland development 1 6 0 0.0297797 GO:0042577 lipid phosphatase activity 3 139 0.6 0.0327822 GO:0030695 GTPase regulator activity 1 7 0 0.0346573 GO:0005388 calcium-transporting ATPase activity 1 7 0 0.0346573 GO:0015085 calcium ion transporter activity 6 496 2.4 0.0381629 GO:0004672 protein kinase activity 2 62 0.3 0.0387953 GO:0004840 ubiquitin conjugating enzyme activity 2 62 0.3 0.0387953 GO:0008639 small protein conjugating enzyme activity 1 8 0 0.0395106 GO:0005871 kinesin complex 1 8 0 0.0395106 GO:0030218 erythrocyte differentiation 1 8 0 0.0395106 GO:0030659 cytoplasmic vesicle membrane 3 152 0.7 0.0410304 GO:0000067 DNA replication and chromosome cycle 20 2707 13.6 0.0419054 GO:0005737 cytoplasm 6 509 2.5 0.0424199 GO:0006468 protein amino acid phosphorylation 1 9 0 0.0443399 GO:0016581 NuRD complex 3 157 0.7 0.0444569 GO:0012505 endomembrane system 2 70 0.3 0.0482989 GO:0006816 calcium ion transport 16 4555 22.8 0.0487644 u GO:0016020 membrane 1 10 0 0.0491453 GO:0001763 branching morphogenesis 1 10 0 0.0491453 GO:0004685 calcium/calmodulin-dependent protein kinase activity 1 10 0 0.0491453 GO:0042060 wound healing 8 2728 13.7 0.0518166 u GO:0007165 signal transduction 1 11 0 0.0539269 GO:0001657 ureteric bud development 1 11 0 0.0539269 GO:0042472 inner ear morphogenesis 1 11 0 0.0539269 GO:0051052 regulation of DNA metabolism 35 5553 27.9 0.0552046 GO:0005622 intracellular 1 12 0 0.0586847 GO:0007189 G-protein signaling, adenylate cyclase activating pathway 1 12 0 0.0586847 GO:0042471 ear morphogenesis 6 559 2.8 0.0615375 GO:0016310 phosphorylation 1 13 0 0.063419 GO:0005938 cell cortex 1 13 0 0.063419 GO:0006446 regulation of translational initiation 1 13 0 0.063419 GO:0007548 sex differentiation 1 13 0 0.063419 GO:0016197 endosome transport 1 13 0 0.063419 GO:0016998 cell wall catabolism 1 13 0 0.063419 GO:0042493 response to drug 2 1147 5.7 0.0649067 u GO:0005215 transporter activity 1 14 0 0.0681297 GO:0004683 calmodulin regulated protein kinase activity 1 14 0 0.0681297 GO:0006700 C21-steroid hormone biosynthesis 1 14 0 0.0681297 GO:0012506 vesicle membrane 1 14 0 0.0681297 GO:0046777 autophosphorylation 4 307 1.5 0.0685333 GO:0004842 ubiquitin-protein ligase activity 1 15 0 0.0728171 GO:0008207 C21-steroid hormone metabolism 1 15 0 0.0728171 GO:0045637 regulation of myeloid blood cell differentiation 6 586 2.9 0.0737075 GO:0016773 phosphotransferase activity, alcohol group as acceptor 1 16 0 0.0774813 GO:0005520 insulin-like growth factor binding 1 16 0 0.0774813 GO:0007059 chromosome segregation 1 16 0 0.0774813 GO:0030176 integral to endoplasmic reticulum membrane 4 321 1.6 0.0779012 GO:0046907 intracellular transport 2 92 0.4 0.078084 GO:0005083 small GTPase regulatory/interacting protein activity 5 460 2.3 0.0812919 GO:0016874 ligase activity 4 326 1.6 0.0813963 GO:0016881 acid-D-amino acid ligase activity 1 17 0 0.0821223 GO:0000118 histone deacetylase complex 1 17 0 0.0821223 GO:0007032 endosome