MISSING SNR17A MISSING SNR17B YAL001C TFC3 TFC3 0.3 11 1.1 RNA polymerase transcription initiation factor TFIIIC (tau), 138 kDa subunit YAL003W EFB1 EFB1 19.1 14 52.3 Translation elongation factor EF-1beta, GDP/GTP exchange factor for Tef1p/Tef2p YAL030W SNC1 SNC1 1.6 24 2.3 Synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YBL018C YBL018C YBL018C 1.0 11 3.4 YBL026W SNP3 SNP3 2.0 15.5 4.9 YBL040C ERD2 ERD2 3.7 23 6.1 Protein required for receptor-mediated retrieval of lumenal ER protein from the secretory pathway YBL050W SEC17 SEC17 1.7 32 2 Protein that acts at many steps in the secretory pathway to attach NSF to organelle membranes, homolog of mammalian alpha-SNAP YBL059W YBL059W YBL059W 0.4 15 1.2 Protein of unknown function YBR078W ECM33 ECM33 6.8 13.5 18.6 Protein with predicted GPI-anchor, involved in cell wall structure or biosynthesis YBR082C UBC4 UBC4 9.7 24 14.9 Ubiquitin-conjugating enzyme that with Ubc5p is responsible for most of ubiquitin-dependent protein degradation of short-lived and abnormal proteins YBR090C YBR090C YBR090C 3.4 14.5 8.8 Protein of unknown function YBR119W MUD1 MUD1 0.4 14 1.1 U1 snRNP A protein (snRNA-associated protein) with 2 RNA recognition (RRM) domains YBR219C YBR219C YBR219C 1.1 10 4.2 YBR230C YBR230C YBR230C 1.8 18 3.8 Protein of unknown function YCR028C-A RIM1 RIM1 5.3 18.5 10.8 Single-stranded zinc finger DNA-binding protein required for replication in mitochondria YCR097W A1 A1 0.9 10 3.4 Homeodomain regulatory protein MATa1p, with MATalpha2p represses transcription of haploid-specific genes in diploid cells YCR097W-A A1 A1 0.9 10 3.4 Homeodomain regulatory protein MATa1p, with MATalpha2p represses transcription of haploid-specific genes in diploid cells YDL012C YDL012C YDL012C 2.7 27 3.5 Protein of unknown function YDL029W ARP2 ARP2 4.8 25 7.1 S.cerevisiae chromosome IV reading frame ORF YDL029w. YDL064W UBC9 UBC9 2.9 13 8.2 Smt3p-conjugating enzyme required for G2/M transition YDL079C MRK1 MRK1 0.1 18 0.3 Serine/threonine protein kinase with strong similarity to Mds1p YDL108W KIN28 KIN28 0.7 15 1.7 Cyclin-dependent serine/threonine protein kinase component of transcription initiation factor TFIIH, phosphorylates C-terminal domain (CTD) of Rpo21p YDL125C HNT1 HNT1 9.1 20.5 16.4 Member of the HIT family of Zn-binding proteins and the histidine triad nucleotide-binding protein family YDL189W YDL189W YDL189W 0.9 16 2.1 Protein of unknown function YDL219W YDL219W YDL219W 2.8 10 10.1 Protein of unknown function YDR005C MAF1 MAF1 0.8 17 1.7 Protein required for sorting of Mod5p YDR059C UBC5 UBC5 0.6 69.5 0.4 Ubiquitin-conjugating enzyme that with Ubc4p is responsible for most of ubiquitin-dependent protein degradation of short-lived and abnormal proteins YDR092W UBC13 UBC13 3.1 14 8.4 Ubiquitin-conjugating enzymes YDR129C SAC6 SAC6 3.5 21 6.1 Actin filament bundling protein, fimbrin, essential for polarized secretion YDR139C RUB1 RUB1 5.7 14.5 14.2 Ubiquitin-related protein, becomes conjugated to other proteins including Cdc53p in a process requiring Uba3p, Ula1p and Ubc12p YDR305C HNT2 HNT2 0.7 18 1.3 Diadenosine polyphosphate