organization and biogenesis 1 17 0 0.0821223 GO:0016323 basolateral plasma membrane 15 2048 10.2 0.0821478 GO:0050789 regulation of biological process 1 18 0 0.0867403 GO:0001656 metanephros development 1 18 0 0.0867403 GO:0001822 kidney development 1 18 0 0.0867403 GO:0004437 inositol/phosphatidylinositol phosphatase activity 1 18 0 0.0867403 GO:0042446 hormone biosynthesis 1 19 0 0.0913354 GO:0001655 urogenital system development 1 19 0 0.0913354 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 1 19 0 0.0913354 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 1 19 0 0.0913354 GO:0030286 dynein complex 1 20 0.1 0.0959077 GO:0045597 positive regulation of cell differentiation 5 491 2.4 0.10041 GO:0007049 cell cycle 1 21 0.1 0.100457 GO:0000082 G1/S transition of mitotic cell cycle 4 358 1.7 0.105558 GO:0015031 protein transport 2 110 0.5 0.10568 GO:0006470 protein amino acid dephosphorylation 2 110 0.5 0.10568 GO:0015674 di-, tri-valent inorganic cation transport 5 500 2.5 0.106355 GO:0005509 calcium ion binding 4 360 1.8 0.107167 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2 112 0.5 0.108892 GO:0016311 dephosphorylation 9 2672 13.4 0.11309 u GO:0003676 nucleic acid binding 6 660 3.3 0.113665 GO:0007242 intracellular signaling cascade 4 368 1.8 0.113717 GO:0006512 ubiquitin cycle 1 24 0.1 0.113971 GO:0003777 microtubule motor activity 1 24 0.1 0.113971 GO:0006112 energy reserve metabolism 1 24 0.1 0.113971 GO:0006953 acute-phase response 1 24 0.1 0.113971 GO:0015082 di-, tri-valent inorganic cation transporter activity 1 24 0.1 0.113971 GO:0019933 cAMP-mediated signaling 5 517 2.5 0.118052 GO:0006950 response to stress 1 25 0.1 0.118431 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1 25 0.1 0.118431 GO:0008017 microtubule binding 2 118 0.5 0.118682 GO:0000278 mitotic cell cycle 2 119 0.5 0.120335 GO:0007243 protein kinase cascade 2 119 0.5 0.120335 GO:0009790 embryonic development 3 243 1.2 0.123181 GO:0042578 phosphoric ester hydrolase activity 2 122 0.6 0.125328 GO:0007268 synaptic transmission 1 27 0.1 0.127285 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1 27 0.1 0.127285 GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity 4 384 1.9 0.127338 GO:0030234 enzyme regulator activity 1 28 0.1 0.131679 GO:0019935 cyclic-nucleotide-mediated signaling 4 390 1.9 0.132619 GO:0007155 cell adhesion 16 2384 11.9 0.132958 GO:0019538 protein metabolism 2 127 0.6 0.133758 GO:0043037 translation 18 2750 13.8 0.13532 GO:0008151 cell growth and/or maintenance 2 128 0.6 0.13546 GO:0004721 phosphoprotein phosphatase activity 2 128 0.6 0.13546 GO:0019226 transmission of nerve impulse 2 128 0.6 0.13546 GO:0050905 neuromuscular physiological process 2 129 0.6 0.137166 GO:0006260 DNA replication 1 30 0.1 0.140401 GO:0015631 tubulin binding 1 31 0.1 0.14473 GO:0019838 growth factor binding 1 33 0.1 0.153323 GO:0005200 structural constituent of cytoskeleton 3 270 1.3 0.154273 GO:0005578 extracellular matrix 1 34 0.1 0.157588 GO:0006887 exocytosis 2 144 0.7 0.163297 GO:0050793 regulation of development 1 37 0.1 0.170255 GO:0007411 axon guidance 1 37 0.1 0.170255 GO:0019932 second-messenger-mediated signaling 2 149 0.7 0.172201 GO:0006974 response to DNA damage stimulus 3 286 1.4 0.173765 GO:0005525 GTP binding 2 151 0.7 0.175785 GO:0007267 cell-cell signaling 1 39 0.1 0.178595 GO:0006418 tRNA aminoacylation for protein translation 1 39 0.1 0.178595 GO:0030099 myeloid blood cell differentiation 1 39 0.1 0.178595 GO:0042445 hormone metabolism 1 39 0.1 0.178595 GO:0043038 amino acid activation 1 39 0.1 0.178595 GO:0043039 tRNA aminoacylation 1 613 3 0.180252 u GO:0009057 macromolecule catabolism 1 610 3 0.182406 u GO:0030163 protein catabolism 1 40 0.2 0.182734 GO:0000165 MAPKKK cascade 1 40 0.2 0.182734 GO:0006445 regulation of translation 3 294 1.4 0.183767 GO:0019001 guanyl nucleotide binding 42 9173 46 0.184381 u GO:0005623 cell 2 157 0.7 0.186608 GO:0009719 response to endogenous stimulus 1 41 0.2 0.186853 GO:0004812 tRNA ligase activity 1 41 0.2 0.186853 GO:0006694 steroid biosynthesis 1 41 0.2 0.186853 GO:0008201 heparin binding 1 41 0.2 0.186853 GO:0008452 RNA ligase activity 1 41 0.2 0.186853 GO:0016875 ligase activity, forming carbon-oxygen bonds 1 41 0.2 0.186853 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds 6 771 3.8 0.190227 GO:0016772 transferase activity, transferring phosphorus-containing groups 1 599 3 0.190501 u GO:0016491 oxidoreductase activity 1 42 0.2 0.190951 GO:0006400 tRNA modification 1 42 0.2 0.190951 GO:0006413 translational initiation 1 42 0.2 0.190951 GO:0006986 response to unfolded protein 2 160 0.8 0.192056 GO:0003779 actin binding 2 162 0.8 0.1957 GO:0004713 protein-tyrosine kinase activity 1 590 2.9 0.197356 u GO:0006508 proteolysis and peptidolysis 1 44 0.2 0.199086 GO:0007420 brain development 5 619 3.1 0.199695 GO:0008283 cell proliferation 1 46 0.2 0.207141 GO:0009795 embryonic morphogenesis 1 47 0.2 0.211138 GO:0005262 calcium channel activity 1 47 0.2 0.211138 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1 47 0.2 0.211138 GO:0016886 ligase activity, forming phosphoric ester bonds 1 47 0.2 0.211138 GO:0045211 postsynaptic membrane 19 3131 15.7 0.211168 GO:0050875 cellular physiological process 1 49 0.2 0.219073 GO:0009451 RNA modification 3 327 1.6 0.226503 GO:0005783 endoplasmic reticulum 1 51 0.2 0.226929 GO:0046873 metal ion transporter activity 2 797 4 0.228176 u GO:0009056 catabolism 2 183 0.9 0.23441 GO:0050879 organismal movement 2 187 0.9 0.241848 GO:0016791 phosphoric monoester hydrolase activity 1 55 0.2 0.242408 GO:0004221 ubiquitin thiolesterase activity 1 55 0.2 0.242408 GO:0004725 protein tyrosine phosphatase activity 26 4537 22.7 0.243251 GO:0003824 catalytic activity 1 56 0.2 0.24623 GO:0005539 glycosaminoglycan binding 1 56 0.2 0.24623 GO:0016563 transcriptional activator activity 13 3170 15.9 0.248618 u GO:0007154 cell communication 1 57 0.2 0.250033 GO:0004843 