hydrolase, member of histidine triad (HIT) protein superfamily YDR367W YDR367W YDR367W 1.5 12 4.7 YDR381W YRA1 YRA1 4.8 11 16.2 Protein with RNA YDR397C NCB2 NCB2 1.8 9 8 Beta subunit of NC2 (Dr1/Drap1) repressor of class II transcription YDR424C DYN2 DYN2 3.1 19 6.1 Cytoplasmic dynein light chain YEL012W UBC8 UBC8 0.8 40 0.7 Ubiquitin-conjugating enzyme that is able to ubiquitinate histones in vitro YEL076C-A YEL076CA YEL076CA 0.3 16 1 Protein of unknown function YER003C PMI40 PMI40 2.5 11 8 Mannose-6-phosphate isomerase, generates mannose-6-phosphate for synthesis of GDP-mannose and dolichol-phosphate-mannose YER007C-A YER007CA YER007CA 3.3 12 10 Protein of unknown function MISSING YER044C-A YER093C-A YER093CA YER093CA 0.3 15 0.9 Protein of unknown function YER133W GLC7 GLC7 4.2 17.5 9.2 Protein serine/threonine phosphatase PP1 required for glucose repression, member of the PPP family of protein phosphatases YER179W DMC1 DMC1 0.1 15 0.3 Meiosis-specific recombination protein structurally related to S. cerevisiae Rad51p, Rad55p, Rad57p, and to E. coli RecA MISSING YFL034C-A YFL035C-A YFL035C-A YFL035CA 0.4 16 1 YFL039C ACT1 ACT1 21.1 17 45.5 Actin, involved in cell polarization, endocytosis, and other cytoskeletal functions YFR024C-A YFR024C-A YFR024CA 2.4 14 6.2 MISSING YFR032C-A YGL033W HOP2 HOP2 #N/A 20 #N/A Protein required for pairing of homologous chromosomes in meiosis YGL087C MMS2 MMS2 1.7 35 1.8 Protein involved in resistance to DNA damaging agents YGL137W SEC27 SEC27 2.6 19 5 Coatomer complex beta' chain (beta'-COP) of secretory pathway vesicles, required for retrograde transport from Golgi to endoplasmic reticulum, member of WD (WD-40) repeat family YGL178W MPT5 MPT5 1.0 #N/A-se #N/A Protein required for high temperature growth, recovery from alpha-factor arrest, and normal lifespan of yeast cells YGL187C COX4 COX4 4.9 17 10.7 Cytochrome-c oxidase chain IV MISSING YGL226C-A YGL232W YGL232W YGL232W 1.6 11 5.5 Protein with similarity to dihydropteroate synthase YGR001C YGR001C YGR001C 1.0 12.5 2.9 Protein of unknown function YGR029W ERV1 ERV1 2.1 12 6.4 Protein essential for mitochondrial biogenesis and cell viability YGR183C QCR9 QCR9 5.7 25 8.4 Ubiquinol cytochrome-c reductase subunit 9 (7.3 kDa protein), component of ubiquinol cytochrome-c reductase complex YGR296W YGR296W YGR296W 6.2 15 15.4 Protein with similarity to other subtelomerically-encoded proteins including Yer190p YHL050C YHL050C YHL050C 4.3 12.5 12.1 Protein with similarity to other subtelomerically-encoded proteins YHR001W-A QCR10 QCR10 2.6 28 3.3 Ubiquinol cytochrome-c reductase subunit (8.5 kDa protein), component of the ubiquinol cytochrome-c reductase complex YHR012W PEP11 PEP11 1.8 16 4.2 Protein involved in vacuolar protein sorting YHR016C YSC84 YSC84 0.2 24.5 0.5 Protein of unknown function YHR039C-B VMA10 VMA10 11.1 16 26.5 Vacuolar H(+)-ATPase (V-ATPase) 13 kDa subunit YHR041C SRB2 SRB2 1.1 10 4.3 Component of the RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YHR077C NMD2 NMD2 0.8 21 1.4 Protein involved with Nam7p and Upf3p in decay of mRNA containing nonsense codons