ubiquitin-specific protease activity 1 57 0.2 0.250033 GO:0015992 proton transport 3 345 1.7 0.250598 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1 58 0.2 0.253817 GO:0001558 regulation of cell growth 1 58 0.2 0.253817 GO:0005730 nucleolus 1 58 0.2 0.253817 GO:0006818 hydrogen transport 1 58 0.2 0.253817 GO:0006916 anti-apoptosis 4 1221 6.1 0.254315 u GO:0046914 transition metal ion binding 3 348 1.7 0.254654 GO:0016817 hydrolase activity, acting on acid anhydrides 10 1564 7.8 0.257159 GO:0019222 regulation of metabolism 1 59 0.2 0.257582 GO:0005635 nuclear membrane 1 59 0.2 0.257582 GO:0008081 phosphoric diester hydrolase activity 1 62 0.3 0.268766 GO:0005096 GTPase activator activity 1 62 0.3 0.268766 GO:0007417 central nervous system development 1 63 0.3 0.272456 GO:0007409 axonogenesis 1 63 0.3 0.272456 GO:0016568 chromatin modification 1 63 0.3 0.272456 GO:0030036 actin cytoskeleton organization and biogenesis 1 64 0.3 0.276129 GO:0003743 translation initiation factor activity 1 65 0.3 0.279783 GO:0006399 tRNA metabolism 7 1058 5.3 0.280853 GO:0050896 response to stimulus 1 66 0.3 0.283419 GO:0043066 negative regulation of apoptosis 1 66 0.3 0.283419 GO:0043069 negative regulation of programmed cell death 10 1606 8 0.284409 GO:0050791 regulation of physiological process 1 67 0.3 0.287036 GO:0030029 actin filament-based process 2 212 1 0.288479 GO:0016192 vesicle-mediated transport 1 68 0.3 0.290636 GO:0003924 GTPase activity 1 69 0.3 0.294218 GO:0016790 thiolester hydrolase activity 1 69 0.3 0.294218 GO:0045045 secretory pathway 1 70 0.3 0.297782 GO:0045595 regulation of cell differentiation 5 723 3.6 0.297786 GO:0005576 extracellular 1 71 0.3 0.301329 GO:0042625 ATPase activity, coupled to transmembrane movement of ions 1 72 0.3 0.304857 GO:0016049 cell growth 9 1458 7.3 0.308854 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 75 0.3 0.315338 GO:0008361 regulation of cell size 10 1656 8.3 0.317953 GO:0006810 transport 1 78 0.3 0.325663 GO:0040008 regulation of growth 1 456 2.2 0.327181 u GO:0004175 endopeptidase activity 10 2374 11.9 0.335018 u GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 81 0.4 0.335834 GO:0000087 M phase of mitotic cell cycle 1 81 0.4 0.335834 GO:0007067 mitosis 1 82 0.4 0.339191 GO:0008202 steroid metabolism 1 83 0.4 0.342531 GO:0007156 homophilic cell adhesion 4 1095 5.5 0.347078 u GO:0008270 zinc ion binding 1 85 0.4 0.349161 GO:0015405 P-P-bond-hydrolysis-driven transporter activity 4 594 2.9 0.349249 GO:0016788 hydrolase activity, acting on ester bonds 3 872 4.3 0.354278 u GO:0009058 biosynthesis 2 250 1.2 0.358643 GO:0016887 ATPase activity 1 88 0.4 0.358983 GO:0006417 regulation of protein biosynthesis 1 90 0.4 0.36545 GO:0008047 enzyme activator activity 1 91 0.4 0.368659 GO:0004867 serine-type endopeptidase inhibitor activity 1 92 0.4 0.371852 GO:0009889 regulation of biosynthesis 2 259 1.3 0.37495 GO:0007399 neurogenesis 2 634 3.1 0.376515 u GO:0005886 plasma membrane 2 632 3.1 0.378676 u GO:0005739 mitochondrion 2 264 1.3 0.38394 GO:0016567 protein ubiquitination 1 96 0.4 0.384466 GO:0008135 translation factor activity, nucleic acid binding 4 625 3.1 0.384995 GO:0005198 structural molecule activity 44 8414 42.2 0.386655 GO:0007582 physiological process 2 268 1.3 0.391094 GO:0000151 ubiquitin ligase complex 1 99 0.4 0.393763 GO:0045182 translation regulator activity 5 822 4.1 0.397425 GO:0009653 morphogenesis 8 1393 7 0.401113 GO:0006355 regulation of transcription, DNA-dependent 1 102 0.5 0.402921 GO:0006511 ubiquitin-dependent protein catabolism 1 102 0.5 0.402921 GO:0019941 modification-dependent protein catabolism 2 280 1.4 0.412334 GO:0005794 Golgi apparatus 1 106 0.5 0.414919 GO:0005667 transcription factor complex 1 106 0.5 0.414919 GO:0016477 cell migration 1 107 0.5 0.417882 GO:0030097 hemopoiesis 2 596 2.9 0.418949 u GO:0003700 transcription factor activity 8 1417 7.1 0.420096 GO:0006351 transcription, DNA-dependent 1 108 0.5 0.420829 GO:0006333 chromatin assembly/disassembly 28 5831 29.3 0.42594 u GO:0009987 cellular process 1 110 0.5 0.42668 GO:0000280 nuclear division 1 112 0.5 0.432473 GO:0006357 regulation of transcription from Pol II promoter 1 375 1.8 0.434159 u GO:0003723 RNA binding 7 1604 8 0.4353 u GO:0003677 DNA binding 1 113 0.5 0.435348 GO:0016337 cell-cell adhesion 1 113 0.5 0.435348 GO:0040007 growth 1 114 0.5 0.438208 GO:0015980 energy derivation by oxidation of organic compounds 1 115 0.5 0.441054 GO:0000279 M phase 2 297 1.4 0.441806 GO:0030001 metal ion transport 1 117 0.5 0.446703 GO:0008234 cysteine-type peptidase activity 8 1452 7.2 0.447754 GO:0045449 regulation of transcription 3 776 3.8 0.447813 u GO:0030528 transcription regulator activity 1 120 0.6 0.455072 GO:0006091 energy pathways 3 496 2.4 0.456809 GO:0050794 regulation of cellular process 6 1372 6.8 0.458289 u GO:0016740 transferase activity 1 123 0.6 0.463316 GO:0042221 response to chemical substance 1 124 0.6 0.466037 GO:0019028 viral capsid 4 698 3.5 0.468012 GO:0009887 organogenesis 3 505 2.5 0.468633 GO:0006259 DNA metabolism 1 125 0.6 0.468744 GO:0006281 DNA repair 1 125 0.6 0.468744 GO:0019012 virion 10 1874 9.4 0.471273 GO:0046872 metal ion binding 1 350 1.7 0.471757 u GO:0006629 lipid metabolism 1 127 0.6 0.474117 GO:0042626 ATPase activity, coupled to transmembrane movement of substances 14 2670 13.4 0.477416 GO:0005634 nucleus 1 346 1.7 0.477969 u GO:0016265 death 2 319 1.6 0.478742 GO:0050877 neurophysiological process 1 130 0.6 0.482077 GO:0015629 actin cytoskeleton 1 130 0.6 0.482077 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1 343 1.7 0.482662 u GO:0008219 cell death 1 131 0.6 0.484704 GO:0004866 endopeptidase inhibitor activity 1 131 0.6 0.484704 GO:0015399 primary active transporter activity 1 132 0.6 0.487318 GO:0006520 amino acid metabolism 1 132 0.6 0.487318 GO:0030414 protease inhibitor activity 1 135 0.6 0.49508 GO:0000902 cellular morphogenesis 8 1516 7.6 