YHR097C YHR097C YHR097C 0.3 19.5 0.8 Protein of unknown function YHR101C BIG1 BIG1 0.1 38 0.2 Protein required for normal growth on glucose, suppressor of rot1 rot2 synthetic lethality YHR123W EPT1 EPT1 0.8 13.5 2 sn-1,2-Diacylglycerol ethanolaminephosphotransferase YIL004C BET1 BET1 1.1 10 3.9 Synaptobrevin (v-SNARE) homolog present on ER vesicles recycling from Golgi YIL106W MOB1 MOB1 1.0 23 1.5 Protein required for completion of mitosis and maintenance of ploidy YIL111W COX5B COX5B 1.3 18 2.6 Cytochrome-c oxidase chain Vb, expressed under anaerobic conditions YIL177C YIL177C YIL177C 1.8 12.5 5 Protein with similarity to subtelomerically-encoded proteins including Yjl225p, Yfl068p, and Yhl093p YJL001W PRE3 PRE3 4.5 16 10.7 Proteasome subunit beta1_sc, involved in peptidyl-glutamyl peptide hydrolytic activity of the proteasome YJL024C APS3 APS3 0.3 15 0.7 Clathrin-associated protein (AP) complex, small subunit YJL041W NSP1 NSP1 1.1 15 2.9 Nuclear pore protein (nucleoporin) with XFXFG motifs YJL206C-A YJL206C-A YJL206CA 2.2 13 6.2 YJL225C YJL225C YJL225C 4.2 14 11.4 Protein with similarity to other subtelomerically-encoded proteins including Yil177p, Yhr219p, and Yhl079p YJR021C MER2 MER2 0.3 34 0.3 Meiotic recombination protein YJR079W YJR079W YJR079W 0.3 11 1.2 Protein of unknown function YKL006C-A SFT1 SFT1 0.6 13 1.7 V-SNARE-like protein required for vesicle traffic between Golgi compartments YKL081W TEF4 TEF4 4.5 10 15.8 Translation elongation factor EF-1gamma YKL190W CNB1 CNB1 5.3 17.5 11.5 Calcineurin regulatory (B) subunit YLL050C COF1 COF1 15.4 21 26.4 Cofilin, actin binding and severing protein YLR078C BOS1 BOS1 1.6 14 4.1 Synaptobrevin (v-SNARE) homolog involved in ER to Golgi transport YLR128W YLR128W YLR128W 0.3 17 0.7 Protein of unknown function YLR202C YLR202C YLR202C 0.7 16 1.5 Protein of unknown function YLR275W SMD2 SMD2 1.2 21 2.3 U1 snRNP protein of the Sm class YLR306W UBC12 UBC12 0.2 18 0.4 Rub1p-conjugating enzyme, with similarity to ubiquitin- and ubiquitin-like protein-conjugating enzymes YLR426W YLR426W YLR426W 1.0 11 3.3 Protein with similarity to Fox2p, E. coli 3-oxoacyl-[acyl-carrier protein] reductase and insect-type alcohol dehydrogenase/ribitol dehydrogenase family YLR464W YLR464W YLR464W 0.3 14 0.8 Protein with similarity to other subtelomerically-coded proteins YML025C YML025C YML025C 0.7 24 1 Mitochondrial ribosomalprotein of the large subunit, belongs to the L4 family of prokaryotic ribosomal proteins YML056C YML056C YML056C 7.7 11 25.7 Protein with similarity to inosine-5'-monophosphate dehydrogenase YML067C YML067C YML067C 2.7 12 8.7 Protein of unknown function YML085C TUB1 TUB1 2.6 15 6.1 Tubulin alpha-1 chain, required for mitosis and karyogamy YML094W PFD5 PFD5 1.8 15 4.4 YML124C TUB3 TUB3 3.5 21 6.2 Tubulin alpha-3 chain, non-essential YMR033W ARP9 ARP9 1.2 16 2.9 Protein with similarity to actin and actin-related proteins Arp1p-Arp10p YMR079W SEC14 SEC14 2.7 14 7.3 Phosphatidylinositol/phosphatidylcholine (PI/PC)-transfer protein, required for transport of secretory proteins from Golgi complex YMR116C BEL1 BEL1 43.9 13 124 Abundant