0.497872 GO:0006350 transcription 1 333 1.6 0.49852 u GO:0015267 channel/pore class transporter activity 3 724 3.6 0.503265 u GO:0009059 macromolecule biosynthesis 1 139 0.6 0.505251 GO:0016023 cytoplasmic vesicle 1 140 0.7 0.507762 GO:0005244 voltage-gated ion channel activity 1 141 0.7 0.51026 GO:0000287 magnesium ion binding 1 141 0.7 0.51026 GO:0008610 lipid biosynthesis 1 325 1.6 0.511438 u GO:0015268 alpha-type channel activity 29 5837 29.3 0.518977 u GO:0008152 metabolism 1 146 0.7 0.522565 GO:0006366 transcription from Pol II promoter 1 146 0.7 0.522565 GO:0009611 response to wounding 1 313 1.5 0.53119 u GO:0012501 programmed cell death 1 311 1.5 0.534524 u GO:0005386 carrier activity 1 309 1.5 0.537871 u GO:0006915 apoptosis 4 884 4.4 0.540208 u GO:0050874 organismal physiological process 4 879 4.4 0.54519 u GO:0009605 response to external stimulus 1 158 0.7 0.550868 GO:0006323 DNA packaging 1 158 0.7 0.550868 GO:0006325 establishment and/or maintenance of chromatin architecture 1 158 0.7 0.550868 GO:0006928 cell motility 1 301 1.5 0.551374 u GO:0005216 ion channel activity 3 578 2.9 0.559966 GO:0009607 response to biotic stimulus 1 294 1.4 0.563339 u GO:0030154 cell differentiation 2 480 2.4 0.564459 u GO:0006952 defense response 1 165 0.8 0.566607 GO:0005624 membrane fraction 1 166 0.8 0.568811 GO:0006457 protein folding 1 167 0.8 0.571003 GO:0006519 amino acid and derivative metabolism 1 170 0.8 0.577515 GO:0008324 cation transporter activity 1 171 0.8 0.579664 GO:0005654 nucleoplasm 7 1415 7.1 0.581486 u GO:0007275 development 1 172 0.8 0.581802 GO:0042981 regulation of apoptosis 9 1795 9 0.584814 u GO:0016787 hydrolase activity 1 174 0.8 0.586046 GO:0043067 regulation of programmed cell death 1 176 0.8 0.590248 GO:0004857 enzyme inhibitor activity 1 180 0.9 0.598525 GO:0000267 cell fraction 1 181 0.9 0.600569 GO:0007001 chromosome organization and biogenesis (sensu Eukarya) 1 181 0.9 0.600569 GO:0009308 amine metabolism 1 187 0.9 0.612616 GO:0006997 nuclear organization and biogenesis 2 444 2.2 0.613262 u GO:0006412 protein biosynthesis 1 265 1.3 0.614268 u GO:0006082 organic acid metabolism 3 622 3.1 0.618461 u GO:0008233 peptidase activity 1 262 1.3 0.61965 u GO:0019752 carboxylic acid metabolism 3 620 3.1 0.620765 u GO:0006811 ion transport 2 420 2.1 0.646293 u GO:0006955 immune response 1 238 1.1 0.663319 u GO:0016070 RNA metabolism 1 238 1.1 0.663319 u GO:0042623 ATPase activity, coupled 1 235 1.1 0.668844 u GO:0009613 response to pest/pathogen/parasite 2 399 2 0.675332 u GO:0006812 cation transport 1 230 1.1 0.678077 u GO:0015672 monovalent inorganic cation transport 1 224 1.1 0.689195 u GO:0015075 ion transporter activity 1 221 1.1 0.694766 u GO:0005261 cation channel activity 1 218 1 0.700346 u GO:0006886 intracellular protein transport 1 204 1 0.726446 u GO:0007264 small GTPase mediated signal transduction 1 204 1 0.726446 u GO:0009628 response to abiotic stimulus 1 200 1 0.733913 u GO:0005829 cytosol