protein with effects on translational efficiency and cell size, has two WD (WD-40) repeats YMR125W GCR3 GCR3 1.1 12 3.2 Gcr3 YMR133W REC114 REC114 #N/A 41 #N/A Meiotic recombination protein, mutants are defective in double-strand break formation YMR201C RAD14 RAD14 0.4 #N/A-nc #N/A Zinc-binding protein of nucleotide excision repairosome and homolog of human XPA xeroderma pigmentosum gene product YMR225C MRPL44 MRPL44 1.0 14 2.6 Mitochondrial ribosomal protein of the large subunit; (YmR44) YMR292W YMR292W YMR292W 5.3 9 22.2 Protein of unknown function YNL050C YNL050C YNL050C 1.2 12 3.6 Protein of unknown function YNL112W DBP2 DBP2 11.5 7 61.5 ATP-dependent RNA helicase of DEAD box family YNL130C CPT1 CPT1 2.1 21 3.7 sn-1,2-Diacylglycerol cholinephosphotransferase, catalyzes displacement of CMP from a CDP-alcohol YNL147W YNL147W YNL147W 2.8 12 8.6 YNL246W YNL246W YNL246W 0.9 16 2.1 Protein with similarity to Drosophila melanogaster SET protein YNL265C YNL265C YNL265C 0.6 20 1.1 Protein with similarity to Nuf1p YNL312W RFA2 RFA2 3.0 19 5.9 DNA replication factor A, 36K subunit; phosphorylated at the G1/S transition and dephosphorylated at mitosis YNL339C YNL339C YNL339C 6.4 15 16.2 Protein of unknown function YNR053C YNR053C YNR053C 5.2 11 17.9 Protein with similarity to human breast tumor-associated autoantigen YOL047C YOL047C YOL047C #N/A 17 #N/A Protein of unknown function YOR074C CDC21 CDC21 0.4 12.5 1.4 Thymidylate synthase, converts dUMP to dTMP YOR122C PFY1 PFY1 12.0 24 18.8 Profilin, can act to prevent actin polymerization and to complex with monomeric actin YOR221C YOR221C YOR221C 0.7 28 0.9 Malonyl CoA YOR318C YOR318C YOR318C 0.1 28 0.2 Protein of unknown function YPL031C PHO85 PHO85 1.2 22 2.1 Cyclin-dependent protein kinase that interacts with cyclin Pho80p to regulate phosphate pathway, also interacts with other Pho80p-like cyclins YPL075W GCR1 GCR1 0.7 25 1 Protein required for expression of glycolytic genes; causes same spectrum of enzymatic changes as does Gcr2p, activator of glycolytic genes YPL129W ANC1 ANC1 2.2 11 7.4 RNA polymerase transcription initiation factor TFIIF (factor g), small subunit, component of RNA polymerase holoenzyme, Kornberg's mediator (SRB) subcomplex, and the SWI/SNF complex YPL175W SPT14 SPT14 0.2 23 0.4 N-acetylglucosaminyltransferase, required for GPI anchor synthesis YPL218W SAR1 SAR1 5.8 14 15.1 GTP-binding protein of the arf family (ras superfamily) and component of COPII coat of vesicles involved in endoplasmic reticulum to Golgi transport YPL241C CIN2 CIN2 0.2 10 0.8 Protein involved in chromosome segregation MISSING YPL249C-A YPL283C YPL283C YPL283C 5.8 14 15.2 Protein with similarity to other subtelomerically-encoded protein YPR028W YPR028W YPR028W 10.6 22 18 YPR063C YPR063C YPR063C 2.5 12 7.2 Protein of unknown function YPR111W DBF20 DBF20 0.2 21 0.3 Cell cycle protein kinase related to Dbf2p, involved in termination of M-phase YPR187W RPB6 RPB6 5.9 13 17.4 Shared subunit of RNA polymerases I, II, and III (ABC23) YPR202W YPR202W YPR202W 0.4 #N/A-nc #N/A Protein with similarity to other subtelomerically-encoded proteins